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HDAC10

  • Official Full Name

    histone deacetylase 10

  • Overview

    The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    HDAC10; histone deacetylase 10; DKFZP761B039; HD10; MGC149722;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • C
  • His
  • FLAG
  • GST
  • GST|His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HDAC10-393H Active Recombinant Human HDAC10 protein, FLAG-tagged Insect Cell FLAG
Human HDAC10-1354H Active Recombinant Human HDAC10, GST-tagged Sf9 Insect Cell GST 1-482 aa
Human HDAC10-401H Active Recombinant Human Histone Deacetylase 10, His-tagged Insect Cell His
Human HDAC10-392H Active Recombinant Human HDAC10 protein, GST/His-tagged Insect Cell GST/His
Human HDAC10-1588H Recombinant Human Histone Deacetylase 10, GST-tagged Sf9 Insect Cell GST
Human HDAC10-4640H Recombinant Human HDAC10 Protein, GST-tagged Wheat Germ GST
Human HDAC10-27261TH Active Recombinant Human HDAC10 Protein, His-GST-tagged Insect Cells His/GST a.a. 1-481
Human HDAC10-5607HCL Recombinant Human HDAC10 293 Cell Lysate HEK293 N/A
Human HDAC10-2801H Recombinant Human HDAC10 Protein (Met1-Gln358), N-His tagged E.coli N-His Met1-Gln358
Human HDAC10-3610HF Recombinant Full Length Human HDAC10 Protein, GST-tagged In Vitro Cell Free System GST 669 amino acids
Human HDAC10-2800H Recombinant Human HDAC10 Protein (Met1-Ala669), C-His tagged Mammalian cells C-His Met1-Ala669
Mouse HDAC10-7527M Recombinant Mouse HDAC10 Protein Mammalian Cell His
Mouse HDAC10-4089M-B Recombinant Mouse HDAC10 Protein Pre-coupled Magnetic Beads HEK293
Mouse Hdac10-3367M Recombinant Mouse Hdac10 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse HDAC10-4089M Recombinant Mouse HDAC10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HDAC10-2815R Recombinant Rat HDAC10 Protein Mammalian Cell His
Rat Hdac10-1619R Recombinant Rat Hdac10 Protein, His-tagged E.coli N-His Met1-Glu302
Rat HDAC10-2470R Recombinant Rat HDAC10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HDAC10-2470R-B Recombinant Rat HDAC10 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HDAC10-10164Z Recombinant Zebrafish HDAC10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HDAC10 Related Research Area
  • HDAC10 Related Signal Pathway

HDAC10 involved in several pathways and played different roles in them. We selected most pathways HDAC10 participated on our site, such as Alcoholism, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HDAC10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AlcoholismHDAC6;HIST1H4B;HIST1H4H;GM14478;DRD2;DRD1A;HIST1H4N;ATF6B;MAP2K1
Viral carcinogenesisHIST1H2BM;GTF2H1;MAD1L1;CCND3;PRKACG;HLA-G;DNAJA3;HDAC2;RBL2

HDAC10 has several biochemical functions, for example, NAD-dependent histone deacetylase activity (H3-K14 specific), enzyme binding, histone deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HDAC10 itself. We selected most functions HDAC10 had, and list some proteins which have the same functions with HDAC10. You can find most of the proteins on our site.

Function Related Protein
NAD-dependent histone deacetylase activity (H3-K14 specific)HDAC7;HDAC2;HDAC3;HDAC10;HDAC7A;HDAC1;HDAC8;HDAC5;HDAC4
enzyme bindingNCOA1;STC2;CSF3;APOA5;PTPLAD2;MLEC;KAT8;XRCC1;KDM4C
histone deacetylase activitySIRT1;HDAC9B;HDAC8;HDAC10;HDAC9;HDAC6;HDAC2;NACC2;SIRT2
histone deacetylase bindingCDC20;USF1;MECP2;HDAC5;FOXP3;PARK2;KLF4;WDTC1;XBP1
protein bindingSH3BP2;FCER2;DYDC1;RNF7;PDCL;EPRS;C3orf15;CDH5;WFDC9
protein deacetylase activityHDAC1;HDAC2;HDAC3;HDAC9;SIRT1;SIRT2;SIN3A;HDAC4;HDAC10

HDAC10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HDAC10 here. Most of them are supplied by our site. Hope this information will be useful for your research of HDAC10.

HDAC3; HDAC2; NCOR2; P4HA1; RAC2; PDIA3; DNAJA1; FDFT1; COPB1; TXNDC5

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does HDAC10 impact neuronal function? 01/01/2023

HDAC10 may influence neuronal function by regulating the acetylation status of proteins involved in synaptic plasticity and neurodevelopment.

How does HDAC10 influence immune response in cancer? 09/03/2020

HDAC10 may affect the immune response by modulating the expression of genes involved in immune regulation, making it a potential target for immunotherapy.

What are the specific clinical applications of HDAC10 in cancer treatment? 02/22/2019

HDAC10 inhibitors are being explored as potential anti-cancer agents, as they could help regulate gene expression and inhibit the growth of cancer cells.

Are there any ongoing clinical trials targeting HDAC10 in cancer therapy? 10/22/2017

Several clinical trials are investigating the efficacy and safety of HDAC10 inhibitors in different cancer types.

Is HDAC10 exclusively associated with cancer, or does it have relevance in other diseases? 07/30/2016

While its primary focus is often on cancer, HDAC10 has also been implicated in other diseases, including neurological disorders.

Customer Reviews (3)

Write a review
Reviews
08/31/2020

    it has demonstrated remarkable effectiveness in ELISA experiments, showcasing its reliability and accuracy in detecting and quantifying specific targets.

    06/26/2019

      The reliable performance of the HDAC10 protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.

      09/12/2018

        the HDAC10 protein has proven to be an invaluable asset in protein electron microscopy structure analysis.

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