KIF18A
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Official Full Name
kinesin family member 18A -
Overview
KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use;hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 (PubMed;15878648)). -
Synonyms
KIF18A;kinesin family member 18A;kinesin-like protein KIF18A;DKFZP434G2226;MS-KIF18A
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- E.coli
- Bacteria
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF18A-361H | Recombinant Human KIF18A, GST-tagged | E.coli | Human | GST | 1-279aa | |
| KIF18A-263H | Recombinant Human KIF18A Protein, His-tagged | E.coli | Human | His | Met1~Lys453 | |
| KIF18A-12H |
Recombinant Human KIF18A Protein, His-tagged
|
Bacteria | Human | His | 1-374 aa |
|
| KIF18A-1049H | Recombinant Human KIF18A | Mammalian Cells | Human | His |
|
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| KIF18A-10579Z | Recombinant Zebrafish KIF18A | Mammalian Cells | Zebrafish | His |
|
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| KIF18A-4299C | Recombinant Chicken KIF18A | Mammalian Cells | Chicken | His |
|
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| KIF18A-4952HCL | Recombinant Human KIF18A 293 Cell Lysate | HEK293 | Human | Non |
|
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| KIF18A-3213H | Recombinant Human KIF18A Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
|
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| KIF18A-3213H-B | Recombinant Human KIF18A Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
Involved Pathway
KIF18A involved in several pathways and played different roles in them. We selected most pathways KIF18A participated on our site, such as Adaptive Immune System,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF18A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Factors involved in megakaryocyte development and platelet production | DOCK6,MAFGA,KIF2B,HBG2,GATA5,MGC173646,KIF2A,CABLES2,HBBE1.1,OSTN |
| Immune System | KLRF1,EGR1,TRIM26,CD200R4,DEFB4B,ASB8,IRF4,GRAP2A,ASB13,UBE2E3 |
| Cell cycle | UIMC1,THRSP,E2F5,E2F4,ANAPC4,NDEL1B,GINS1,ANAPC11,SMC4,CDC25B |
| M Phase | DSN1,SPC25,PDS5B,NIPBLA,DULLARD,MCPH1,GORASP1,SET,INCENP,ENSAA |
| Kinesins | KIF4,KIF2A,KIF2C,KIF20A,KIFAP3,KIF9,KIF3C,KIF22,KIF5A,KIF15 |
| Cell Cycle, Mitotic | ZWILCH,NSL1,RCC2,CENPK,CDK5RAP2,MAPRE1B,TMPO,NDEL1,NUPL2,CSNK2A1 |
| Hemostasis | CEACAM8,PRKCHB,KIF9,DGKB,GATA5,DOCK7,MAFGB,ANXA2,CFHL1,ANGPT2A |
| Adaptive Immune System | FBXO3,DZIP3,TRAT1,STIM1B,MGC174857,DYNC1I1,ICAM4,HLA-DQB2,DCTN1,PAG1 |
Protein Function
KIF18A has several biochemical functions, for example, ATP binding,ATP-dependent microtubule motor activity, plus-end-directed,actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF18A itself. We selected most functions KIF18A had, and list some proteins which have the same functions with KIF18A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP-dependent microtubule motor activity, plus-end-directed | KIF3B,KIF14,KIF1B,KIF5B,KIF3A,KIF11,KIF16B,KIF5C,KIF19,KIF20B |
| ATP binding | DDX19A,ATP11A,GLULB,TCP1,PDS5B,MAPKAPK5,ACACA,CLK4,P2RX4A,G3BP1 |
| ubiquitin binding | DNAJC2,IDE,KCNS1,BCL10,SQSTM1,FAF1,CRY1,RBCK1,TOM1L1,NBR1 |
| microtubule binding | MAP6D1,APC,CHP,DCX,CCDC88A,PAFAH1B1B,PLK1,DNM2,PAFAH1B1,KIF13B |
| microtubule plus-end binding | DST,MAPRE1,CLASP1A,STIM1,CLASP1,CLIP2,APC,KIF2C,CLIP1 |
| protein binding | SYT6,Trf,MAF,CPT1C,UBQLN1,SPEF2,PRDM13,SHC4,NCLN,BEND7 |
| actin binding | HIP1R,WASF3,WASF3B,ACE,CAPZA3,MYH15,RP2,FMN2,FHOD1,MYO1G |
Interacting Protein
KIF18A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF18A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF18A.
ANAPC4;NFKBIB;PPP1CA;NCOR1;TCF3;PPP1CC;TTC3;CSE1L;Ppp1cb;FOXM1;PSMD5;C18orf21;GKAP1;Kif18b;SAMD1;Kif1bp;CASC5;Cdc16;EME1
Resources
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References
- Zusev, M; Benayahu, D; et al. New Insights on Cellular Distribution, Microtubule Interactions and Post-Translational Modifications of MS-KIF18A. JOURNAL OF CELLULAR PHYSIOLOGY 217:618-625(2008).
- Luboshits, G; Benayahu, D; et al. MS-KIF18A, a kinesin is associated with estrogen receptor. JOURNAL OF CELLULAR BIOCHEMISTRY 100:693-702(2007).
