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KIF22

  • Official Full Name

    kinesin family member 22

  • Overview

    The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance.
  • Synonyms

    KIF22; kinesin family member 22; kinesin like 4 , KNSL4; kinesin-like protein KIF22; Kid; OBP 1; OBP 2; A 328A3.2; KIF 22; Kinesin like 4; Kinesin like DNA binding protein; Kinesin like DNA binding protein pseudogene; Kinesin like protein 4; Kinesin like protein KIF22; KNSL 4; KNSL4; OBP; OBP1; OBP2; Origin of plasmid DNA replication binding protein; OriP binding protein; OTTHUMP00000123406; kinesin-like 4; kinesin-like protein 4; kinesin-like DNA-binding protein pseudogene; origin of plasmid DNA replication-binding protein; OBP-1; OBP-2; A-328A3.2;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KIF22-927HCL Recombinant Human KIF22 cell lysate N/A
Human KIF22-3109H Recombinant Human KIF22 protein, His-tagged E.coli His 4 - 353 aa
Mouse KIF22-8634M Recombinant Mouse KIF22 Protein Mammalian Cell His
Mouse KIF22-4811M Recombinant Mouse KIF22 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse KIF22-4811M-B Recombinant Mouse KIF22 Protein Pre-coupled Magnetic Beads HEK293
Rat KIF22-3254R Recombinant Rat KIF22 Protein Mammalian Cell His
Rat KIF22-2910R Recombinant Rat KIF22 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KIF22-2910R-B Recombinant Rat KIF22 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish KIF22-6328Z Recombinant Zebrafish KIF22 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KIF22 Related Articles
  • KIF22 Related Gene Family

KIF22 involved in several pathways and played different roles in them. We selected most pathways KIF22 participated on our site, such as Adaptive Immune System, Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemKLHL20;UBE2E3;PVRL2L;NRG4;RASGRP2;KLRF1;RACGAP1;KIF4A;NCR3LG1
Factors involved in megakaryocyte development and platelet productionKLC3;HBD;GATA1A;CABLES1;DOCK10;MAFGB;SH2B3;H3F3D;H3F3B.1
HemostasisF9A;KIFAP3;KIF2B;HBD;MMRN2A;LOC100514666;HBB-Y;DOCK8;KIF4
Immune SystemNA;TRIM6;TRIM29;HECTD3;DEFA1;ACTR2B;PIK3AP1;PELI2;SH3RF1
KinesinsKIFC1;KIF4A;KIF2A;KIF5A;KIF22;RACGAP1;KIF18A;CENPE;KIF2B
MHC class II antigen presentationKIF3C;KIFAP3;DYNC1LI2;MGC174152;AP1S3A;KIF11;CTSC;CTS7;ACTR1B

KIF22 has several biochemical functions, for example, ATP binding, ATPase activity, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF22 itself. We selected most functions KIF22 had, and list some proteins which have the same functions with KIF22. You can find most of the proteins on our site.

Function Related Protein
ATP bindingEIF4A1;KIF2A;SUCLA2;CHD4;AK5;MAP2K3;ATP7B;UBE2D1A;ABCG3
ATPase activityNSF;HAND2;ABCB6;RNF213;ABCA1B;RHOBTB3;VPS4A;ATAD1;PSMC2
DNA bindingSOX1B;CLOCKA;YY1;ORC1L;CHD4;POU2F1A;HIST1H2BA;SOX12;NFIL3
microtubule bindingSKA1;JAKMIP1;MAP1LC3C;GAS2L1;SPAG8;KIF5AA;RAB11A;CRIPT;KRIT1
microtubule motor activityKIF20A;DYNC1I2;APPBP2;KIF4A;KLC1;DNAIC2;PROL1;CENPE;KIF7
protein bindingHMGA2;HERPUD1;MAGEA2B;BTG1;TMEM149;PDCL;SNTB2;TFDP1;EHD2

KIF22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF22 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF22.

CRK; SVIL; GDF9; ATXN1; IMMT; PJA1; PSEN2; KPNA3; KPNA4; BCL2L11; MARCH6; MPDZ; CD2BP2; C4B; CCNB1; COX5A; RPL10; FUS; STAT6; LIMS1

Albracht, CD; Rank, KC; et al. Kinesin-2 KIF3AB Exhibits Novel ATPase Characteristics*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:27836-27848(2014).
Przybyl, J; Sciot, R; et al. Metastatic potential is determined early in synovial sarcoma development and reflected by tumor molecular features. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 53:505-513(2014).
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