|Official Full Name||histone cluster 2, H3c|
|Background||Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.|
|Synonyms||H3; H3.2; H3/M; H3F2; H3FM; H3FN; histone cluster 2, H3c; HIST2H3C|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
HIST2H3C involved in several pathways and played different roles in them. We selected most pathways HIST2H3C participated on our site, such as Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3, Alcoholism, Amyloid formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST2H3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3||HIST4H4; NCOA2; KDM1A; HIST3H2BB; HIST2H3C; KDM4C|
|Alcoholism||GRIN2D; GNG3; SHC1; HDAC9; CRH; HIST2H3A; HDAC11; HDAC10; HIST1H3E; GM14476|
|Amyloid formation||ODAM; SAA1; HIST2H3C; MFGE8; LTF; TGFBI; CEACAM21; CST3; NAT8; APCS|
|Cell Cycle||CDC23; DULLARD; CDK11B; ORC5; GSK3AA; CCNB3; ORC1L; BRCC3; ORC4L; TERF2IP|
|Cell Cycle, Mitotic||KIF2B; TUBGCP4; CEP135; CENPH; NEDD1; CSNK2B; NCAPD2; PDS5B; ESCO2; ODF2B|
|Cellular Senescence||H3F3D; HTATIP; CDK4; HIRA; LMNB1; KDM6B; ASF1A; CDKN2A; CBX8B; AGO3|
|Cellular responses to stress||EEF1A1; ATG9A; AGO1; TXNRD2; BAG3; EHMT2; HSPA12B; CEBPB; TXN; KIAA1967|
|Chromatin modifying enzymes||GATAD2A; TADA1; PADI2; SMARCC2; KAT6B; ACTL6B; C3orf75; TAF6L; HMG20B; CAPNS2|
HIST2H3C has several biochemical functions, for example, DNA binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST2H3C itself. We selected most functions HIST2H3C had, and list some proteins which have the same functions with HIST2H3C. You can find most of the proteins on our site.
|DNA binding||UBN2B; RC3H2; LIG3; ISL1L; SYCP1; SOX32; ZFP367; ZNF404; ZFP488; HOPX|
|histone binding||HIST1H4A; HIST1H4F; APBB1; SERPINB1A; HIST2H4; SFMBT1; MYSM1; HIST2H4A; PHF21B; PIH1D1|
|protein binding||EWSR1A; MRAP; AGER; ASPSCR1; DNER; MITF; OTX2; BIN3; FLOT1; EIF3J|
|protein heterodimerization activity||IRAK1; ABTB2; PEF1; NTSR1; DRAP1; ERBB3; SYT16; CHUK; CUL5; H2AFJ|
HIST2H3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST2H3C here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST2H3C.