lin37
Share
  • Official Full Name
  • lin-37 homolog (C. elegans)
  • Background
  • This gene encodes a protein expressed in the eye.
  • Synonyms
  • LIN37; lin-37 homolog (C. elegans); protein lin-37 homolog; F25965; lin 37; ZK418.4; MGC9505; OTTMUSP00000032215; OTTMUSP00000032216; 1810054G18Rik; Antolefinin; Antolefinine; Lin 37 homolog (C. elegans); LIN37_HUMAN; OTTMUSP00000032214; Protein F25965; Protein lin 37 homolog; RGD1308901; lin-37
Cat.#:LIN37-1608HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human LIN37
+Inquiry
Cat.#:LIN37-9114MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LIN37 Protein
+Inquiry
Cat.#:LIN37-2609ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish LIN37
+Inquiry
Cat.#:LIN37-4732HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human LIN37 293 Cell Lysate
+Inquiry

Involved Pathway

LIN37 involved in several pathways and played different roles in them. We selected most pathways LIN37 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, G0 and Early G1, which may be useful for your reference. Also, other proteins which involved in the same pathway with LIN37 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
SGOL1; HTATIP; CKS1B; MAPRE1A; NUF2; WRAP53; GADD45BA; ACTR1A; PTTG1; SMARCA5
Cell Cycle, Mitotic
SGOL2; PDS5A; TUBGCP4; NEDD1; VRK1; NCAPG; CDCA8; KIF2A; NDC80; LIN52
G0 and Early G1
TOP2A; PIANP; LIN52; LIN37; LIN54; LIN9; DYRK1A; E2F4; MYBL2
G2/M Transition
NUMA1; SDCCAG8; TCTN2; ODF2B; NDE1; DCTN2; TUBGCP5; DCTN1A; TUBG1; TSGA14
Mitotic G1-G1/S phases
LIN37; LIN9; TOP2A; LIN54; MYCA; MYBL2; DYRK1A; LIN52
Mitotic G2-G2/M phases
BORA; TUBGCP2; CDK11B; CDK11A; TUBGCP3; FOXM1; NUMA1; TUBGCP4; LIN52; TCTN2
Polo-like kinase mediated events
LIN52; LIN37; FOXM1; LIN9

Protein Function

LIN37 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LIN37 itself. We selected most functions LIN37 had, and list some proteins which have the same functions with LIN37. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein UBE2D2A; SMOC1; PIANP; TMCO6; TAGLN; STK38L; TCF7; SEC22C; CDH1; LIG4

Interacting Protein

LIN37 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIN37 here. Most of them are supplied by our site. Hope this information will be useful for your research of LIN37.
RBL2; MAGEA6; CDR2; KRT31

LIN37 Related Articles

Sandoval, R; Pilkinton, M; et al. Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex. EXPERIMENTAL CELL RESEARCH 315:2914-2920(2009).
Litovchick, L; Sadasivam, S; et al. Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. MOLECULAR CELL 26:539-551(2007).