|Official Full Name||Kruppel-like factor 2 (lung)|
|Background||Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell;trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L;(SELL; MIM 153240) (summary by Weinreich et al., 2009 (PubMed 19592277)).|
|Synonyms||KLF2; Kruppel-like factor 2 (lung); Krueppel-like factor 2; LKLF; KLF 2; KLF2_HUMAN; Kruppel like factor 2; Kruppel like factor; Kruppel like factor LKLF; Lung krueppel like factor; Lung krueppel-like factor; Lung Kruppel like zinc finger transcription factor; Kruppel-like factor LKLF; lung Kruppel-like zinc finger transcription factor|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KLF2 involved in several pathways and played different roles in them. We selected most pathways KLF2 participated on our site, such as FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|FoxO signaling pathway||PDPK1B; MAPK12B; GRM1; BCL6A; SMAD3; PRKAG2A; FOXO1B; PIK3R2; HRAS; HOMER3|
KLF2 has several biochemical functions, for example, metal ion binding, protein binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLF2 itself. We selected most functions KLF2 had, and list some proteins which have the same functions with KLF2. You can find most of the proteins on our site.
|metal ion binding||PON3; TGM4; ZNF865; ZNF256; NEK3; HBAE1; CYP2K16; KLF2; VPS29; BCL11A|
|protein binding||IKBKE; HTATIP2; OTUB2; ALDH7A1; PSMB4; TPM1; ZBTB17; FGF1; GTF2B; SETMAR|
|sequence-specific DNA binding||KLF2; NKX2.4A; ISL1L; LHX2B; HOXA3A; FOXA3; HOXA13A; ATF4B1; Trl; NFE2L2B|
|transcription factor activity, sequence-specific DNA binding||RARAA; GLI4; SPIB; MAX; GLI3; HIST1H2AH; IRF1B; E2F1; HIVEP2A; RARAB|
KLF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLF2.