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HIST1H1E

  • Official Full Name

    histone cluster 1, H1e

  • Overview

    Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]
  • Synonyms

    HIST1H1E; histone cluster 1, H1e; H1E; H1.4; H1F4; H1s-4; dJ221C16.5; histone H1.4; histone H1b; histone H1s-4; histone 1, H1e; H1 histone family, member 4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HIST1H1E-4775H Recombinant Human HIST1H1E Protein, GST-tagged Wheat Germ GST
Human HIST1H1E-5551HCL Recombinant Human HIST1H1E 293 Cell Lysate HEK293 N/A
Human HIST1H1E-3566HF Recombinant Full Length Human HIST1H1E Protein, GST-tagged In Vitro Cell Free System GST 219 amino acids
Mouse HIST1H1E-7646M Recombinant Mouse HIST1H1E Protein Mammalian Cell His
Mouse HIST1H1E-4177M Recombinant Mouse HIST1H1E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HIST1H1E-4177M-B Recombinant Mouse HIST1H1E Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HIST1H1E Related Research Area

HIST1H1E involved in several pathways and played different roles in them. We selected most pathways HIST1H1E participated on our site, such as Activation of DNA fragmentation factor, Apoptosis, Apoptosis induced DNA fragmentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H1E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of DNA fragmentation factorH1F0;HIST1H1B;DFFA;HMGB2;HIST1H1C;HIST1H1D;HIST1H1A;HIST1H1E;HMGB2A
ApoptosisXIAP;PIK3R1;VIML;PPP3CA;GZME;IRF4A;RNF8;PIK3R3B;DAPK3
Apoptosis induced DNA fragmentationHIST1H1B;H1F0;HIST1H1A;HMGB2;HIST1H1C;DFFA;HIST1H1D;HIST1H1E;HMGB2A
Apoptotic execution phaseCLSPN;SATB1;OCLN;STK24;DBNLB;PKP1;GAS2;CASP6L1;VIML
Cellular SenescenceCDKN2A;KDM6B;EP400;RBBP4;UBN1;MOV10;IGFBP7;HMGA1-RS1;POT1A
Cellular responses to stressCDKN2A;UVRAG;HIST1H1A;ST13;PRDX3;DYNLL2A;CDKN2B;CDK6;BAG3
DNA Damage/Telomere Stress Induced SenescenceHIST1H1B;HMGA1-RS1;UBN1;HIST1H1A;POT1;TERF2IP;POT1A;HMGA1B;EP400
Formation of Senescence-Associated Heterochromatin Foci (SAHF)HMGA1B;CABIN1;HIRA;ASF1A;HIST1H1E;UBN1;HIST1H1D;HIST1H1A;HMGA1-RS1

HIST1H1E has several biochemical functions, for example, chromatin DNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H1E itself. We selected most functions HIST1H1E had, and list some proteins which have the same functions with HIST1H1E. You can find most of the proteins on our site.

Function Related Protein
chromatin DNA bindingPPARGC1A;H2AFZ;APEX1;RARA;XBP1;INSM1B;SRF;GRHL2;NEUROG3
poly(A) RNA bindingFLNA;RBPMS;TOP3B;ALDOA;CALR;RPL14;NSA2;ADAR;TPR
protein bindingCIC;SOX15;FSHB;AKR1B10;DUSP15;DNASE1;CCDC68;FAM59A;C8orf4

HIST1H1E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H1E here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H1E.

L3MBTL1; PPP2R2B; PARP2; NCK1; MAP3K14; pre-let-7a

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