kif5b
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  • Official Full Name
  • kinesin family member 5B
  • Background
  • Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
  • Synonyms
  • KIF5B; kinesin family member 5B; KNS; KINH; KNS1; UKHC; HEL-S-61; kinesin-1 heavy chain; kinesin heavy chain; kinesin 1 (110-120kD); ubiquitous kinesin heavy chain; conventional kinesin heavy chain; epididymis secretory protein Li 61;
Cat.#:Kif5b-262RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Kif5b Protein, His-tagged
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Cat.#:KIF5B-377HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KIF5B, GST-tagged
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Cat.#:KIF5B-8648MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse KIF5B Protein
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Cat.#:KIF5B-3259RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KIF5B Protein
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Cat.#:Kif5b-326RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Kif5b protein, His-tagged
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Involved Pathway

KIF5B involved in several pathways and played different roles in them. We selected most pathways KIF5B participated on our site, such as Adaptive Immune System, Dopaminergic synapse, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF5B were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
IGLC2; FRS2B; SIGLEC8; KLHL21; FGF8B; HECTD3; CTLA4; CD300A; PIK3AP1; LAIR1
Dopaminergic synapse
ITPR1; DRD2; PPP2CA; KIF5C; GNAI1; ITPR3; PPP3CA; KCNJ5; GNB1; CREB5
Endocytosis
ARR3B; ARFGEF1; MVB12BB; CAPZA1B; WASH; VPS28; PRKCI; DNAJC6; FAM21A; CYTH4
Factors involved in megakaryocyte development and platelet production
KIF5B; IRF2A; KIF4; HBB-Y; AKAP1B; HBG2; MAFGA; ZFPM2A; LRRC16A; OSTN
Hemostasis
HBBE2; SLC3A2B; RHOB; GRB7; SERPINB8; F13A1B; BRPF3; HBD; KIF15; CD9B
Immune System
KIF3C; NCR3LG1; KIF5A; LRSAM1; CFD; LILRB5; GRAP2A; TRIM9; ASB9; CD300LB
Insulin Signaling
MINK1; MAPK6; SGK2; MAP3K9; ARHGAP33; STXBP2; MAP4K1; GRB14; SNAP25A; STXBP4
Insulin processing
SLC30A8; EXOC8; KIF5B; PCSK2; SLC30A5; CPN1; EXOC6; EXOC1; EXOC5; EXOC3

Protein Function

KIF5B has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF5B itself. We selected most functions KIF5B had, and list some proteins which have the same functions with KIF5B. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein BCKDK; FASTK; SGK3; HELZ2; SHPRH; ADCY7; PHKG1; FAM20C; AKT1; DALRD3
Function ATP-dependent microtubule motor activity, plus-end-directed
Related Protein KIF5AA; KIF20B; KIF3A; KIF5C; KIF5A; KIF18A; KIF19; KIF17; KIF1B; KIF5B
Function microtubule binding
Related Protein SBDS; KATNAL1; KIF5AA; SGIP1; MAP6; GABARAPL1; RAB11A; TRAF3IP1; KIF7; DNM2
Function microtubule motor activity
Related Protein KIF12; KLC3; KIF22; KIF7; DYNLRB2; KLC1; KIF15; DNALI1; DNAH14; PROL1
Function protein binding
Related Protein AEBP2; MINK1; HTR6; C19orf46; ACP1; SLC26A6; HIST1H2BE; KCNK16; IGSF21B; JUN

Interacting Protein

KIF5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF5B here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF5B.
YWHAZ; YWHAQ; YWHAB; YWHAG; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; BCAR3; VDAC1; NME2; SFN; VHL; RANBP2; Hap1

KIF5B Related Articles

Hutarew, G; Hauser-Kronberger, C; et al. Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: evaluation of five different ALK antibody clones and ALK FISH. HISTOPATHOLOGY 65:398-407(2014).
Go, H; Jung, YJ; et al. Diagnostic method for the detection of KIF5B-RET transformation in lung adenocarcinoma. LUNG CANCER 82:44-50(2013).

KIF5B Related Gene Family

Kinesins (KIF)