izumo1
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  • Official Full Name
  • izumo sperm-egg fusion 1
  • Background
  • The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma;membrane binding and fusion (Inoue et al., 2005 (PubMed 15759005)).
  • Synonyms
  • IZUMO1; izumo sperm-egg fusion 1; izumo sperm-egg fusion protein 1; IZUMO; MGC34799; OBF; oocyte binding/fusion factor; sperm-specific protein Izumo; FLJ61440
Cat.#:IZUMO1-2637HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human IZUMO1 Protein, MYC/DDK-tagged
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Cat.#:IZUMO1-197HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IZUMO1, GST-tagged
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Cat.#:IZUMO1-8591HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IZUMO1, His tagged
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Cat.#:IZUMO1-8402MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IZUMO1 Protein
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Cat.#:IZUMO1-3133RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IZUMO1 Protein
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Cat.#:IZUMO1-2323RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IZUMO1 Protein, His-tagged
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Cat.#:IZUMO1-1248HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IZUMO1 cell lysate
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Involved Pathway

IZUMO1 involved in several pathways and played different roles in them. We selected most pathways IZUMO1 participated on our site, such as Fertilization, Reproduction, Sperm:Oocyte Membrane Binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with IZUMO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fertilization
CATSPER2; CATSPERB; CATSPER1; CATSPERG1; Acr; ADAM21; ADAM30; ZP2; CATSPERG2; ADAM20
Reproduction
CATSPERG2; ZP3; CATSPERG1; CATSPER2; CATSPER3; ADAM2; CATSPER1; IZUMO4; HVCN1; ADAM21
Sperm:Oocyte Membrane Binding
IZUMO1; IZUMO4

Protein Function

IZUMO1 has several biochemical functions, for example, protein homodimerization activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IZUMO1 itself. We selected most functions IZUMO1 had, and list some proteins which have the same functions with IZUMO1. You can find most of the proteins on our site.
Function
Related Protein
Function protein homodimerization activity
Related Protein HLA-G; WRN; IDE; GSS; TSC2; SRM; ADSSL1; DCK; PVRL3B; SLIT2
Function receptor binding
Related Protein MSN; PLAUR; WNT5B; TENM2; PICK1; TNFSF15; NUDT19; SERPINE2; STOML2; HFE

IZUMO1 Related Articles

Mizukami, M; Tokunaga, H; et al. Highly efficient production of VHH antibody fragments in Brevibacillus choshinensis expression system. PROTEIN EXPRESSION AND PURIFICATION 105:23-32(2015).
Inoue, N; Hamada, D; et al. Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion. DEVELOPMENT 140:3221-3229(2013).