gnb1
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  • Official Full Name
  • Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide 1
  • Background
  • Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene.
  • Synonyms
  • Gβ-1-Subunit; GNB1; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide binding protein (G protein), beta polypeptide 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1; Beta subunit signal transducing proteins GS/GI; G protein beta 1 subunit; GBB1; Guanine nucleotide binding protein beta 1 subunit; Transducin beta chain 1; OTTHUMP00000001107; G protein, beta-1 subunit
Cat.#:GNB1-5051HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNB1 Protein, GST-tagged
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Cat.#:GNB1-13353HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNB1, GST-tagged
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Cat.#:GNB1-172HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNB1, His-tagged
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Cat.#:GNB1-30631THTag:Flag|His
Source (Host):Species:Human
Product nameRecombinant Human Human Human GNAI1
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Cat.#:GNB1-31359THTag:Flag|His
Source (Host):Species:Human
Product nameRecombinant Human Human Human Human ADRB2
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Cat.#:GNB1-7025MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GNB1 Protein
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Cat.#:GNB1-2600RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GNB1 Protein
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Cat.#:GNB1-1896RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GNB1 Protein, His-tagged
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Cat.#:GNB1-2059CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GNB1
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Cat.#:GNB1-5864HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human GNB1 293 Cell Lysate
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Involved Pathway

GNB1 involved in several pathways and played different roles in them. We selected most pathways GNB1 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
ARF6; FIGF; ELK1; MAPK1; PDGFD; GNG5; RAF1; PLA2G4F; STK4; PTPN11
Chemokine signaling pathway
ARRB2; CCL11; CCL23; CXCR1; GM13304; PIK3R3; CCL28; CXCR5; Ccl21c; SHC2
PIK-Akt signaling pathway
ITGA8; IL6; ITGA7; LPAR4; PIK3R1; FLT1; TSC1; IFNA4; FGF1; IL3RA
Circadian entrainment
CACNA1H; GNG8; PRKACB; KCNJ9; CACNA1G; GRIA1; CAMK2G; KCNJ3; GUCY1A3; CALM1
Retrograde endocannabinoid signaling
GNG2; SLC17A6; GNGT1; GNAI3; GNG3; GNB4; GABRD; NAPEPLD; GRIA2; GRIA4
Glutamatergic synapse
SHANK2; PLCB3; GNG13; PLA2G4D; PPP3R2; GRIN2B; GRIN2D; GRIK3; PRKACB; HOMER2
Cholinergic synapse
PRKACG; AKT1; GNA11; CREB5; AKR1C1; PIK3R1; PLCB2; AKT2; KCNJ2; BCL2
Serotonergic synapse
GNG11; HTR4; GABRB2; MAPK3; APP; HTR2A; GNAS; HTR5A; PLCB3; GNAQ
GABAergic synapse
PRKCB; GABARAPL2; GAD2; SRC; GNG10; GPHN; NSF; GNG13; GABRQ; GABARAP
Dopaminergic synapse
PLCB2; CREB3L4; KIF5B; DDC; PPP2R2B; ARNTL; GNAI3; ITPR3; SLC18A2; GNAS
Olfactory transduction
SLC8A1; CALML5; OR3A2; PRKACG; OLFR502; OLFR481; OR2B3; OLFR469; CALM2; CNGA3
Taste transduction
ALPHA-ENAC; TAS2R116; PRKACB; PRKACA; Adcy4; TAS2R121; GRM4; TAS2R7; PRKACG; TAS2R117
Phototransduction
GUCY2F; RHO; CALML5; GNB4B; GRK7B; GNB1A; GNAT2; CALM3B; GUCA1B; CNGA1
Morphine addiction
PDE8B; GABRA6; GABRR3; PRKACA; ARRB1; GNG10; PRKCG; GNG5; PDE7A; GRK6
Alcoholism
HIST1H2BC; HIST1H4M; PKIA; HIST1H3H; HDAC8; CREB3L1; HIST1H2BG; HDAC1; HIST2H3A; HIST1H2AH
Pathways in cancer
FGF11; PRKCG; ARAF; RALBP1; GSTP1; BAD; FIGF; MET; CBLC; XIAP

Protein Function

GNB1 has several biochemical functions, for example, GTPase activity, GTPase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNB1 itself. We selected most functions GNB1 had, and list some proteins which have the same functions with GNB1. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activity
Related Protein RAB6A; RAB3DB; RAB39BB; RAB7; RAB32A; RAB5AB; RRAGCA; GNA11; GNAV1; RAB18A
Function GTPase binding
Related Protein PTPRN; MARCH5; RASA1; HSP90AA1; STOML2; GNB2; VPS41; YBX1; GOLGA4; LCP1
Function protein binding
Related Protein MAGEA2; FIGNL1; TSC2; CNTNAP1; COMMD10; PPP2R3A; COL4A3; RBMS1; MIS12; HOOK2
Function protein complex binding
Related Protein PEX26; KIF11; SHANK1; NOG; ABP1; CRHR1; EP300; WASF2; PFKP; CDK4
Function signal transducer activity
Related Protein TAS2R201.1; TAAR9; DRD7; VMN1R50; ZP3; V2RH7; OLFR13; OLFR186; SP110; AGTR1B
Function spectrin binding
Related Protein EPB49; PTPRN; STX4A; GBP1; DYNC1I1; DCTN2; UNC13A; PDE6G; SLC26A5; SPTAN1
Function type 1 angiotensin receptor binding
Related Protein TYK2; GNA13B; GNG3; JAK2; AGT; ARAP1; ARRB2; BDKRB2; GNA13A; GNA13

Interacting Protein

GNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNB1.
GNGT1; a8k1f4_human; GNAI2; Cdk1; NCF2; MCC; STIP1; MLF1; Cep76; PSMD2; q53fc7_human; Trim69; Haus1; NUDCD3; q96be0_human; PFDN5; MAP3K3; AARSD1; Mau2