GUCY1B3

  • Official Full Name

    Guanylate cyclase 1, soluble, beta 3

  • Overview

    Guanylate cyclase soluble subunit beta-1 is an enzyme that in humans is encoded by the GUCY1B3 gene. Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.

  • Synonyms

    GUCB3;GC-SB3;GUC1B3;GUCSB3;GUCY1B1;GC-S-beta-1;GUCY1B3;GCS-beta-1;GCS-beta-3;guanylate cyclase 1, soluble, beta 3;guanylate cyclase soluble subunit beta-1;Guanylate cyclase soluble subunit beta-3;Soluble guanylate cyclase small subunit

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Zebrafish
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GUCY1B3-13619H Recombinant Human GUCY1B3, His-tagged E.coli Human His 282-619a.a.
GUCY1B3-2019R Recombinant Rhesus monkey GUCY1B3 Protein, His-tagged Mammalian Cells Rhesus macaque His
GUCY1B3-2755R Recombinant Rat GUCY1B3 Protein Mammalian Cells Rat His
GUCY1B3-4491H Recombinant Human GUCY1B3 Protein, GST-tagged Wheat Germ Human GST
GUCY1B3-8100Z Recombinant Zebrafish GUCY1B3 Mammalian Cells Zebrafish His
GUCY1B3-5676HCL Recombinant Human GUCY1B3 293 Cell Lysate HEK293 Human Non
GUCY1B3-1840R Recombinant Rhesus Macaque GUCY1B3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
GUCY1B3-1840R-B Recombinant Rhesus Macaque GUCY1B3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GUCY1B3-2409R Recombinant Rat GUCY1B3 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GUCY1B3-2409R-B Recombinant Rat GUCY1B3 Protein Pre-coupled Magnetic Beads HEK293 Rat
GUCY1B3-3347HF Recombinant Full Length Human GUCY1B3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 619 amino acids

    Involved Pathway

    GUCY1B3 involved in several pathways and played different roles in them. We selected most pathways GUCY1B3 participated on our site, such as Purine metabolism,cGMP-PKG signaling pathway,Vascular smooth muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCY1B3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway IRS2,GATA4,SRF,CALM2,INSR,NFATC2,PPP1CA,PLCB1,CALML3,MYLK3
    Salivary secretion PRKCG,RYR3,VAMP2,GNAQ,BEST2,ATP2B1,PRKACG,PRKG2,CALM4,CAMP
    Gap junction TUBAL3,DRD2L,HTR2A,DRD2A,ADCY1B,TUBA8,MAP2K2B,CSNK1DB,PRKACG,PLCB4
    Vascular smooth muscle contraction EDNRAA,MYL9A,ITPR3,ADCY1A,RAF1B,NPR1,GNA11B,MYH11,CYP4A10,KCNMB3
    Renin secretion PPP3CA,Ren1,CALML5,PLCB3,PRKACB,PLCB2,CLCA5,ORAI1,PPP3CC,PTGER4
    Oxytocin signaling pathway PPP3R1,PPP1R12C,RGS2,NPR2,PLCB4,NOS3,CACNB1,CAMKK1,CACNA2D4,CAMK1D
    Platelet activation PLA2G4A,GNAI3,PTGIR,FCER1G,ACTB,ITGB3,PLA2G4C,RHOA,FERMT3,PLCB3
    Circadian entrainment KCNJ3,CACNA1G,RPS6KA5,GRIA2,GNG7,GRIN2C,KCNJ5,PLCB2,PLCB1,GNG4
    Long-term depression MAP2K2,GNAQ,PLCB3,RAF1,PPP2CA,NRAS,ARAF,GRIA3,HRAS,IGF1R

    Protein Function

    GUCY1B3 has several biochemical functions, for example, GTP binding,NOT adenylate cyclase activity,guanylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GUCY1B3 itself. We selected most functions GUCY1B3 had, and list some proteins which have the same functions with GUCY1B3. You can find most of the proteins on our site.

    Function Related Protein
    NOT adenylate cyclase activity GUCY2F,GC3,NPR1A,NPR1,GUCY2C,GC2,NPR2,NPR3,GUCY1A3
    GTP binding MX2,RAP1B,RAB3DB,AK3,GIMAP7,ATL3,FPGT,GSPT2,RAB9A,PPP1CA
    guanylate cyclase activity GUCY1A3,NPR1A,GUCY2F,GC2,NPR1,GUCY2E,NPR2,GC3,GUCY2C
    metal ion binding AMHR2,AGFG1B,ZBTB8B,PRKCBB,S100A10B,ARIH1L,TRIT1,VPS29,DMRT3A,LMAN1
    heme binding DGCR8,CYCS,CYP2D9,CYGB1,CYP3C4,HBBE2,EPX,NR1D1,CYP4F14,CYP2AD2
    receptor activity ADIPOR1,VMN1R54,TNFRSF9,FAS,CRTAM,KIR2DL3,GRIA2B,F2RL1,GRIA2A,LILRA3
    protein binding TNS1,AKAP17A,PCGF1,RAB7L1,C7orf53,BUC,TCF7,ZNF124,GMCL1,IDE

    Interacting Protein

    GUCY1B3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCY1B3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCY1B3.

    GUCY1A3;LIN7A

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