Recombinant Mouse Hdac10 Protein, Myc/DDK-tagged

• Cat.No.: Hdac10-3367M
• Product Overview: Purified recombinant protein of mouse full-length histone deacetylase 10 (Hdac10), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Polyamine deacetylase (PDAC), which acts preferentially on N8-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N1,N8-diacetylspermidine and very low activity, if any, toward N1-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells. May play a role in homologous recombination. May promote DNA mismatch repair.
• Molecular Mass: 72.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hdac10 histone deacetylase 10 [ Mus musculus (house mouse) ]
• Official Symbol: Hdac10
• Synonyms: HDAC10; histone deacetylase 10; Hd10; AW548891
• Gene ID: 170787
• mRNA Refseq: NM_199198
• Protein Refseq: NP_954668
• UniProt ID: Q6P3E7