Junb Protein, jun B proto-oncogene


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Official Full Name jun B proto-oncogene
Background The JunB transcrIPPtion factor, also known as JunB proto-oncogene, JunB oncogene, transcrIPPtion factor JunB, and transforming protein JunB, is a basic region leucine zIPPer DNA-binding protein, and a member of the Jun family of proteins, which also inclu
Synonyms JUNB; jun B proto-oncogene; transcription factor jun-B; activator protein 1; AP-1
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Junb-1253M Recombinant Mouse Junb Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human JUNB-218H Recombinant Human JUNB, GST-tagged E.coli GST
    Human JUNB-886HCL Recombinant Human JUNB cell lysate N/A
    Mouse JUNB-8439M Recombinant Mouse JUNB Protein Mammalian Cell His
    Rat JUNB-3147R Recombinant Rat JUNB Protein Mammalian Cell His
    Rhesus Macaque JUNB-2336R Recombinant Rhesus monkey JUNB Protein, His-tagged Mammalian Cell His

    Junb involved in several pathways and played different roles in them. We selected most pathways Junb participated on our site, such as ATF-2 transcription factor network, Calcineurin-regulated NFAT-dependent transcription in lymphocytes, Calcium signaling in the CD4+ TCR pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Junb were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ATF-2 transcription factor network GADD45A; DUSP10; KCNA3; JUND; CDK4; JUNB; POU2F1; DDIT3; CSRP2; CREB1
    Calcineurin-regulated NFAT-dependent transcription in lymphocytes BATF3; POU2F1; CSF2; IKZF1; EGR3; CDK4; EGR4; JUNB; EGR1; IRF4
    Calcium signaling in the CD4+ TCR pathway AKAP5; CSF2; RCAN2; CHP; POU2F1; RCAN1; BATF3; FKBP1A; JUNB
    Corticotropin-releasing hormone CYP21A2; CASP12; CRHR1; TRIM28; CYP11A1; ADRBK2; KRT14; PARP1; IVL; JUNB
    Downstream signaling in naive CD8+ T cells EGR4; EGR1; JUNB; EOMES
    Gene Expression ZNF394; IPO8; SF3A3; ALKBH8; ZNF302; CLNS1A; ZNF18; HNRNPA0L; EIF2C3; LSM11
    Generic Transcription Pathway ZNF433; ZNF500; ZNF577; ZFP30; ZNF565; ZNF264; ZNF460; ZNF222; ZNF287; MED20
    IL6-mediated signaling events CRP; JUNB; LMO4; PIAS3

    Junb has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Junb itself. We selected most functions Junb had, and list some proteins which have the same functions with Junb. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding AKAP8L; ADNP2A; ZNF227; ZHX1; TDP2B; YEATS4; PROX1; ZBTB1; RNF11; TIGD6
    RNA polymerase II core promoter proximal region sequence-specific DNA binding PLAG1; TFE3A; EP300; ZIC1; HOXA7; H2AFZ; CEBPA; HHEX; TXK; ATF7
    RNA polymerase II transcription factor activity, sequence-specific DNA binding EPAS1; FLI1; SIM1A; FOXP1; EF1; FOXO4; ZNF174; PHB; ERG; SOX8
    protein binding TTC30B; FBLIM1; NAT10; STAG2; PTK7; KRT16; OIP5; FMO4; CCNA2; INPP5B
    transcription coactivator activity MED26; NEUROG3; NPAT; GTF2F1; Ankar; SAP130; MAK; ECD; TFDP1A; SNW1
    transcription corepressor activity SAP30; ATF3; TBL1XR1B; TBL1X; SKOR1; TRIM28; CREG1; KDM5B; PFDN5; WTIP
    transcription factor binding PRKDC; POU5F1; HAND1; CCND1; HDAC4; CTNNB1; TFDP2; PIAS1; NFATC3; PIANP
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding AKNA; EBF1; GLIS2; TP53; NCOA3; ZFP750; ETV1; NR4A1; FOXJ2; ETV6

    Junb has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Junb here. Most of them are supplied by our site. Hope this information will be useful for your research of Junb.


    Atsaves, V; Lekakis, L; et al. The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK plus anaplastic large cell lymphoma. BRITISH JOURNAL OF HAEMATOLOGY 167:514-523(2014).
    Perdomo, MF; Hosia, W; et al. Human serum protein enhances HIV-1 replication and up-regulates the transcription factor AP-1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:17639-17644(2012).

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