HIST2H3C Protein, histone cluster 2, H3c


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Official Full Name histone cluster 2, H3c
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
Synonyms H3; H3.2; H3/M; H3F2; H3FM; H3FN; histone cluster 2, H3c; HIST2H3C
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HIST2H3C-114H Recombinant Human HIST2H3C Protein, HIS-tagged E.coli HIS
    Human HIST2H3C-4813H Recombinant Human HIST2H3C Protein, GST-tagged Wheat Germ GST
    Human HIST2H3C-5515HCL Recombinant Human HIST2H3C 293 Cell Lysate HEK293 N/A
    Zebrafish HIST2H3C-5890Z Recombinant Zebrafish HIST2H3C Mammalian Cell His

    HIST2H3C involved in several pathways and played different roles in them. We selected most pathways HIST2H3C participated on our site, such as Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3, Alcoholism, Amyloid formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST2H3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 HIST4H4; NCOA2; KDM1A; HIST3H2BB; HIST2H3C; KDM4C
    Alcoholism GRIN2D; GNG3; SHC1; HDAC9; CRH; HIST2H3A; HDAC11; HDAC10; HIST1H3E; GM14476
    Amyloid formation ODAM; SAA1; HIST2H3C; MFGE8; LTF; TGFBI; CEACAM21; CST3; NAT8; APCS
    Cell Cycle, Mitotic KIF2B; TUBGCP4; CEP135; CENPH; NEDD1; CSNK2B; NCAPD2; PDS5B; ESCO2; ODF2B
    Cellular Senescence H3F3D; HTATIP; CDK4; HIRA; LMNB1; KDM6B; ASF1A; CDKN2A; CBX8B; AGO3
    Cellular responses to stress EEF1A1; ATG9A; AGO1; TXNRD2; BAG3; EHMT2; HSPA12B; CEBPB; TXN; KIAA1967
    Chromatin modifying enzymes GATAD2A; TADA1; PADI2; SMARCC2; KAT6B; ACTL6B; C3orf75; TAF6L; HMG20B; CAPNS2

    HIST2H3C has several biochemical functions, for example, DNA binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST2H3C itself. We selected most functions HIST2H3C had, and list some proteins which have the same functions with HIST2H3C. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding UBN2B; RC3H2; LIG3; ISL1L; SYCP1; SOX32; ZFP367; ZNF404; ZFP488; HOPX
    histone binding HIST1H4A; HIST1H4F; APBB1; SERPINB1A; HIST2H4; SFMBT1; MYSM1; HIST2H4A; PHF21B; PIH1D1
    protein binding EWSR1A; MRAP; AGER; ASPSCR1; DNER; MITF; OTX2; BIN3; FLOT1; EIF3J
    protein heterodimerization activity IRAK1; ABTB2; PEF1; NTSR1; DRAP1; ERBB3; SYT16; CHUK; CUL5; H2AFJ

    HIST2H3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST2H3C here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST2H3C.

    Ywhae; Ywhaz

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