KIF1B
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Official Full Name
kinesin family member 1B -
Overview
This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008] -
Synonyms
KIF1B;kinesin family member 1B;KLP;CMT2;CMT2A;CMT2A1;HMSNII;NBLST1;kinesin-like protein KIF1B;kinesin superfamily protein KIF1B
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF1B-364H | Recombinant Human KIF1B, His-tagged | E.coli | Human | His | C-term-350aa | |
| KIF1B-3252R | Recombinant Rat KIF1B Protein | Mammalian Cells | Rat | His |
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| KIF1B-9732Z | Recombinant Zebrafish KIF1B | Mammalian Cells | Zebrafish | His |
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| KIF1B-4951HCL | Recombinant Human KIF1B 293 Cell Lysate | HEK293 | Human | Non |
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| KIF1B-2908R | Recombinant Rat KIF1B Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| KIF1B-2908R-B | Recombinant Rat KIF1B Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
KIF1B involved in several pathways and played different roles in them. We selected most pathways KIF1B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KIF1B has several biochemical functions, for example, ATP binding,ATP-dependent microtubule motor activity, plus-end-directed,ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF1B itself. We selected most functions KIF1B had, and list some proteins which have the same functions with KIF1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule motor activity | KIF26A,KIF2A,KIFC2,KIF27,CENPE,KIF4A,DNAH5,KIF3C,KIF13B,KIF14 |
| kinesin binding | KCNC1,SYBU,KIFAP3B,AP1G1,KLC2,ATCAY,NEFH,IFT88,TOR1A,ARHGEF10 |
| microtubule binding | MAPT,KIAA1128,CCDC88A,RGS14,GOLSYN,VPS41,ARL3,DNM2,KIF27,MAPRE3B |
| protein binding | FASTKD3,DAPP1,PEX1,RCC1,SERPINB1A,PEPD,COL10A1,SMAD3A,C21orf56,TMA16 |
| ATP binding | ULK3,PRKACBB,EIF2AK2,GCLC,HSPA6,LATS1,ENTPD8,ABCA6,KIF4A,TWF2 |
| ATPase activity | ACTC1,KIF21A,HSP90AA1,ABCC8,ABCC12,IDE,KIF12,MYH8,ASNA1,MLH1 |
| ATP-dependent microtubule motor activity, plus-end-directed | KIF17,KIF16B,KIF3A,KIF18A,KIF1C,KIF19,KIF3B,KIF18B,KIF14,KIF5A |
Interacting Protein
KIF1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF1B here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF1B.
YWHAG;CLASP1;SIAH1;YWHAH;DYSF;PARK7;TFCP2;CERS2;LAMTOR5;p29991-pro_0000037941;p29991-pro_0000308465;PGM1;EEF1A1
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References
- Seog, DH; Han, J; et al. Sorting nexin 17 interacts directly with kinesin superfamily KIF1B beta protein. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY 12:199-204(2008).
