|Official Full Name||kinesin family member 5A|
|Background||This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10.|
|Synonyms||KIF5A; kinesin family member 5A; spastic paraplegia 10 (autosomal dominant) , SPG10; kinesin heavy chain isoform 5A; D12S1889; MY050; NKHC; KIF5A variant protein; neuronal kinesin heavy chain; kinesin heavy chain neuron-specific 1; kinesin, heavy chain, n|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KIF5A involved in several pathways and played different roles in them. We selected most pathways KIF5A participated on our site, such as Adaptive Immune System, Dopaminergic synapse, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||RNF34; GRAP2B; RNF220; OSBPL1A; TRIM63; MAP3K8; KLHL21; PJA2; DCTN2; EGFR|
|Dopaminergic synapse||TH; GNG3; PRKCG; ARNTL; PPP1CC; PPP2R2A; DRD1; PRKACA; PPP2R2D; GNAS|
|Endocytosis||ZFYVE20; KIF5A; SH3GLB1A; MET; CHMP3; SH3GLB2; ARR3B; CYTH4; HLA-E; SH3GL1A|
|Factors involved in megakaryocyte development and platelet production||PHF21A; H3F3B.1; KIF2B; H3F3D; CABLES2; KLC3; OSTN; IRF1B; KIF3B; MFN1|
|Hemostasis||TFA; SERPINE2; OSTN; DOCK7; SPARC; SERPINB8; VPS45; GAS6; RHOGA; PDPN|
|Immune System||ABI2; UBE2E3; WSB1; DEFA6; HUWE1; FBXO17; FBXO27; RNF216; RNF135; IFITM2|
|Insulin processing||SLC30A8; PCSK1; PCSK2; EXOC5; EXOC8; SLC30A6; EXOC1; KIF5A; EXOC3; EXOC6|
|Kinesins||KIF2B; KIF5A; KIF9; KIF18A; RACGAP1; KIF15; KIF2A; KIF26A; KIF22; KIF2C|
KIF5A has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF5A itself. We selected most functions KIF5A had, and list some proteins which have the same functions with KIF5A. You can find most of the proteins on our site.
|ATP binding||ABCD3B; ABL2; KCNJ10; MYH7; MUSK; IFIH1; STK35L; NMNAT3; EIF4A1B; KIF1B|
|ATP-dependent microtubule motor activity, plus-end-directed||KIF11; KIF18A; KIF17; KIF16B; KIF5B; KIF5AA; KIF18B; KIF3B; KIF1B; KIF5A|
|microtubule binding||WDR81; MAP6; KIF5C; SPAG8; TRPV4; KIF5B; SNCA; KIF14; POLB; PAFAH1B1|
|motor activity||MYO7A; MYH15; DYNLRB1; MYO5A; MYH1E; KIF3C; MYHC4; VMHC; MYO10; MYL6B|
|protein binding||ZNF34; PKN2; ZBTB8A; CCR3; MAP1LC3B; MPHOSPH6; SGOL2; THY1; KRT80; FN1|
KIF5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF5A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF5A.
ANKRD27; RXRB; PCBD1; MDM2; Trak2; TRAK1; MAP4K4; TK1; Hap1; PIN1; TP53BP2; ITSN1; SMN1; TRAF3IP1; M