| Official Full Name | glutamate receptor, ionotropic, N-methyl-D-aspartate 3A |
| Background | This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of;glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous;system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout;mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by;modulating NMDA receptor activity. |
| Synonyms | GRIN3A; glutamate receptor, ionotropic, N-methyl-D-aspartate 3A; glutamate [NMDA] receptor subunit 3A; GluN3A; NMDAR3A; N-methyl-D-aspartate receptor subtype 3A; NR3A; NMDAR-L; FLJ45414 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
GRIN3A involved in several pathways and played different roles in them. We selected most pathways GRIN3A participated on our site, such as Alcoholism, Amphetamine addiction, Cocaine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alcoholism | HIST2H2BB; HDAC8; HIST1H2AN; HIST1H2BG; CREB3; GNG2; HIST1H4M; GRIN2C; HIST1H3I; SLC29A1 |
| Amphetamine addiction | CALM4; GRIA2; PPP3CC; CREB3L1; CALM1; GRIN2B; DDC; ARC; PPP3CA; CAMK2A |
| Cocaine addiction | GRIN3A; GNAS; DRD1; SLC18A2; NFKB1; CREB5; SLC6A3; GRIN2C; DLG4; PRKACB |
| Glutamatergic synapse | GRIN3B; SLC17A7; SLC38A3; GNAI3; PPP3R2; HOMER3; GRM7; GRIN2B; PLD2; GNG8 |
| Neuroactive ligand-receptor interaction | MTNR1A; ADRA2DB; CHRNB4; Gh; P2RX4; MC5RA; S1PR4; SSTR2; TAAR12C; PTGDR |
| Nicotine addiction | GABRG2; GRIN2A; GRIN2B; GRIA1; GABRA1; GABRA4; SLC17A6; SLC17A7; GABRA2; GRIA2 |
| cAMP signaling pathway | ACOX3; HCN2; NFKBIA; FFAR2; MAPK10; ATP1A3; VIPR2; NFKB1; TNNI3; RAC1 |
GRIN3A has several biochemical functions, for example, NMDA glutamate receptor activity, contributes_to NMDA glutamate receptor activity, calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN3A itself. We selected most functions GRIN3A had, and list some proteins which have the same functions with GRIN3A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NMDA glutamate receptor activity | GRIN2BB; GRIN3A; GRIN1B; GRIN2A; GRIN2B; GRIN2C; GRIN3B; GRIN1A; GRIN2D |
| contributes_to NMDA glutamate receptor activity | PTK2B; GRIN2A; GRIN1; GRIN3A |
| calcium channel activity | CACNA1DA; TRPM1; SLC24A4A; TRPN1; TRPC4A; RYR1B; PKD2L1; GRIN2A; CACNA1SA; PKD1 |
| extracellular-glutamate-gated ion channel activity | GRIA4A; GRIK5; GRIN1A; GRIA2A; GRIN2D; GRIN2A; GRIA1B; KBP; GRIK4; GRIA2B |
| glycine binding | GLRA2; GSS; SRR; GRIN1; ALAS2; GLRA4A; GNMT; SIX2A; GRIN3B; GLRA1 |
| identical protein binding | GUCY2E; ATG101; SMAD4; ST13; NDC80; SMAD6; ACY3; CALHM1; VPS4B; HOOK3 |
| protein binding | PHYH; PLOD3; AAGAB; PEA15; CD3E; GFI1B; EPB41L1; LIMS1; KLK5; HACE1 |
| protein phosphatase 2A binding | STRN; RPS6KB1; PTPN1; CTTNBP2NL; PPME1; STRN4; GRIN3A; IGBP1; TRP53; MASTL |
GRIN3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN3A here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN3A.
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