kif22
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  • Official Full Name
  • kinesin family member 22
  • Background
  • The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance.
  • Synonyms
  • KIF22; kinesin family member 22; kinesin like 4 , KNSL4; kinesin-like protein KIF22; Kid; OBP 1; OBP 2; A 328A3.2; KIF 22; Kinesin like 4; Kinesin like DNA binding protein; Kinesin like DNA binding protein pseudogene; Kinesin like protein 4; Kinesin like protein KIF22; KNSL 4; KNSL4; OBP; OBP1; OBP2; Origin of plasmid DNA replication binding protein; OriP binding protein; OTTHUMP00000123406; kinesin-like 4; kinesin-like protein 4; kinesin-like DNA-binding protein pseudogene; origin of plasmid DNA replication-binding protein; OBP-1; OBP-2; A-328A3.2
Cat.#:KIF22-8634MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse KIF22 Protein
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Cat.#:KIF22-3254RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KIF22 Protein
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Cat.#:KIF22-6328ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KIF22
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Cat.#:KIF22-927HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human KIF22 cell lysate
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Involved Pathway

KIF22 involved in several pathways and played different roles in them. We selected most pathways KIF22 participated on our site, such as Adaptive Immune System, Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
MKRN1; SRMS; MALT1; B2ML; CTSB; TRIM50; RNF34; KLRB1F; PJA2; LILRA2
Factors involved in megakaryocyte development and platelet production
D-AKAP2; DOCK1; DOCK2; GATA1A; KIF2A; MFN1; MAFGA; DOCK10; KIF3B; KIF2B
Hemostasis
CABLES2; ABHD6B; HBE1; DOCK9; MYB; AKAP1; HBBE2; KIF3B; APOA1B; ITPK1
Immune System
PJA1; WASF2; KIFAP3; Mill2; SIGLEC14; DEFB104A; NLRC5; EVL; CD300E; CD300LH
Kinesins
RACGAP1; KIF9; KIF2A; KLC3; KIFC1; KIF22; KIF15; CENPE; KIF11; KIF18A
MHC class II antigen presentation
CTSLL; KIF3B; OSBPL1A; DCTN6; IFI30; MGC174152; KIF11; DYNC1I1; ACTR1B; MGC174857

Protein Function

KIF22 has several biochemical functions, for example, ATP binding, ATPase activity, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF22 itself. We selected most functions KIF22 had, and list some proteins which have the same functions with KIF22. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein LCK; ABCC3; AXL; RUNX2B; PI4KB; ATP4A; ATP11A; SLKA; PSMC1A; ROCK2A
Function ATPase activity
Related Protein IDE; MYO9B; ABCG5; ABCB6; ATAD2B; KIF2B; ABCB4; ABCG2B; HSPA1B; HLTF
Function DNA binding
Related Protein FANCI; DNASE1L3; SOS1; PAX2B; ZFP326; PHOX2BB; TSHZ1; DTD1; ZNF571; APP
Function microtubule binding
Related Protein PAFAH1B1B; PAFAH1B1; JAKMIP1; SGIP1; KIF18A; MID2; SNCA; CENPE; CETN2; KIF2A
Function microtubule motor activity
Related Protein KIF20B; KIF3B; KIF2C; DYNC1LI1; KIF22; KIF5AA; DYNC1H1; DNHD1; DYNC1I1; KIF21A
Function protein binding
Related Protein CUEDC2; RBX1; ALS2CR11; EFCAB11; PLD1; TMEM43; APLP2; NEFL; SALL2; ZNF263

Interacting Protein

KIF22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF22 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF22.
CRK; SVIL; GDF9; ATXN1; IMMT; PJA1; PSEN2; KPNA3; KPNA4; BCL2L11; MARCH6; MPDZ; CD2BP2; C4B; CCNB1; COX5A; RPL10; FUS; STAT6; LIMS1

KIF22 Related Articles

Albracht, CD; Rank, KC; et al. Kinesin-2 KIF3AB Exhibits Novel ATPase Characteristics*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:27836-27848(2014).
Przybyl, J; Sciot, R; et al. Metastatic potential is determined early in synovial sarcoma development and reflected by tumor molecular features. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 53:505-513(2014).

KIF22 Related Gene Family

Kinesins (KIF)