hdac10
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  • Official Full Name
  • histone deacetylase 10
  • Background
  • The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • HDAC10; histone deacetylase 10; DKFZP761B039; HD10; MGC149722
Cat.#:HDAC10-27261THTag:His-GST
Source (Host):Insect CellsSpecies:Human
Product nameRecombinant Human HDAC10 Protein, His-GST-tagged
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Cat.#:HDAC10-4640HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HDAC10 Protein, GST-tagged
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Cat.#:HDAC10-1588HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Histone Deacetylase 10, GST-tagged
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Cat.#:HDAC10-392HTag:GST/His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human HDAC10 protein, GST/His-tagged
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Cat.#:HDAC10-393HTag:FLAG
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human HDAC10 protein, FLAG-tagged
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Cat.#:HDAC10-401HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Histone Deacetylase 10, His-tagged
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Cat.#:HDAC10-7527MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HDAC10 Protein
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Cat.#:HDAC10-2815RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HDAC10 Protein
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Cat.#:HDAC10-10164ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HDAC10
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Cat.#:HDAC10-1354HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human HDAC10 (Active), GST-tagged
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Cat.#:HDAC10-5607HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HDAC10 293 Cell Lysate
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Involved Pathway

HDAC10 involved in several pathways and played different roles in them. We selected most pathways HDAC10 participated on our site, such as Alcoholism, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HDAC10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Alcoholism
HAT1; HIST1H2AI; GM6026; HIST3H2A; GNAS; ADORA2A; SHC4; GNGT2; HIST1H2AM; GNG12
Viral carcinogenesis
HDAC1; IL6ST; CASP8; SCRIB; CCNA2; ACTN1; UBE3A; KRAS; HIST1H4F; IRF3

Protein Function

HDAC10 has several biochemical functions, for example, NAD-dependent histone deacetylase activity (H3-K14 specific), enzyme binding, histone deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HDAC10 itself. We selected most functions HDAC10 had, and list some proteins which have the same functions with HDAC10. You can find most of the proteins on our site.
Function
Related Protein
Function NAD-dependent histone deacetylase activity (H3-K14 specific)
Related Protein HDAC8; HDAC3; HDAC10; HDAC1; HDAC11; HDAC9B; HDAC5; HDAC6; HDAC7; HDAC9
Function enzyme binding
Related Protein SELS; UGT1A7; HIST1H2AM; HDAC10; MARCH6; PRKCE; DDX5; SUDS3; TTN; FAM84B
Function histone deacetylase activity
Related Protein HDAC3; HDAC10; HDAC7; HDAC2; MTA2; HDAC6; HDAC5; HDAC4; NACC2; HDAC9
Function histone deacetylase binding
Related Protein RUNX2; NKX3; USF1; MEF2D; BCOR; NCOR1; NR2E1; GLI3; FOXP3; CEBPA
Function protein binding
Related Protein RBM3; ERCC4; TUBB2B; PFN1; VENTX; RELA; DPH3; FXYD6; SEC16B; Abcb1b
Function protein deacetylase activity
Related Protein SIN3A; SIRT1; HDAC5; SIRT2; HDAC3; HDAC1; HDAC4; HDAC2; HDAC10; HDAC9

Interacting Protein

HDAC10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HDAC10 here. Most of them are supplied by our site. Hope this information will be useful for your research of HDAC10.
HDAC3; HDAC2; NCOR2; P4HA1; RAC2; PDIA3; DNAJA1; FDFT1; COPB1; TXNDC5