HDAC10
-
Official Full Name
histone deacetylase 10
-
Overview
The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
HDAC10; histone deacetylase 10; DKFZP761B039; HD10; MGC149722;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Insect Cells
- Mammalian Cell
- Mammalian cells
- Sf9 Insect Cell
- Wheat Germ
- C
- His
- FLAG
- GST
- GST|His
- His (Fc)
- Avi
- His|GST
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- HDAC10 Related Research Area
- HDAC10 Related Signal Pathway
HDAC10 involved in several pathways and played different roles in them. We selected most pathways HDAC10 participated on our site, such as Alcoholism, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HDAC10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Alcoholism | HDAC6;HIST1H4B;HIST1H4H;GM14478;DRD2;DRD1A;HIST1H4N;ATF6B;MAP2K1 |
Viral carcinogenesis | HIST1H2BM;GTF2H1;MAD1L1;CCND3;PRKACG;HLA-G;DNAJA3;HDAC2;RBL2 |
HDAC10 has several biochemical functions, for example, NAD-dependent histone deacetylase activity (H3-K14 specific), enzyme binding, histone deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HDAC10 itself. We selected most functions HDAC10 had, and list some proteins which have the same functions with HDAC10. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
NAD-dependent histone deacetylase activity (H3-K14 specific) | HDAC7;HDAC2;HDAC3;HDAC10;HDAC7A;HDAC1;HDAC8;HDAC5;HDAC4 |
enzyme binding | NCOA1;STC2;CSF3;APOA5;PTPLAD2;MLEC;KAT8;XRCC1;KDM4C |
histone deacetylase activity | SIRT1;HDAC9B;HDAC8;HDAC10;HDAC9;HDAC6;HDAC2;NACC2;SIRT2 |
histone deacetylase binding | CDC20;USF1;MECP2;HDAC5;FOXP3;PARK2;KLF4;WDTC1;XBP1 |
protein binding | SH3BP2;FCER2;DYDC1;RNF7;PDCL;EPRS;C3orf15;CDH5;WFDC9 |
protein deacetylase activity | HDAC1;HDAC2;HDAC3;HDAC9;SIRT1;SIRT2;SIN3A;HDAC4;HDAC10 |
HDAC10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HDAC10 here. Most of them are supplied by our site. Hope this information will be useful for your research of HDAC10.
HDAC3; HDAC2; NCOR2; P4HA1; RAC2; PDIA3; DNAJA1; FDFT1; COPB1; TXNDC5
- Q&As
- Reviews
Q&As (5)
Ask a questionHDAC10 may influence neuronal function by regulating the acetylation status of proteins involved in synaptic plasticity and neurodevelopment.
HDAC10 may affect the immune response by modulating the expression of genes involved in immune regulation, making it a potential target for immunotherapy.
HDAC10 inhibitors are being explored as potential anti-cancer agents, as they could help regulate gene expression and inhibit the growth of cancer cells.
Several clinical trials are investigating the efficacy and safety of HDAC10 inhibitors in different cancer types.
While its primary focus is often on cancer, HDAC10 has also been implicated in other diseases, including neurological disorders.
Customer Reviews (3)
Write a reviewit has demonstrated remarkable effectiveness in ELISA experiments, showcasing its reliability and accuracy in detecting and quantifying specific targets.
The reliable performance of the HDAC10 protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.
the HDAC10 protein has proven to be an invaluable asset in protein electron microscopy structure analysis.
Ask a Question for All HDAC10 Products
Required fields are marked with *
My Review for All HDAC10 Products
Required fields are marked with *