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Official Full Name grainyhead-like 3 (Drosophila)
Background This gene encodes a member of the grainyhead family of transcription factors. The encoded protein may function as a transcription factor during development, and has been shown to stimulate migration of endothelial cells. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms GRHL3; grainyhead-like 3 (Drosophila); TFCP2L4, transcription factor CP2 like 4; grainyhead-like protein 3 homolog; SOM; Drosophila; Grainyhead like 3; Grainyhead like protein 3 homolog; Sister of mammalian grainyhead protein; TFCP2L4; Transcription factor CP2 like 4; OTTHUMP00000003072; OTTHUMP00000003297; OTTHUMP00000003298; OTTHUMP00000234795; transcription factor hSOM1; sister of mammalian grainyhead; sister-of-mammalian grainyhead; transcription factor CP2-like 4
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GRHL3-13525H Recombinant Human GRHL3, His-tagged E.coli His
    Human GRHL3-2367H Recombinant Human GRHL3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human GRHL3-5327H Recombinant Human GRHL3 Protein, GST-tagged Wheat Germ GST
    Mouse GRHL3-7255M Recombinant Mouse GRHL3 Protein Mammalian Cell His

    GRHL3 involved in several pathways and played different roles in them. We selected most pathways GRHL3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRHL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    GRHL3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GRHL3 itself. We selected most functions GRHL3 had, and list some proteins which have the same functions with GRHL3. You can find most of the proteins on our site.

    Function Related Protein
    chromatin DNA binding AASS; H2AFZ; RXRA; THRA; H1F0; FOXO3; XBP1; INSM1B; VAX1; BCL6
    protein binding GATA6; IL5RA; CDK15; EDEM1; IL1R2; LETMD1; AGO1; KCNA2; PARVG; AP1S2
    sequence-specific DNA binding RARAB; NR2F2; SATB1A; ZGPAT; NKX2.3; SOX2; RORA; NKX2.4B; ZNF397; HSFY1
    transcription factor activity, sequence-specific DNA binding GLI2; FOXA2; ZKSCAN4; MEF2D; ZIC1; TSC22D3; POU5F1; ZFP42; ZBTB11; POU5F3
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding RAD21; NKX2-5; RXRB; PLAGL1; BARHL1A; ELF5; NEUROD2; GATA1A; MAFG; MYF5

    GRHL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRHL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRHL3.


    Pourhoseini, S; Seth, RK; et al. Upregulation of miR21 and Repression of Grhl3 by Leptin Mediates Sinusoidal Endothelial Injury in Experimental Nonalcoholic Steatohepatitis. PLOS ONE 10:-(2015).
    Gordon, WM; Zeller, MD; et al. A GRHL3-regulated repair pathway suppresses immune-mediated epidermal hyperplasia. JOURNAL OF CLINICAL INVESTIGATION 124:5205-5218(2014).

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