GRIN2D Protein, glutamate receptor, ionotropic, N-methyl D-aspartate 2D


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Official Full Name glutamate receptor, ionotropic, N-methyl D-aspartate 2D
Background N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]
Synonyms GRIN2D; glutamate receptor, ionotropic, N-methyl D-aspartate 2D; EB11; NR2D; GluN2D; NMDAR2D; glutamate receptor ionotropic, NMDA 2D; estrogen receptor binding CpG island; N-methyl D-aspartate receptor subtype 2D; N-methyl-d-aspartate receptor subunit 2D; glutamate [NMDA] receptor subunit epsilon-4;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GRIN2D-611H Recombinant Human GRIN2D Mammalian Cell His
    Mouse GRIN2D-7273M Recombinant Mouse GRIN2D Protein Mammalian Cell His
    Rat GRIN2D-2703R Recombinant Rat GRIN2D Protein Mammalian Cell His

    GRIN2D involved in several pathways and played different roles in them. We selected most pathways GRIN2D participated on our site, such as Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling pathway CAMK2D2; CACNA1D; ADRA1D; SLC8A3; ITPKA; PHKA1; ERBB4; PPP3CC; ORAI2; P2RX7
    cAMP signaling pathway ATP2B4; CALML5; AKT2; GRIN1; SLC9A1; LOC100328615; GIPR; Adcy4; GRIN3B; CREB3L2
    Neuroactive ligand-receptor interaction GALR3; NPY5R; EDNRBA; P2RX8; THRA; GRM4; CCKAR; GRIA2; TAAR14I; TAAR14J
    Circadian entrainment GNG5; CALM1; MTNR1A; NOS1; GNB4; NOS1AP; GNAO1; PER3; MTNR1B; CAMK2B
    Long-term potentiation PPP3CA; PPP3CC; PPP3R2; CAMK2G; CALML3; PPP1CA; CAMK2D; GRIN2D; HRAS; CAMK2B
    Glutamatergic synapse GLS; GRIA4; GRIN1; TRPC1; GLUL; GRIA3; GRIN3A; PRKCB; PLCB2; HOMER3
    Alzheimers disease UQCRQ; NDUFS3; CHP; ATP5J; FAS; NDUFB7; NDUFA4L2; NDUFA1; mt-Atp8; ATP5G3
    Amyotrophic lateral sclerosis (ALS) MAPK13; PPP3R1; CASP1; NEFL; MAPK11; GRIN2D; GRIN2C; BAX; TNF; PPP3CB
    Cocaine addiction PRKACA; CREB3L4; DRD1; PDYN; GRM2; GNAI1; FOSB; GRIN3A; GRIA2; SLC18A1
    Amphetamine addiction ARC; JUN; CAMK2G; PPP1CB; GRIA3; CREB3; CREB3L1; CALM1; PDYN; PRKACG
    Nicotine addiction GRIN2C; GRIN3B; GABRR3; SLC17A7; GABRG1; GABRE; GABRA5; GRIN2A; GABRB3; GABRG2
    Alcoholism HIST1H2AA; SLC18A2; HIST1H4M; H3F3A; HDAC5; HIST1H3D; ADORA2A; BDNF; SHC4; GRB2

    GRIN2D has several biochemical functions, for example, NMDA glutamate receptor activity, extracellular-glutamate-gated ion channel activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN2D itself. We selected most functions GRIN2D had, and list some proteins which have the same functions with GRIN2D. You can find most of the proteins on our site.

    Function Related Protein
    NMDA glutamate receptor activity GRIN3B; GRIN2C; GRIN1B; GRIN2BB; GRIN1A; GRIN2D; GRIN2A; GRIN2B; GRIN3A
    extracellular-glutamate-gated ion channel activity GRIA3A; GRIN3A; GRIN2D; GRID1; GRIN3B; GRIN1B; GRIK5; GRID2; GRIN2A; GRIK4
    protein binding MAT2B; FAM104A; MCC; DTX1; ACTB; CLU; TXNRD3; ELANE; CCDC170; EPM2AIP1

    GRIN2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN2D here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN2D.

    Dlg4; DLG4; Dlg3; CRK

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