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GRIN2D

  • Official Full Name

    glutamate receptor, ionotropic, N-methyl D-aspartate 2D

  • Overview

    N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]
  • Synonyms

    GRIN2D; glutamate receptor, ionotropic, N-methyl D-aspartate 2D; EB11; NR2D; GluN2D; NMDAR2D; glutamate receptor ionotropic, NMDA 2D; estrogen receptor binding CpG island; N-methyl D-aspartate receptor subtype 2D; N-methyl-d-aspartate receptor subunit 2D; glutamate [NMDA] receptor subunit epsilon-4;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GRIN2D-611H Recombinant Human GRIN2D Mammalian Cell His
Human GRIN2D-2216H Recombinant Human GRIN2D Protein, His-tagged E.coli N-His Phe28-Ala584
Human GRIN2D-3078H Recombinant Human GRIN2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GRIN2D-3078H-B Recombinant Human GRIN2D Protein Pre-coupled Magnetic Beads HEK293
Mouse GRIN2D-7273M Recombinant Mouse GRIN2D Protein Mammalian Cell His
Mouse GRIN2D-3932M Recombinant Mouse GRIN2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GRIN2D-3932M-B Recombinant Mouse GRIN2D Protein Pre-coupled Magnetic Beads HEK293
Rat GRIN2D-2703R Recombinant Rat GRIN2D Protein Mammalian Cell His
Rat GRIN2D-2357R Recombinant Rat GRIN2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GRIN2D-2357R-B Recombinant Rat GRIN2D Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GRIN2D involved in several pathways and played different roles in them. We selected most pathways GRIN2D participated on our site, such as Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayPLCD1;MYLK3;PLCD3;PLCE1;VDAC3;PPIFB;HRH1;HRH2;PPIF
cAMP signaling pathwayPLD2;RRAS2;HCN2;ATP1B4;CAMK4;PIK3CB;CALM4;ROCK2;FXYD1
Neuroactive ligand-receptor interactionGABRG3;CHRNB3B;GRM4;IL12;TAAR8A;CHRNA10;NR3C1;GRM6B;MC5RA
Circadian entrainmentGNAI2;CAMK2G;PLCB3;GRIA4;AKR1C1;GNB1;RYR3;KCNJ9;GRIN2A
Long-term potentiationRPS6KA2;GRIA1;PPP1CC;PPP3CC;BRAF;ARAF;GRIN2A;RPS6KA3;NRAS
Glutamatergic synapsePRKCG;GNG10;PLCB4;GRIK2;PLA2G4C;ADRBK2;PLA2G4D;GRIN2A;GRM3
Alzheimers diseaseNDUFA13;NDUFS2;TNF;CALM3;NCSTN;COX4I2;NDUFS5;UQCRB;LRP1
Amyotrophic lateral sclerosis (ALS)NEFM;SLC1A2;MAPK12;CAT;PPP3CA;BCL2;TOMM40;NEFH;NOS1
Cocaine addictionDRD2;GRIN3A;CDK5R1;BDNF;RGS9;TH;RELA;CREB3L4;CREB5
Nicotine addictionGABRQ;GABRA1;GRIA2;SLC17A6;GABRA6;GABRA3;GRIA3;GABRR2;GRIN2A
AlcoholismHDAC10;TH;HIST1H2BO;GNB1;KRAS;ATF4;DRD2;HIST1H2BL;MAOA

GRIN2D has several biochemical functions, for example, NMDA glutamate receptor activity, extracellular-glutamate-gated ion channel activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN2D itself. We selected most functions GRIN2D had, and list some proteins which have the same functions with GRIN2D. You can find most of the proteins on our site.

Function Related Protein
NMDA glutamate receptor activityGRIN2BB;GRIN2A;GRIN2B;GRIN3A;GRIN2C;GRIN2D;GRIN1B;GRIN1A;GRIN3B
extracellular-glutamate-gated ion channel activityGRIN3B;GRIN1;GRIA3B;GRIA1A;GRIK1;GRID2;GRIN3A;GRID1;GRIA3
protein bindingCSPP1;EGLN3;OAS3;PSMB1;RPL30;SEC16B;KCTD5;FNDC3B;MELK

GRIN2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN2D here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN2D.

Dlg4; DLG4; Dlg3; CRK

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