ifna4
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  • Official Full Name
  • interferon, alpha 4
  • Background
  • Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily, and are produced by a wide variety of cells types in response to challenges by foreign agents such as viruses, parasites and tumor cells.
  • Synonyms
  • IFNA4; interferon, alpha 4; interferon alpha-4; IFN alpha4a; MGC142200; Interferon alpha 4 precursor; Interferon alpha 4B; Interferon alpha 76; Interferon alpha M1; IFN-alpha-4; interferon alpha-4B; interferon alpha-76; interferon alpha-M1; INFA4; IFN-alpha4a
Cat.#:IFNA4-432HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
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Cat.#:IFNA4-1190HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 Protein, MYC/DDK-tagged
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Cat.#:IFNA4-75HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interferon, Alpha 4
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Cat.#:IFNA4-156HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
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Cat.#:IFNA4-175HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IFNA4, His tagged
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Cat.#:IFNA4-193HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
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Cat.#:IFNA4-29HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4, Fc tagged
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Cat.#:IFNA4-597HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFNA4
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Cat.#:Ifna4-122MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifna4, Fc-tagged
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Cat.#:Ifna4-157MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ifna4 Protein, His-tagged
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Cat.#:IFNA4-183MTag:GST
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifna4, His tagged
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Cat.#:Ifna4-596MTag:
Source (Host):mammalian cellsSpecies:Mouse
Product nameRecombinant Mouse Ifna4
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Cat.#:Ifng4-122MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifng4 protein, Fc-tagged
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Cat.#:Ifna4-158RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ifna4 Protein, His-tagged
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Cat.#:Ifna4-7447RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Ifna4, Fc tagged
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Cat.#:IFNA4-8840CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA4, Fc tagged
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Cat.#:IFNA4-2933HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 cell lysate
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Cat.#:IFNA4-495HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IFNA4 cell lysate
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Cat.#:IFNA4-846MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IFNA4 cell lysate
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Cat.#:IFNA4-1412RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat IFNA4 cell lysate
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Cat.#:IFNA4-989CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA4 cell lysate
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Involved Pathway

Ifna4 involved in several pathways and played different roles in them. We selected most pathways Ifna4 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ifna4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CXCR3.1; IL22; TNFRSF4; IL2RA; BMPR1A; IFNA10; IL2RB; TNFRSF10C; TNFRSF17; IL8L1
Regulation of autophagy
ATG4D; ATG16L1; ULK2; IFNA17; ATG4C; GABARAPA; ATG13; IFNA5; ULK3; ATG14
PIK-Akt signaling pathway
RAC1; IBSP; PPP2R2D; IL4R; NGFR; PDGFRA; LAMA4; FGF14; KLK1B4; GNG12
Toll-like receptor signaling pathway
TLR7; TLR4BB; MAP2K2A; IL12BA; IFNB1; RIPK1; TLR8; PIK3R3A; CCL4L2; PIK3CB
RIG-I-like receptor signaling pathway
IFNE; MAPK12; NLRX1; IFNK; IKBKG; MAPK12B; IL-8; RNF125; IFNA3; TMEM173
Cytosolic DNA-sensing pathway
IL18; IFNA5; MB21D1; TBK1; POLR3F; IFNA16; POLR3B; PYCARD; IFNPHI3; IFNA1
Jak-STAT signaling pathway
PIK3CA; PRL2; RAF1; OSMR; IL20RA; Il2; CISHB; IFNB; STAT5B; PIK3R1
Natural killer cell mediated cytotoxicity
HLA-G; KLRA8; KIR2DS3; IFNA17; NFATC1; SHC4; TNFSF10; FAS; KLRC2; PAK1
Tuberculosis
RIPK2; LAMP1; RAB5B; MAPK10; IRAK1; PIK3C3; ITGAM; ARHGEF12; IFNGR2; MRC1
Hepatitis C
MAPK9; TRAF6; RIPK1; STAT3; PPARA; CXCL8; TRADD; AKT2; AKT1; RAF1
Hepatitis B
SMAD3; RELA; IFNA17; CXCL8; NFKBIA; PTK2B; Ifna15; EGR2; MAP2K2; TBK1
Measles
OAS3; IFNA2; TNFSF10; TNFAIP3; HSPA1L; IRAK1; FASLG; TNFRSF10A; IFNA21; CCND1
Influenza A
KPNA1; ACTB; PIK3CG; HLA-DQA1; IFNA5; EIF2AK1; NUP98; HLA-DRB1; XPO1; OAS1
Herpes simplex infection
CLOCK; HLA-DPB1; HLA-DMA; TAF13; DAXX; NXF1; TP53; SRSF2; IFNA8; HLA-DRB4
Autoi
Ifna15; HLA-E; HLA-DOA; HLA-DRB5; IFNA4; TPO; HLA-DPA1; HLA-DPB1; TG; IFNA8
ne thyroid disease
H2-AA; GZMB; HLA-DPA1; HLA-G; HLA-C; IFNA7; HLA-DRB3; HLA-DQB1; IFNA17; CD80

Protein Function

Ifna4 has several biochemical functions, for example, cytokine activity, protein binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ifna4 itself. We selected most functions Ifna4 had, and list some proteins which have the same functions with Ifna4. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein GDF15; CMTM4; NDR1; Flt3l; HMGB1; IFNK; NAMPT; FLT3LG; LTA; IFNA7
Function protein binding
Related Protein MLC1; PPP4R2; CSK; PALLD; CCAR1; CNOT1; C2orf57; AKAP7; USP10; GNG5
Function type I interferon receptor binding
Related Protein GM13289; OSTN; IFNA13; IFNPHI1; IFNA3; IFNA2; GM13285; Gm13290; IFNPHI4; IFNA4

Interacting Protein

Ifna4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ifna4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ifna4.
ALDOA

Ifna4 Related Articles

Park, JH; Joo, CK; et al. Comparative Study of Tacrolimus and Bevacizumab on Corneal Neovascularization in Rabbits. CORNEA 34:449-455(2015).
Aydinoglu-Candan, O; Araz-Ersan, B; et al. Anti-interferon alpha antibodies and autoantibodies in patients with Beh double dagger et's disease uveitis treated with recombinant human interferon alpha-2a. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 253:457-465(2015).

Ifna4 Related Gene Family

Cytokines