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HSPA12B

  • Official Full Name

    heat shock 70kD protein 12B

  • Overview

    The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family. This gene may be involved in susceptibility to atherosclerosis. Alternative splicing results in multiple transcript variants.
  • Synonyms

    HSPA12B; heat shock 70kD protein 12B; C20orf60, chromosome 20 open reading frame 60; heat shock 70 kDa protein 12B; dJ1009E24.2; C20orf60; FLJ32150; MGC131912;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSPA12B-5101H Recombinant Human HSPA12B Protein, GST-tagged Wheat Germ GST
Human HSPA12B-5359HCL Recombinant Human HSPA12B 293 Cell Lysate HEK293 N/A
Human HSPA12B-1479H Recombinant Human HSPA12B protein, His & T7-tagged E.coli His/T7 Met1~Gln217 (Accession # Q96MM6)
Human HSPA12B-5492H Recombinant Human HSPA12B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HSPA12B-3809HF Recombinant Full Length Human HSPA12B Protein, GST-tagged In Vitro Cell Free System GST 686 amino acids
Mouse HSPA12B-7901M Recombinant Mouse HSPA12B Protein Mammalian Cell His
Mouse HSPA12B-4352M Recombinant Mouse HSPA12B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HSPA12B-4352M-B Recombinant Mouse HSPA12B Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HSPA12B-3817Z Recombinant Zebrafish HSPA12B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HSPA12B Related Articles

HSPA12B involved in several pathways and played different roles in them. We selected most pathways HSPA12B participated on our site, such as Cellular response to heat stress, Cellular responses to stress, Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSPA12B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cellular response to heat stressHSPH1;NUP35;HSPA7;HSPA14;NUPL2;DNAJC7;MAPKAPK2B;HSBP1A;DPF1
Cellular responses to stressTNIK;LC3;ACD;ATG9B;WIPI1;MOV10;CDKN2D;ATG7;H3F3B.1
Regulation of HSF1-mediated heat shock responseHSPA7;RPS19BP1;HSPA13;DNAJC7;C11orf73;ST13;HSPH1;KIAA1967;DNAJB6

HSPA12B has several biochemical functions, for example, ATP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSPA12B itself. We selected most functions HSPA12B had, and list some proteins which have the same functions with HSPA12B. You can find most of the proteins on our site.

Function Related Protein
ATP bindingSUPV3L1;CDC34;EIF2AK1;UBE2T;PRKACBA;ATP8B5;KIF5B;P2RY1;HSPH1
protein bindingSLC1A1;GATA6;KCNN4;C12orf40;ZFP259;RAD52;C2orf65;CASQ2;KRT6A

HSPA12B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSPA12B here. Most of them are supplied by our site. Hope this information will be useful for your research of HSPA12B.

KRT31; KRT40; NOTCH2NL

Steagall, RJ; Rusinol, AE; et al. HSPA12B is predominantly expressed in endothelial cells and required for angiogenesis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 26:2012-2018(2006).
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