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FGFR1

  • Official Full Name

    fibroblast growth factor receptor 1

  • Overview

    Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome.
  • Synonyms

    FLG; FGFR1; fibroblast growth factor receptor 1; CEK; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; FLJ99988; bFGF-R-1; OTTHUMP00000190874; OTTHUMP00000190875; OTTHUMP00000190876; OTTHUMP00000190877; OTTHUMP00000190879; OTTHUMP00000190880; OTTHUMP00000190881; OTTHUMP00000190885; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; H2; H3; H4; H5; Basic fibroblast growth factor receptor 1; N sam tyrosine kinase; Protein tyrosine kinase; Tyrosylprotein kinase; Hydroxyaryl protein kinase; Heparin binding growth factor receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Cynomolgus Monkey
  • Gallus gallus (Chicken)
  • Human
  • Monkey
  • Mouse
  • Rat
  • Rhesus
  • Rhesus Macaque
  • Xenopus laevis (African clawed frog)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human cells
  • Human Cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • SF9 insect cells
  • Wheat Germ
  • Yeast
  • C
  • hFc
  • His
  • DDK|His
  • Fc
  • Fc|His
  • His(C
  • ter)
  • Flag
  • GST
  • GST|His
  • his
  • His (Fc)
  • Avi
  • His|GST
  • His|S
  • His|T7
  • sumostar
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • Strep
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGFR1-605H Active Recombinant Human FGFR1, His-tagged, Biotinylated Human Cell His
Human FGFR1-697H Active Recombinant Human FGFR1 Protein, Fc Chimera Mammalian cells Fc
Human FGFR1-606H Active Recombinant Human FGFR1, Fc-tagged, Biotinylated Human Cell Fc
Human FGFR1-236H Active Recombinant Human FGFR1 Protein, His & GST-tagged Insect Cell His/GST
Human FGFR1-1405H Active Recombinant Human FGFR1, GST-tagged Sf9 Insect Cell GST 399-822 aa
Human FGFR1-236HAF555 Active Recombinant Human FGFR1 Protein, His/GST-tagged, Alexa Fluor 555 conjugated Insect Cell His/GST 658
Human FGFR1-236HAF488 Active Recombinant Human FGFR1 Protein, His/GST-tagged, Alexa Fluor 488 conjugated Insect Cell His/GST 658
Human FGFR1-1275H Acitve Recombinant Human FGFR1 protein(Met1-Lys310), hFc-tagged HEK293 C-hFc Met1-Lys310
Human FGFR1-236HAF647 Active Recombinant Human FGFR1 Protein, His/GST-tagged, Alexa Fluor 647 conjugated Insect Cell His/GST 658
Human FGFR1-236HF Active Recombinant Human FGFR1 Protein, His/GST-tagged, FITC conjugated Insect Cell His/GST 658
Human FGFR1-316H Recombinant Human Fibroblast Growth Factor Receptor 1, His-tagged HEK293 His
Human FGFR1-138H Recombinant Human FGFR1, Fc-His tagged Human Cell Fc/His
Human FGFR1-28890TH Recombinant Human FGFR1 N/A
Human FGFR1-8305H Recombinant Human FGFR1 Mammalian cells N/A
Human FGFR1-28886TH Recombinant Human FGFR1 N/A
Human FGFR1-312H Recombinant Human FGFR1, GST-tagged, Active Sf9 Insect Cell GST
Human FGFR1-207H Recombinant Human FGFR1 protein, His-tagged HEK293 His Ala1-Lys221
Human FGFR1-28834TH Recombinant Human FGFR1 N/A
Human FGFR1-485H Recombinant Human Fibroblast Growth Factor Receptor 1(IIIb) Mammalian cells N/A
Human FGFR1-18H Recombinant Human FGFR1 protein, His-tagged HEK293 His 355
Human FGFR1-111H Recombinant Human FGFR1 protein, T7/His-tagged E.coli T7/His
Human FGFR1-498H Recombinant Human FGFR1, Fc Chimera HEK293 Fc
Human FGFR1-208H Recombinant Human FGFR1 protein, DDK/His-tagged HEK293 DDK/His Arg22-Tyr374
Human FGFR1-486H Recombinant Human Fibroblast Growth Factor Receptor 1(IIIc) Mammalian cells N/A
Human FGFR1-210H Recombinant Human FGFR1 protein, DDK/His-tagged HEK293 DDK/His Arg22-Glu376
Human FGFR1-487H Recombinant Human Fibroblast Growth Factor Receptor 1 Beta Mammalian cells N/A
Human FGFR1-211H Recombinant Human FGFR1 protein, His-tagged Insect Cell His Met1 - Glu376
Human FGFR1-01H Recombinant Human Fibroblast Growth Factor Receptor 1, Fc-tagged Insect Cell Fc
Human FGFR1-45H Recombinant Human FGFR1 protein, Flag-tagged, Biotinylated Insect Cell Flag
Human FGFR1-4843H Recombinant Human Fibroblast Growth Factor Receptor 1, GST-tagged Sf9 Insect Cell GST
Human FGFR1-5417H Recombinant Human Fibroblast Growth Factor Receptor 1, His-tagged Insect Cell his
Human FGFR1-2765HCL Recombinant Human FGFR1 cell lysate Human Cell N/A
Human FGFR1-476HCL Recombinant Human FGFR1 cell lysate Insect Cell N/A
Human FGFR1-384H Recombinant Human FGFR1 protein, Strep-tagged HEK293 Strep 355
Human FGFR1-4121H Active Recombinant Human FGFR1 Protein, GST/His-tagged Insect Cell GST/His
Human FGFR1-362HB Recombinant Human FGFR1 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi It contains Arg22-Glu374.
Human FGFR1-5404H Recombinant Human FGFR1 protein, His-sumostar-tagged Yeast His-sumostar 22-376aa
Human FGFR1-5375H Recombinant Human FGFR1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FGFR1-1133H Active Recombinant Human FGFR1 Protein, His-tagged HEK293 His
Human FGFR1-28H Recombinant Active Human FGFR1 (W666R) Mutant Protein, GST-tagged Insect Cell GST
Human FGFR1-91H Recombinant Active Human FGFR1 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Arg22-Glu376
Human FGFR1-2915H Recombinant Human FGFR1 protein, His-tagged E.coli His 22-376aa
Human FGFR1-1414H Recombinant Human FGFR1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FGFR1-138HAF488 Recombinant Human FGFR1 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His 512
Human FGFR1-1134H Recombinant Human FGFR1 Protein (Trp471-Arg821), N-His tagged E.coli N-His Trp471-Arg821
Human FGFR1-138HAF647 Recombinant Human FGFR1 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His 512
Human FGFR1-2914H Recombinant Human FGFR1 protein, His-tagged E.coli His 156-376aa
Human FGFR1-138HF Recombinant Human FGFR1 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His 512
Human FGFR1-0260H Recombinant Human FGFR1 protein, His-tagged HEK293 His Met1-Lys310
Human FGFR1-4885HF Recombinant Full Length Human FGFR1 Protein, GST-tagged In Vitro Cell Free System GST 731 amino acids
Human FGFR1-4884HF Recombinant Full Length Human FGFR1 Protein In Vitro Cell Free System 1,025 amino acids
Human FGFR1-034H Recombinant Human FGFR1 Protein, His-tagged E.coli His
Human FGFR1-4122H Recombinant Human FGFR1 Protein Wheat Germ N/A
Human FGFR1-1056HFL Recombinant Full Length Human FGFR1 Protein, C-Flag-tagged Mammalian cells Flag
Human FGFR1-247H Recombinant Human FGFR1 Protein, Strep-tagged HEK293 Strep 822
Human FGFR1-142F Active Recombinant Human FGFR1 Protein (592 aa), Fc-tagged SF9 insect cells Fc 592
Human FGFR1-4123H Recombinant Human FGFR1 Protein, GST-tagged Wheat Germ GST
Human FGFR1-4407H Recombinant Human FGFR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FGFR1-4407H-B Recombinant Human FGFR1 Protein Pre-coupled Magnetic Beads HEK293
Human FGFR1-246H Recombinant Human FGFR1 Protein, His-tagged HEK293 His 822
Human FGFR1-2054H Recombinant Human FGFR1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human FGFR1-4112H Recombinant Human FGFR1 Protein (Met1-Glu285), C-His tagged Mammalian cells C-His Met1-Glu285
Human FGFR1-2856H Recombinant Human FGFR1 Protein (Met1-Pro285), C-His tagged Mammalian cells C-His Met1-Pro285
Human FGFR1-1348H Recombinant Human FGFR1 protein(Ala1-Lys221), hFc-tagged HEK293 C-hFc Ala1-Lys221
Human FGFR1-2056H Recombinant Human FGFR1 Protein, His-tagged Insect Cell His
Human FGFR1-138HAF555 Recombinant Human FGFR1 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His 512
Human FGFR1-715H Recombinant Human FGFR1 Protein, His-tagged Insect Cell His 22-374 aa
Human FGFR1-362H Recombinant Human FGFR1 protein, His-Avi-tagged HEK293 His-Avi Arg22-Glu374
Human FGFR1-1895H Recombinant Human FGFR1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FGFR1-153H Recombinant Human FGFR1 Protein, His-tagged Human cells His
Human FGFR1-152H Recombinant Human FGFR1 Protein, His-tagged Human Cells His
Human FGFR1-151H Recombinant Human FGFR1 Protein, His-tagged Human Cells His
Mouse Fgfr1-4015M Active Recombinant Mouse Fgfr1 protein(Met1-Glu376), hFc-tagged HEK293 C-hFc Met1-Glu376
Mouse Fgfr1-4016M Recombinant Mouse Fgfr1 protein, His-tagged HEK293 His Met1-Glu376
Mouse FGFR1-2133MCL Recombinant Mouse FGFR1 cell lysate Human Cell N/A
Mouse Fgfr1-4016MAF488 Recombinant Mouse Fgfr1 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 366
Mouse Fgfr1-4015MF Recombinant Mouse Fgfr1 Protein, Fc-tagged, FITC conjugated HEK293 Fc 596
Mouse Fgfr1-3000M Recombinant Mouse Fgfr1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Fgfr1-4015MAF488 Recombinant Mouse Fgfr1 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 596
Mouse Fgfr1-4015MAF555 Recombinant Mouse Fgfr1 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 596
Mouse Fgfr1-4016MAF555 Recombinant Mouse Fgfr1 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 366
Mouse Fgfr1-4015MAF647 Recombinant Mouse Fgfr1 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 596
Mouse Fgfr1-4016MAF647 Recombinant Mouse Fgfr1 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 366
Mouse Fgfr1-4016MF Recombinant Mouse Fgfr1 Protein, His-tagged, FITC conjugated HEK293 His 366
Rat Fgfr1-2339R Recombinant Rat Fgfr1 protein, His-tagged HEK293 His 22-376 aa
Rat FGFR1-2338R Recombinant Rat Fgfr1 protein, His/T7-tagged E.coli His/T7 Arg22~Glu376
Rat Fgfr1-1800R Recombinant Rat Fgfr1 protein, His & S-tagged E.coli His/S Met1~Glu89
Monkey FGFR1-66RAF488 Recombinant Monkey FGFR1 Protein, His-tagged, Alexa Fluor 488 conjugated His
Monkey FGFR1-66RAF555 Recombinant Monkey FGFR1 Protein, His-tagged, Alexa Fluor 555 conjugated His
Monkey FGFR1-8817RAF488 Recombinant Monkey FGFR1 Protein, Fc-tagged, Alexa Fluor 488 conjugated Fc
Monkey FGFR1-8817RAF555 Recombinant Monkey FGFR1 Protein, Fc-tagged, Alexa Fluor 555 conjugated Fc
Monkey FGFR1-66RF Recombinant Monkey FGFR1 Protein, His-tagged, FITC conjugated His
Monkey FGFR1-8817RF Recombinant Monkey FGFR1 Protein, Fc-tagged, FITC conjugated Fc
Monkey FGFR1-66RAF647 Recombinant Monkey FGFR1 Protein, His-tagged, Alexa Fluor 647 conjugated His
Monkey FGFR1-8817RAF647 Recombinant Monkey FGFR1 Protein, Fc-tagged, Alexa Fluor 647 conjugated Fc
Cynomolgus Monkey FGFR1-55C Recombinant Cynomolgus FGFR1, Fc tagged Mammalian Cell Fc
Cynomolgus Monkey FGFR1-67C Recombinant Cynomolgus FGFR1 protein, His-tagged HEK293 His
Cynomolgus Monkey FGFR1-1171CCL Recombinant Cynomolgus FGFR1 cell lysate Human Cell N/A
Cynomolgus Monkey FGFR1-5C-B Recombinant Cynomolgus Monkey FGFR1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey FGFR1-5C Recombinant Cynomolgus Monkey FGFR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Gallus gallus (Chicken) RFL14852GF Recombinant Full Length Chicken Fibroblast Growth Factor Receptor 1(Fgfr1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-819)
Rhesus FGFR1-8817C Active Recombinant Rhesus FGFR1 protein, hFc-tagged HEK293 hFc Met1-Tyr283
Rhesus Macaque FGFR1-1704R Recombinant Rhesus monkey FGFR1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FGFR1-66C Recombinant Rhesus FGFR1 protein, His-tagged HEK293 His Met1-Tyr283
Rhesus Macaque FGFR1-1526R Recombinant Rhesus Macaque FGFR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FGFR1-1526R-B Recombinant Rhesus Macaque FGFR1 Protein Pre-coupled Magnetic Beads HEK293
Xenopus laevis (African clawed frog) RFL5885XF Recombinant Full Length Xenopus Laevis Fibroblast Growth Factor Receptor 1(Fgfr1) Protein, His-Tagged E.coli expression system His Full Length (21-812)
Chicken FGFR1-7059C Recombinant Chicken FGFR1 Mammalian Cell His
Kit-1590 FGFR1 Functional Assay Kit N/A
Kit-1557 U2OS FGFR1 Bioassay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FGFR1 Related Articles
  • FGFR1 Related Gene Family
  • FGFR1 Related Research Area
  • FGFR1 Related Signal Pathway

FGFR1 involved in several pathways and played different roles in them. We selected most pathways FGFR1 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGFR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwaySTMN1B;ARR3B;PRKACBA;CACNG8;PPP3CA;GRB2;MAPK9;NTRK2B;FGF10
Ras signaling pathwayRASAL2;Pdgfa&Pdgfb;FGF11;ANGPT4;HRAS;MAPK3;PRKCB;PLA2G12A;KLK1B4
Rap signaling pathwayFgf15;MAPK12;ACTG1;LPAR2;MAP2K3;RAPGEF6;FGF12;Adcy4;FGF17
PIK-Akt signaling pathwayPPP2R1B;GNG5;FN1;NGF;RPS6KB1;MLST8;FGF8;LAMA4;TCL1B
Adherens junctionTCF7;CSNK2A1;FGFR1A;RHOAA;ACTN3B;TGFBR1B;SMAD4;WASL;FYNB
Signaling pathways regulating pluripotency of stem cellsESRRB;ID2;NODAL;TBX3;DLX5;ISL1;STAT3;SOX2;SMAD9
Regulation of actin cytoskeletonITGB8;ITGB7;EZR;FGF18A;FGF12A;GNG12;SLC9A1;NCKAP1L;PFN1
Pathways in cancerBIRC8;GNG11;RXRG;SPI1;NCOA4;RAD51;WNT2B;MSH6;BCL2
Proteoglycans in cancerMAP2K2;PIK3CB;ESR1;PIK3CD;ROCK2;SMAD2;ROCK1;ITGAV;PTPN11
Prostate cancerCASP9;RB1;AKT1;FOXA1;INSRR;PDGFA;CREB3L1;SPINK1;BAD
MelanomaFGF16;FGF8;IGF1R;HRAS;MITF;KRAS;FGF7;FGF19;FGFR1
Central carbon metabolism in cancerPDGFRA;SIRT6;MAPK3;MAP2K2;HIF1A;SLC16A3;PDHA2;PIK3CD;SCO2

FGFR1 has several biochemical functions, for example, ATP binding, cell adhesion molecule binding, fibroblast growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGFR1 itself. We selected most functions FGFR1 had, and list some proteins which have the same functions with FGFR1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingP2RX4A;PEO1;DSTYK;CHORDC1;LMTK2;ATP13A3;KCNJ10;DDX39AA;PANK2
cell adhesion molecule bindingITGB7;PVRL4;VCAM1;CXADR;NLGN4Y;SDCBP;PVRL3B;CD226;AMICA1
fibroblast growth factor bindingS100A13;FIBPA;SCN5A;CXCL13;FGFR3;FGFRL1;CEP57;FGFR2;RPS19
fibroblast growth factor-activated receptor activityFGFR4;FGFR1A;FGFR1;FGFR1B;FGFR3;FGFR2;FGFRL1
glycoprotein bindingCDH1;CSNK1D;F7;BMPR1B;FLNA;RAB14;LDLR;FYN;FBXO17
heparin bindingCECR1;FSTL1;VEGFAA;LPA;ADAMTS1;FGFBP3;CXCL11;MSTN;CYR61L1
identical protein bindingHAPLN2;BCL2;DRG1;VCP;G6PDX;DIAPH1;TPRGL;BNIP2;MID1
protein bindingTRPM8;THBS2;CARS;PIF1;CLDN1;TTC35;C19orf60;CDC20;RPN1
protein complex bindingPPFIA2;RAP1A;LCK;PDZK1;LCA5;PEX1;ULK1;ABI1;MTHFR
protein homodimerization activityKIAA0947;GIMAP7;VEGFA;APOA2;WWTR1;ACTN2;AMICA1;GZMA;TIRAP
protein tyrosine kinase activityHCK;KITA;ERBB4;FYNB;MAP3K9;DYRK1A;BCR;FGR;PDGFRB

FGFR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGFR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGFR1.

PLCG1; HTR1A; FGF2

Stachowiak, MK; Birkaya, B; et al. "Nuclear FGF Receptor-1 and CREB Binding Protein: An Integrative Signaling Module". JOURNAL OF CELLULAR PHYSIOLOGY 230:989-1002(2015).
Ambrosini, S; Sarchielli, E; et al. FIBROBLAST GROWTH FACTOR AND ENDOTHELIN-1 RECEPTORS MEDIATE THE RESPONSE OF HUMAN STRIATAL PRECURSOR CELLS TO HYPOXIA. NEUROSCIENCE 289:123-133(2015).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does DEFB103A interact with the human microbiome? 06/10/2022

DEFB103A plays a role in maintaining a balanced microbiome by exerting selective antimicrobial activity. Understanding this interaction is crucial for potential applications in microbiome-related disorders.

Can DEFB103A be used as a diagnostic marker for certain diseases? 05/01/2022

Research suggests that altered levels of DEFB103A expression may be associated with certain diseases. However, its specific use as a diagnostic marker requires further validation.

Are there any side effects or concerns associated with the therapeutic use of DEFB103A? 04/25/2022

While research is ongoing, potential side effects and concerns related to the therapeutic use of DEFB103A or its analogs need to be thoroughly investigated, including any possible immunogenicity.

How does DEFB103A contribute to the immune system? 02/08/2018

DEFB103A plays a crucial role in the innate immune system by acting as an antimicrobial peptide. It helps defend the body against a wide range of pathogens, including bacteria, viruses, and fungi.

What specific clinical conditions are associated with DEFB103A deficiency? 05/25/2017

DEFB103A deficiency has been linked to an increased susceptibility to various infections, particularly those affecting the skin and mucosal surfaces.

Customer Reviews (3)

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Reviews
05/01/2021

    FGFR1, a calcium-dependent phospholipid-binding protein, plays a crucial role in various cellular processes, making it a valuable tool for investigation.

    12/25/2018

      When combined with the support and quality assurance provided by the manufacturer, researchers can confidently utilize FGFR1 protein to unravel the intricate mechanisms underlying cellular processes, ultimately advancing scientific knowledge.

      07/24/2017

        The manufacturer can contribute to the research process by providing top-quality FGFR1 protein that meets rigorous standards of purity, stability, and reliability.

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