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HIST1H4E

  • Official Full Name

    HIST1H4E histone cluster 1, H4e [ Homo sapiens ]

  • Overview

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
  • Synonyms

    histone cluster 1, H4e; 4790; Ensembl:ENSG00000198518; histone H4; histone 1, H4e; H4 histone family, member J; H4/j; H4FJ;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HIST1H4E-13798H Recombinant Human HIST1H4E, GST-tagged E.coli GST 1-103a.a.
Human HIST1H4E-5525HCL Recombinant Human HIST1H4E 293 Cell Lysate HEK293 N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HIST1H4E Related Research Area

HIST1H4E involved in several pathways and played different roles in them. We selected most pathways HIST1H4E participated on our site, such as Alcoholism, Viral carcinogenesis, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H4E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AlcoholismTH;CREB3L1;HDAC9;GRB2;HDAC7A;GRIN3B;PPP1CB;H2AFV;GRIN1
Viral carcinogenesisHIST1H4G;YWHAH;HIST1H4N;RAC1;CCNE2;GTF2H4;CREB5;VAC14;CCNE1
Systemic lupus erythematosusHIST1H4H;HIST1H2BN;H2AFB2;HIST2H2BE;SSB;HIST1H2AN;C6;HIST1H3E;HIST1H2BF

HIST1H4E has several biochemical functions, for example, DNA binding, histone binding, histone demethylase activity (H4-K20 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H4E itself. We selected most functions HIST1H4E had, and list some proteins which have the same functions with HIST1H4E. You can find most of the proteins on our site.

Function Related Protein
DNA bindingTRNP1;ESR2;NKX2.1;ZNF10;SET;ZNF670;SURF6;DOT1L;FOXO1A
histone bindingPRKCBP1L;UHRF2;ANP32E;PIH1D1;CD1d1;DNAJC2;HIST2H4;HIST1H3I;BRD7
histone demethylase activity (H4-K20 specific)HIST1H4E;HIST1H4L;HIST1H4H;HIST4H4;HIST1H4F;HIST1H4K;JHDM1D;HIST1H4A;HIST2H4A
poly(A) RNA bindingRIMS2;RBM7;PTCD3;DBR1;SNTB2;FAM103A1;SRP19;DCAF13;MTDH
protein bindingZFHX3;MAPKAPK2;NADSYN1;ILKAP;TATDN1;STAG1;CDC26;THAP3;SNRNP40
protein domain specific bindingAKAP1;ANGEL1;CHMP1A;SCN5A;CALM;TFDP1;ARFIP1;TNFAIP1;CA
protein heterodimerization activityYWHAE;SMC1A;HIST1H2BO;PPP2R4;HIST1H2B7;SUPT5H;CLNS1A;SMAD1;ATP4A

HIST1H4E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H4E here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H4E.

Smad6

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