kif2c
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  • Official Full Name
  • kinesin family member 2C
  • Background
  • The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. [provided by RefSeq, Jul 2008]
  • Synonyms
  • KIF2C; kinesin family member 2C; MCAK; CT139; KNSL6; kinesin-like protein KIF2C; kinesin-like 6; kinesin-like protein 6; mitotic centromere-associated kinesin;
Cat.#:KIF2C-372HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KIF2C, GST-tagged
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Cat.#:KIF2C-6456ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KIF2C
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Cat.#:KIF2C-4946HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human KIF2C 293 Cell Lysate
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Involved Pathway

KIF2C involved in several pathways and played different roles in them. We selected most pathways KIF2C participated on our site, such as Adaptive Immune System, Aurora B signaling, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
BTLA; UBE2U; WWP1; FRS2A; FBXO27; ASB6; KIF2B; CRTAM; TREML1; NCR3LG1
Aurora B signaling
KIF2C; NDC80; DES; TACC1; SGOL1; AURKC; CENPA; PEBP1; KIF20A; NCAPD2
Cell Cycle
TUBB4B; CEP63; CCND2A; ACD; YWHAG; SKP2; APITD1; CDKN1BA; CEP70; NCAPH
Cell Cycle, Mitotic
NUDC; STIL; NIPBL; LIN9; TUBG2; POLD3; SETB; GORASP1; MAPRE1A; CENPH
Factors involved in megakaryocyte development and platelet production
GATA2A; DOCK6; KIF15; H3F3D; AKAP1; PHF21A; BA1; NFE2; BA1L; LRRC16A
Hemostasis
FN1B; KCNMB1; RHOB; IRF2A; KIF2A; PROCR; CFHL4; MAFGA; HBBE1.1; KIF11
Immune System
KIR2DS2; CFHL2; DEFB129; DEFA3; SIGLEC8; TREML1; RNF14; SIGLEC15; DZIP3; BAIAP2
Kinesins
KIF11; KIF2A; KIF20A; KLC3; KIF26A; KIF3C; KIF15; KIF18A; KIF3B; KIF2C

Protein Function

KIF2C has several biochemical functions, for example, ATP binding, ATPase activity, centromeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF2C itself. We selected most functions KIF2C had, and list some proteins which have the same functions with KIF2C. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PAK7; NAIP1; PEBP1; NLRP9C; SNRK; ATAD5; FLAD1; PRPF4BA; ITPKA; PRKDC
Function ATPase activity
Related Protein ABCB6A; DNAHC8; DNAH11; KIF4A; MYO19; DNAH5; KIF20A; SWSAP1; HAND2; ABCG2B
Function centromeric DNA binding
Related Protein CENPC1; MSH2; ZW10; KIF2C; CENPB; MLH3; MSH3
Function microtubule motor activity
Related Protein KIF25; KIF3CB; DYNLRB2; KIFC3; SMC3; KIF5C; KIF5B; KLC4; KIF13B; KIF7
Function microtubule plus-end binding
Related Protein CLASP1A; APC; DST; CLIP1; KIF2C; STIM1; KIF18A; CLASP1; CLIP2; MAPRE1
Function protein binding
Related Protein MAPT; NDNL2; PNMA2; WBP1L; USP14; PVRL4; PRAC; HHIPL2; SNX18; CAMK2G

Interacting Protein

KIF2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF2C here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF2C.
MAPRE1; MTUS2; VHL; CSNK2B; ZNF566; KIF2A; KIF2A; SRGAP3; WDR62; CENPB; RPL7; VCAM1

KIF2C Related Gene Family

Kinesins (KIF)