GRIN2D

  • Official Full Name

    glutamate receptor, ionotropic, N-methyl D-aspartate 2D

  • Overview

    N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]

  • Synonyms

    GRIN2D;glutamate receptor, ionotropic, N-methyl D-aspartate 2D;EB11;NR2D;GluN2D;NMDAR2D;glutamate receptor ionotropic, NMDA 2D;estrogen receptor binding CpG island;N-methyl D-aspartate receptor subtype 2D;N-methyl-d-aspartate receptor subunit 2D;glutamate [NMDA] receptor subunit epsilon-4

Recombinant Proteins

  • Rat
  • Human
  • Mouse
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GRIN2D-2703R Recombinant Rat GRIN2D Protein Mammalian Cells Rat His
GRIN2D-611H Recombinant Human GRIN2D Mammalian Cells Human His
GRIN2D-7273M Recombinant Mouse GRIN2D Protein Mammalian Cells Mouse His
GRIN2D-2216H Recombinant Human GRIN2D Protein, His-tagged E.coli Human His Phe28-Ala584
GRIN2D-2357R Recombinant Rat GRIN2D Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GRIN2D-2357R-B Recombinant Rat GRIN2D Protein Pre-coupled Magnetic Beads HEK293 Rat
GRIN2D-3078H Recombinant Human GRIN2D Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
GRIN2D-3078H-B Recombinant Human GRIN2D Protein Pre-coupled Magnetic Beads HEK293 Human
GRIN2D-3932M Recombinant Mouse GRIN2D Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
GRIN2D-3932M-B Recombinant Mouse GRIN2D Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    GRIN2D involved in several pathways and played different roles in them. We selected most pathways GRIN2D participated on our site, such as Calcium signaling pathway,cAMP signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Circadian entrainment MAPK1,GNB3,GNG3,CAMK2B,GNAI3,GNG4,KCNJ3,FOS,GNAI1,NOS1
    Alcoholism GNB4,HIST3H2BB,TH,H3F3A,HDAC4,HIST1H4E,GNG10,GM14476,SLC18A2,HIST1H3G
    Calcium signaling pathway CALM2,RYR1B,P2RX4,TACR3A,MYLK4,CACNA1SA,CHRM5A,HTR4,PRKCB,ADRB3B
    Alzheimers disease NDUFA6,COX4I1,COX7B,PSEN1,IL1B2,ATP2A2,PPP3CB,CDK5R1,SDHA,COX6C
    Long-term potentiation PPP1CC,GNAQ,GRIA2,PLCB1,MAPK1,PRKACG,RPS6KA3,PPP1CA,MAPK3,GRIA1
    Nicotine addiction SLC17A7,GRIN3B,SLC17A6,GABRA5,GRIN1,GABRB1,GABRB2,GABRA3,GRIN3A,CHRNA6
    cAMP signaling pathway PPP1R12A,GPR81,ATP2A2,PLN,CAMK2D,VAV2,GABBR1,PRKACB,SOX9,CAMK2A
    Amyotrophic lateral sclerosis (ALS) MAPK12,GPX1,Casp3,CASP1,GRIA2,SOD1,CAT,PPP3CC,TNF,MAP3K5
    Cocaine addiction FOSB,SLC18A1,MAOA,GRIN2B,GNAI3,RELA,GRM2,PRKACB,CDK5,GPSM1

    Protein Function

    GRIN2D has several biochemical functions, for example, NMDA glutamate receptor activity,extracellular-glutamate-gated ion channel activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN2D itself. We selected most functions GRIN2D had, and list some proteins which have the same functions with GRIN2D. You can find most of the proteins on our site.

    Function Related Protein
    extracellular-glutamate-gated ion channel activity GRIA2,GRIA1A,GRIA4B,KBP,GRIK2,GRIN1B,GRIN1,GRIA3A,GRIA3,GRIN1A
    protein binding MYOZ2,RDM1,PIAS4,LRRK2,AUP1,UNC13B,VGLL4,APBB1,ZNF567,CTBP1
    NMDA glutamate receptor activity GRIN1A,GRIN2C,GRIN2BB,GRIN1B,GRIN3A,GRIN2A,GRIN3B,GRIN2B

    Interacting Protein

    GRIN2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN2D here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN2D.

    Dlg4;DLG4;Dlg3;CRK

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