IZUMO1 Protein, izumo sperm-egg fusion 1


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Official Full Name izumo sperm-egg fusion 1
Background The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma;membrane binding and fusion (Inoue et al., 2005 (PubMed 15759005)).
Synonyms IZUMO1; izumo sperm-egg fusion 1; izumo sperm-egg fusion protein 1; IZUMO; MGC34799; OBF; oocyte binding/fusion factor; sperm-specific protein Izumo; FLJ61440
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IZUMO1-1248HCL Recombinant Human IZUMO1 cell lysate Human Cell N/A
    Human IZUMO1-197H Recombinant Human IZUMO1, GST-tagged E.coli GST
    Human IZUMO1-2637H Recombinant Human IZUMO1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IZUMO1-8591H Recombinant Human IZUMO1, His tagged Human Cell His
    Mouse IZUMO1-8402M Recombinant Mouse IZUMO1 Protein Mammalian Cell His
    Rat IZUMO1-3133R Recombinant Rat IZUMO1 Protein Mammalian Cell His
    Rhesus Macaque IZUMO1-2323R Recombinant Rhesus monkey IZUMO1 Protein, His-tagged Mammalian Cell His

    IZUMO1 involved in several pathways and played different roles in them. We selected most pathways IZUMO1 participated on our site, such as Fertilization, Reproduction, Sperm:Oocyte Membrane Binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with IZUMO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fertilization CATSPER2; TMEM146; ADAM2; ZP3; OVGP1; ADAM20; HVCN1; CATSPER3; CATSPER1; ZP2
    Sperm:Oocyte Membrane Binding IZUMO1; IZUMO4

    IZUMO1 has several biochemical functions, for example, protein homodimerization activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IZUMO1 itself. We selected most functions IZUMO1 had, and list some proteins which have the same functions with IZUMO1. You can find most of the proteins on our site.

    Function Related Protein
    protein homodimerization activity KCNN2; NCR3; PRPS1L1; SLC14A2; TMEM192; HLA-G; CARD9; TAP1; SRM; CD2
    receptor binding SNX17; PSPN; INSL3; PVRL1; NOS2; FGF12B; PCSK1N; HLA-F; NRG4; PVR

    IZUMO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IZUMO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IZUMO1.

    Mizukami, M; Tokunaga, H; et al. Highly efficient production of VHH antibody fragments in Brevibacillus choshinensis expression system. PROTEIN EXPRESSION AND PURIFICATION 105:23-32(2015).
    Inoue, N; Hamada, D; et al. Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion. DEVELOPMENT 140:3221-3229(2013).

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