| Official Full Name | kinesin family member 3B |
| Background | The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily. |
| Synonyms | KIF3B; kinesin family member 3B; kinesin-like protein KIF3B; KIAA0359; HH0048; KIF3B_HUMAN; Kinesin like protein KIF3B; Microtubule plus end directed kinesin motor 3B; Microtubule plus end-directed kinesin motor 3B; Similar to Mouse kinesin KIF3B; OTTHUMP00000030588 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
KIF3B involved in several pathways and played different roles in them. We selected most pathways KIF3B participated on our site, such as Adaptive Immune System, Assembly of the primary cilium, Factors involved in megakaryocyte development and platelet production, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | UBE2E3; MAPKAP1; MICA; SPSB4; BTLA; CD300LH; ASB3; STIM1B; DNM2; PDPK1A |
| Assembly of the primary cilium | CLUAP1; TTC8; BBS7; ARF4; NPHP4; IFT74; BBS9; CSNK1D; DYNLRB1; MAPRE1B |
| Factors involved in megakaryocyte development and platelet production | KIF5B; KIF2C; LRRC16A; MAFGB; EHD1; HBE1; KIF11; KIF5A; KIF4; KIF18A |
| Hemostasis | NADL1.1; HBE1; KIF18A; KIF9; GAS6; GLG1B; PRTN3; DOCK2; BRPF3; CFD |
| Immune System | FBXO17; DEFB129; ACTR1B; AP1S1; RNF220; GBP6; CD300LH; CTSD; KLRG1; HLA-DQB2 |
| Intraflagellar transport | TRAF3IP1; DYF-1; TCTEX1D2; IFT52; IFT-20; TTC26; TRIP11; KIF3C; IFT74; IFT88 |
| Kinesins | KIF3C; KLC3; KIFAP3; KIF4; KIF9; KIF4A; KIF2A; KIF26A; KIF15; KIFC1 |
| MHC class II antigen presentation | KIF22; OSBPL1A; MGC174152; KLC3; FAM49BA; CTSE; CTSC; CTSLL; RACGAP1; KIF11 |
KIF3B has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, Rho GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF3B itself. We selected most functions KIF3B had, and list some proteins which have the same functions with KIF3B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | WRN; DNAJA3; SCYL2; BRIP1; MYLK3; MADD; PIK3C2B; MST1R; OASL; DCLK1A |
| ATP-dependent microtubule motor activity, plus-end-directed | KIF1C; KIF5C; KIF5A; KIF3A; KIF18B; KIF11; KIF17; KIF20B; KIF18A; KIF1B |
| Rho GTPase binding | CSDA; INF2; FLNA; KIF3B; DIAPH1; DAPK3; PFN1; ANTXR2A; DOCK9; DAAM1B |
| microtubule binding | KIF7; POLB; KIF3A; KIF2B; FAM154A; KIF14; MAP1LC3C; ARL3; GAS2L1; PRC1A |
| microtubule motor activity | KIF2B; KIF2A; SMC3; CENPE; DNHD1; KLC1B; KIF1B; KIF5AA; DNAH14; DYNC2H1 |
| protein binding | DDI1; DGCR8; SMC4; FBF1; C21orf7; TOM1; BCL2L12; MAGEE1; CDKAL1; PARVB |
KIF3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF3B here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF3B.
KIFAP3; ARHGEF10; LMO2; LMO4; Mphosph9; Hax1; Magoh; Sptlc2; KIF3A; Homer1
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