|Official Full Name||glutamate receptor, ionotropic, N-methyl D-aspartate 2D|
|Background||N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]|
|Synonyms||GRIN2D; glutamate receptor, ionotropic, N-methyl D-aspartate 2D; EB11; NR2D; GluN2D; NMDAR2D; glutamate receptor ionotropic, NMDA 2D; estrogen receptor binding CpG island; N-methyl D-aspartate receptor subtype 2D; N-methyl-d-aspartate receptor subunit 2D; glutamate [NMDA] receptor subunit epsilon-4;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GRIN2D involved in several pathways and played different roles in them. We selected most pathways GRIN2D participated on our site, such as Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Calcium signaling pathway||CAMK2D2; CACNA1D; ADRA1D; SLC8A3; ITPKA; PHKA1; ERBB4; PPP3CC; ORAI2; P2RX7|
|cAMP signaling pathway||ATP2B4; CALML5; AKT2; GRIN1; SLC9A1; LOC100328615; GIPR; Adcy4; GRIN3B; CREB3L2|
|Neuroactive ligand-receptor interaction||GALR3; NPY5R; EDNRBA; P2RX8; THRA; GRM4; CCKAR; GRIA2; TAAR14I; TAAR14J|
|Circadian entrainment||GNG5; CALM1; MTNR1A; NOS1; GNB4; NOS1AP; GNAO1; PER3; MTNR1B; CAMK2B|
|Long-term potentiation||PPP3CA; PPP3CC; PPP3R2; CAMK2G; CALML3; PPP1CA; CAMK2D; GRIN2D; HRAS; CAMK2B|
|Glutamatergic synapse||GLS; GRIA4; GRIN1; TRPC1; GLUL; GRIA3; GRIN3A; PRKCB; PLCB2; HOMER3|
|Alzheimers disease||UQCRQ; NDUFS3; CHP; ATP5J; FAS; NDUFB7; NDUFA4L2; NDUFA1; mt-Atp8; ATP5G3|
|Amyotrophic lateral sclerosis (ALS)||MAPK13; PPP3R1; CASP1; NEFL; MAPK11; GRIN2D; GRIN2C; BAX; TNF; PPP3CB|
|Cocaine addiction||PRKACA; CREB3L4; DRD1; PDYN; GRM2; GNAI1; FOSB; GRIN3A; GRIA2; SLC18A1|
|Amphetamine addiction||ARC; JUN; CAMK2G; PPP1CB; GRIA3; CREB3; CREB3L1; CALM1; PDYN; PRKACG|
|Nicotine addiction||GRIN2C; GRIN3B; GABRR3; SLC17A7; GABRG1; GABRE; GABRA5; GRIN2A; GABRB3; GABRG2|
|Alcoholism||HIST1H2AA; SLC18A2; HIST1H4M; H3F3A; HDAC5; HIST1H3D; ADORA2A; BDNF; SHC4; GRB2|
GRIN2D has several biochemical functions, for example, NMDA glutamate receptor activity, extracellular-glutamate-gated ion channel activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN2D itself. We selected most functions GRIN2D had, and list some proteins which have the same functions with GRIN2D. You can find most of the proteins on our site.
|NMDA glutamate receptor activity||GRIN3B; GRIN2C; GRIN1B; GRIN2BB; GRIN1A; GRIN2D; GRIN2A; GRIN2B; GRIN3A|
|extracellular-glutamate-gated ion channel activity||GRIA3A; GRIN3A; GRIN2D; GRID1; GRIN3B; GRIN1B; GRIK5; GRID2; GRIN2A; GRIK4|
|protein binding||MAT2B; FAM104A; MCC; DTX1; ACTB; CLU; TXNRD3; ELANE; CCDC170; EPM2AIP1|
GRIN2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN2D here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN2D.
Dlg4; DLG4; Dlg3; CRK