kif3a
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  • Official Full Name
  • kinesin family member 3A
  • Background
  • Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.
  • Synonyms
  • KIF3A; kinesin family member 3A; FLA10; KLP-20; kinesin-like protein KIF3A; kinesin family protein 3A; microtubule plus end-directed kinesin motor 3A;
Cat.#:KIF3A-373HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KIF3A, GST-tagged
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Cat.#:KIF3A-8643MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse KIF3A Protein
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Cat.#:KIF3A-2331CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken KIF3A
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Cat.#:KIF3A-2377ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KIF3A
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Cat.#:KIF3A-930HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human KIF3A cell lysate
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Involved Pathway

KIF3A involved in several pathways and played different roles in them. We selected most pathways KIF3A participated on our site, such as Activation of SMO, Adaptive Immune System, Assembly of the primary cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of SMO
EFCAB7; ADRBK1; SETD6; IQCE; EVC2; BOC; CDON; EVC; KIF3A; GAS8
Adaptive Immune System
FGF10B; PJA2; ASB6; FBXO27; RAPGEF3; STIM1B; AP2M1; FBXO17; KIR2DS2; TRIM41
Assembly of the primary cilium
RAB3IP; KIF3A; KIF3C; KIFAP3B; IFT52; CNGA5; HAUS2; ATAT1; FGFR1OP; OFD1
Endochondral Ossification
CTSL2; ADAMTS5; ADAMTS1; COL10A1A; MMP13; PTHLHA; CDKN1C; NKX3-2; SERPINH1; IFT88
Factors involved in megakaryocyte development and platelet production
AKAP1; KIF11; MAFGA; OSTN; BA2; DOCK2; BA1L; KIF4A; KIF5B; HBD
Hedgehog off state
IFT172; INTU; TTC21B; GPR161; KIF7; IFT88; IFT122; BBS13; TULP3; RPGRIP1L
Hedgehog on state
GPR161; EVC2; IQCE; RPGRIP1L; IFT172; CDON; EFCAB7; SPOPL; BOC; KIF7
Hedgehog signaling events mediated by Gli proteins
IFT88; CSNK1G2; MTSS1; CSNK1G3; SAP18; SPOP; SAP30; SIN3B; KIF3A; LGALS3

Protein Function

KIF3A has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF3A itself. We selected most functions KIF3A had, and list some proteins which have the same functions with KIF3A. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PKM; BCR; PAICS; SRPK2; YRK; UPF1; CHKA; TLK2; ITGB1BP3; MUSK
Function ATP-dependent microtubule motor activity, plus-end-directed
Related Protein KIF18B; KIF1C; KIF3A; KIF11; KIF17; KIF5AA; KIF5A; KIF1B; KIF14; KIF3B
Function microtubule binding
Related Protein EML1; RAB11A; PRNP; CEP57; APC; SYBU; KIF23; CAMSAP1B; KIF1C; BCL2L11
Function protein binding
Related Protein SPATA13; RASSF1; AGO1; SLC26A6; TNFRSF1A; NAIF1; PELO; RNF43; PPP1R12B; CD58
Function spectrin binding
Related Protein ANK1; CAMSAP1; CAMSAP1L1; GNB1; PTPRN; USH1C; PDE6G; GBP1; DYNC1I1; USH1G

Interacting Protein

KIF3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF3A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF3A.
KIFAP3; USP7; RAB11FIP5; TULP3; ARRB2; GRB2; NEK1; PLEKHA5; DISC1; KIF3C; GAK; KIF3B; Kif3c

KIF3A Related Articles

Contini, M; Lin, B; et al. Synaptic Input of ON-Bipolar Cells onto the Dopaminergic Neurons of the Mouse Retina. JOURNAL OF COMPARATIVE NEUROLOGY 518:2035-2050(2010).
Brown, CL; Maier, KC; et al. Kinesin-2 is a motor for late endosomes and lysosomes. TRAFFIC 6:1114-1124(2005).

KIF3A Related Gene Family

Kinesins (KIF)