hist1h4f
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  • Official Full Name
  • HIST1H4F histone cluster 1, H4f [ Homo sapiens ]
  • Background
  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
  • Synonyms
  • histone cluster 1, H4f; 4783; Ensembl:ENSG00000198327; histone H4; histone 1, H4f; H4 histone family, member C; H4; H4/c; H4FC
Cat.#:HIST1H4F-411HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HIST1H4F Protein, His-tagged
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Cat.#:HIST1H4F-13799HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HIST1H4F, His-tagged
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Cat.#:HIST1H4F-7689MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HIST1H4F Protein
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Cat.#:HIST1H4F-5524HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human HIST1H4F 293 Cell Lysate
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Involved Pathway

Hist1h4f involved in several pathways and played different roles in them. We selected most pathways Hist1h4f participated on our site, such as Alcoholism, Viral carcinogenesis, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hist1h4f were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Alcoholism
GNB5; CALML3; HDAC5; HIST1H2BA; ATF2; HIST1H2BL; H2AFB2; SLC29A1; HIST1H3F; HAT1
Viral carcinogenesis
HDAC4; HIST2H2BE; SRF; MAPK3; TRAF1; TBPL2; CCND1; YWHAB; CDC42; HIST1H4B
Systemic lupus erythematosus
HLA-DQB1; HIST1H4M; C1R; GRIN2A; HLA-DOA; IFNG; H2AFZ; FCGR3; HIST1H2BK; H3F3A

Protein Function

Hist1h4f has several biochemical functions, for example, DNA binding, histone binding, histone demethylase activity (H4-K20 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by Hist1h4f itself. We selected most functions Hist1h4f had, and list some proteins which have the same functions with Hist1h4f. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ARID2; NR4A2B; ZNF653; PAX7B; ILF2; ZNF404; ZFP82; HINFP; ALX4; ZFP11
Function histone binding
Related Protein BAZ2A; CTSL1; UIMC1; BRD1; DAXX; SFMBT1; RBBP4; HIST1H3G; RCC1; ASF1B
Function histone demethylase activity (H4-K20 specific)
Related Protein HIST1H4J; PHF8; JHDM1D; HIST1H4H; HIST1H4F; HIST1H4E; HIST2H4A; HIST1H4L; HIST1H4A; HIST1H4I
Function poly(A) RNA binding
Related Protein CCDC9; EEF2; HHATL; DDX17; TSR1; BST2; CHD2; EBNA1BP2; RBM47; C9orf114
Function protein binding
Related Protein ZNF792; HIST2H4A; CLK2; CRBN; ATG16L1; IFITM1; USP19; RAB10; FZD7; ARL11
Function protein domain specific binding
Related Protein NFE2L2; TRIM11; ICA1L; RAB27A; KCNN2; EZR; PPP3R1; DBNL; HIST1H4N; ZFP521
Function protein heterodimerization activity
Related Protein RRAGA; HIST3H2A; SOX17; BAX; KCNIP1; ERBB2; TCF3B; CAV1; SYCP3; MAPK4

Interacting Protein

Hist1h4f has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hist1h4f here. Most of them are supplied by our site. Hope this information will be useful for your research of Hist1h4f.
Smad6