HCN2 Protein, hyperpolarization activated cyclic nucleotide-gated potassium channel 2


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Official Full Name hyperpolarization activated cyclic nucleotide-gated potassium channel 2
Background Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 is a protein that in humans is encoded by the HCN2 gene.
Synonyms HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
    • Species :
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse HCN2-7520M Recombinant Mouse HCN2 Protein Mammalian Cell His
    Rat HCN2-2807R Recombinant Rat HCN2 Protein Mammalian Cell His

    HCN2 involved in several pathways and played different roles in them. We selected most pathways HCN2 participated on our site, such as cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cAMP signaling pathway VAV3; GRIN2B; DRD1A; CAMK4; ATP2B1; PIK3R5; MAPK9; GLI1; HCN2; RAP1A

    HCN2 has several biochemical functions, for example, cAMP binding, identical protein binding, intracellular cAMP activated cation channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HCN2 itself. We selected most functions HCN2 had, and list some proteins which have the same functions with HCN2. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding PTPRG; SLC2A1; PPP1R13L; NIF3L1; GDF5; TRIM21; MPST; PON2; AGXT2; OAT
    intracellular cAMP activated cation channel activity HCN4; CNGA3; CNGA5; CNGA1; CNGA4; HCN2
    voltage-gated potassium channel activity KCNQ2; HCN4; KCNAB2B; KCNAB1; KCNMA1A; KCNF1A; KCNH6A; KCNA6A; KCNMA1; KCNC4
    voltage-gated sodium channel activity SCN1A; SCN9A; PKD2; HCN2; SCN4AA; SCN11A; SCN1LAB; SCN1BB; SCN8AB; SCN4A

    HCN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HCN2.

    Riesen, SC; Schober, KE; et al. Myocardial expression of hyperpolarization-activated, cyclic nucleotide-gated proteins in healthy cats and cats with hypertrophic cardiomyopathy. SCHWEIZER ARCHIV FUR TIERHEILKUNDE 155:143-147(2013).
    Yang, S; Xiong, CJ; et al. The distribution of HCN2-positive cells in the gastrointestinal tract of mice. JOURNAL OF ANATOMY 221:303-310(2012).

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