KIF5B Protein, kinesin family member 5B


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Official Full Name kinesin family member 5B
Background Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
Synonyms KIF5B; kinesin family member 5B; KNS; KINH; KNS1; UKHC; HEL-S-61; kinesin-1 heavy chain; kinesin heavy chain; kinesin 1 (110-120kD); ubiquitous kinesin heavy chain; conventional kinesin heavy chain; epididymis secretory protein Li 61;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KIF5B-377H Recombinant Human KIF5B, GST-tagged E.coli GST
    Mouse KIF5B-8648M Recombinant Mouse KIF5B Protein Mammalian Cell His
    Rat Kif5b-262R Recombinant Rat Kif5b Protein, His-tagged E.coli His
    Rat KIF5B-3259R Recombinant Rat KIF5B Protein Mammalian Cell His
    Rat Kif5b-326R Recombinant Rat Kif5b protein, His-tagged E.coli His

    KIF5B involved in several pathways and played different roles in them. We selected most pathways KIF5B participated on our site, such as Adaptive Immune System, Dopaminergic synapse, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System LILRB5; KIF22; NRG2A; STUB1; CTSL1; CTSK; TRIM11; ERAP1; CTSB; RNF144B
    Dopaminergic synapse GNG4; CALM1; GSK3B; MAPK11; ITPR1; PPP3CC; CALY; GNAQ; KCNJ5; PPP2R2A
    Endocytosis TFR1A; WIPF2; ZFP652; GIT2; CLTCA; SMURF2; RNF41; HSPA1A; CDC42; VPS37C
    Factors involved in megakaryocyte development and platelet production OSTN; CENPE; AKAP1; IRF1B; DOCK11; VPS45; MAFGB; GATA2A; HBG1; KIF20A
    Immune System CD226; ERAP1; TRIM56; UFL1; DEFB103A; PANX1; ASB17; HECTD3; TCIRG1; HUWE1
    Insulin Signaling MAP3K2; MAPK6; MAPK4; SGK2; INPP4AA; ARHGAP33; FLOT1; MAP3K10; STXBP2; STXBP3A
    Insulin processing SLC30A8; CPN1; EXOC6; PCSK1; RAB27A; KIF5B; PCSK2; SLC30A6; SLC30A5; EXOC8

    KIF5B has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF5B itself. We selected most functions KIF5B had, and list some proteins which have the same functions with KIF5B. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding KIF5C; STK24B; TAOK2; MYO5C; MAP2K7; TWF2; TAE1; HELLS; TNK2; MYO5B
    ATP-dependent microtubule motor activity, plus-end-directed KIF5A; KIF14; KIF17; KIF3B; KIF16B; KIF19; KIF5C; KIF5B; KIF1B; KIF5AA
    microtubule binding MAP1LC3C; GAS2L2; WDR81; CDK5RAP2; CASC1; MID2; KIF2A; KIF9; KIF19; CCDC88A
    microtubule motor activity DNAIC2; KIF3CB; DNALI1; DYNC2H1; KIF21A; KIF15; KIF27; KIF20A; DNAH14; KIF12
    protein binding CSF2RA; LETMD1; ARHGEF6; PACS1; RPGRIP1L; IL10RA; MBIP; EEA1; PCK2; IL5RA

    KIF5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF5B here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF5B.

    YWHAZ; YWHAQ; YWHAB; YWHAG; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; BCAR3; VDAC1; NME2; SFN; VHL; RANBP2; Hap1

    Hutarew, G; Hauser-Kronberger, C; et al. Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: evaluation of five different ALK antibody clones and ALK FISH. HISTOPATHOLOGY 65:398-407(2014).
    Go, H; Jung, YJ; et al. Diagnostic method for the detection of KIF5B-RET transformation in lung adenocarcinoma. LUNG CANCER 82:44-50(2013).

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