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HIST2H3C

Official Full Name

histone cluster 2, H3c
Overview

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
Synonyms

H3; H3.2; H3/M; H3F2; H3FM; H3FN; histone cluster 2, H3c; HIST2H3C;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	HIST2H3C-4813H	Recombinant Human HIST2H3C Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	HIST2H3C-114H	Recombinant Human HIST2H3C Protein, HIS-tagged	E.coli	HIS		Inquiry
Human	HIST2H3C-5515HCL	Recombinant Human HIST2H3C 293 Cell Lysate	HEK293	N/A		Inquiry
Human	HIST2H3C-3603HF	Recombinant Full Length Human HIST2H3C Protein, GST-tagged	In Vitro Cell Free System	GST	136 amino acids	Inquiry
Zebrafish	HIST2H3C-5890Z	Recombinant Zebrafish HIST2H3C	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
HIST2H3C Related Research Area

HIST2H3C involved in several pathways and played different roles in them. We selected most pathways HIST2H3C participated on our site, such as Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3, Alcoholism, Amyloid formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST2H3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	HIST4H4;KDM1A;NCOA2;KDM4C;HIST3H2BB;HIST2H3C
Alcoholism	HIST1H2BK;HIST1H2BO;PPP1CB;CALML3;GM14478;HIST2H3C;HIST2H4A;CALM1;HIST1H2AK
Amyloid formation	TTR;LTF;TGFBI;MFGE8;CEACAM21;SAA1;HIST4H4;NAT8;SEMG1
Cell Cycle	CENPI;CCNB3;CDC20;SMC1A;CENPE;CEP78;ORC4L;CDC7;TERF2
Cell Cycle, Mitotic	TUBB4A;CENPL;DCTN1;NCAPG2;ENSA;CSNK1D;SDCCAG8;CENPI;POLD3
Cellular Senescence	H1F0;HIST1H1E;TERF1;POT1A;HIST1H1A;EHMT2;ACD;RBBP7;MOV10
Cellular responses to stress	TERF2;HBXIP;CDKN2B;HSBP1A;SUZ12;RB1CC1;HTATIP;ACD;UVRAG
Chromatin modifying enzymes	KDM5B;ACTL6B;ATXN7;MCRS1;PBRM1L;WDR77;EP400;ACTL6A;MSL2B

HIST2H3C has several biochemical functions, for example, DNA binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST2H3C itself. We selected most functions HIST2H3C had, and list some proteins which have the same functions with HIST2H3C. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	DDX3X;MND1;DNASE1L2;TMPOA;ZNF333;SPO11;ZNF671;EGR2B;POGZ
histone binding	USP3;HIST1H4J;HIST1H3G;SFMBT1;DNAJC2;HIST2H4A;BRD1;SART3;HIST1H4M
protein binding	BLCAP;MT1X;CSDC2;NITR9;CACFD1;NPBWR2;TTC19;MTDH;RARRES3
protein heterodimerization activity	JAM3;MAPK4;PDX1;ANO9A;TAP1;PRPH;KCNH1;MAFGB;MYF5

HIST2H3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST2H3C here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST2H3C.

Ywhae; Ywhaz

H3 Family