LNPEP

  • Official Full Name

    leucyl/cystinyl aminopeptidase

  • Overview

    IRAP (also known as LNPEP) was originally described as an insulin-responsive aminopeptidase found in Glut4-containing vesicles. It is essentially always in the same compartments as Glut4 and has identical insulin-stimulated translocation patterns as Glut4 Aminopeptidase, Bacterial leucyl aminopeptidase, EC 3.4.11.10; Aeromonas proteolytica aminopeptidase; EC 3.4.11.1; EC 3.4.11.5; LAP; LAPEP; PEPS; Leucine aminopeptidase; Leucyl aminopeptidase; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase; leucine aminopeptidase 3; leucyl aminopeptidase; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I.

  • Synonyms

    LNPEP;leucyl/cystinyl aminopeptidase;leucyl-cystinyl aminopeptidase;CAP;cystinyl aminopeptidase;P LAP;placental leucine aminopeptidase;PLAP;otase;oxytocinase;vasopressinase;AT (4) receptor;angiotensin IV receptor;insulin-regulated aminopeptid;Aeromonas Aminopeptidase;Aminopeptidase protein;Aminopeptidase;Bacterial leucyl aminopeptidase;EC 3.4.11.10;Aeromonas proteolytica aminopeptidase;EC 3.4.11.1;EC 3.4.11.5;LAP;LAPEP;PEPS;Leucine aminopeptidase;Leucyl aminopeptidase;Peptidase S;Proline aminopeptidase;Prolyl aminopeptidase;leucine aminopeptidase 3;leucyl peptidase;cytosol aminopeptidase;cathepsin III;L-leucine aminopeptidase;leucinaminopeptidase;leucinamide aminopeptidase;FTBL proteins;proteinates FTBL;aminopeptidase II;aminopeptidase III;aminopeptidase I

Recombinant Proteins

  • Human
  • Aeromonas
  • Zebrafish
  • Rat
  • Mouse
  • HEK293
  • Aeromonas Proteolytica
  • Mammalian Cells
  • E.coli
  • DDK
  • Myc
  • Non
  • His
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
LNPEP-29H Recombinant Human LNPEP protein, MYC/DDK-tagged HEK293 Human DDK&Myc
Aminopeptidase-86A Recombinant Aeromonas Aminopeptidase Aeromonas Proteolytica Aeromonas Non
LNPEP-10022Z Recombinant Zebrafish LNPEP Mammalian Cells Zebrafish His
LNPEP-3430R Recombinant Rat LNPEP Protein Mammalian Cells Rat His
LNPEP-9167M Recombinant Mouse LNPEP Protein Mammalian Cells Mouse His
LNPEP-4705HCL Recombinant Human LNPEP 293 Cell Lysate HEK293 Human Non
Kit-1079 Aminopeptidase N (APN/CD13) Activity Assay Kit (Fluorometric) Non
LNPEP-12H Recombinant Human LNPEP Protein, His-tagged E.coli Human His Leu782~Leu1025
LNPEP-1309H Recombinant Human LNPEP Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
LNPEP-1309H-B Recombinant Human LNPEP Protein Pre-coupled Magnetic Beads HEK293 Human
LNPEP-3086R Recombinant Rat LNPEP Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
LNPEP-3086R-B Recombinant Rat LNPEP Protein Pre-coupled Magnetic Beads HEK293 Rat
LNPEP-3469H Recombinant Human LNPEP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Lnpep-3805M Recombinant Mouse Lnpep Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
LNPEP-5123M Recombinant Mouse LNPEP Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
LNPEP-5123M-B Recombinant Mouse LNPEP Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    LNPEP involved in several pathways and played different roles in them. We selected most pathways LNPEP participated on our site, such as Renin-angiotensin system, which may be useful for your reference. Also, other proteins which involved in the same pathway with LNPEP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Renin-angiotensin system KLK1,KLK1B1,ENPEP,ACE2,MRGPRD,KLK1B3,AGTR1A,KLK1B9,MAS1,ACE

    Protein Function

    LNPEP has several biochemical functions, for example, aminopeptidase activity,metalloaminopeptidase activity,metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LNPEP itself. We selected most functions LNPEP had, and list some proteins which have the same functions with LNPEP. You can find most of the proteins on our site.

    Function Related Protein
    metalloaminopeptidase activity ANPEPB,LTA4H,RNPEPL1,TRHDE,RNPEP,ANPEPA,ENPEP,ERAP1,METAP2B,XPNPEP1
    protein binding PKN1,GRHL2,RCOR1,ZHX2,BANF1,U2AF1,USP18,CD4,ZBTB1,CLPX
    metallopeptidase activity ADAM15,STAMBPA,MMP23B,TAF2,MMP1A,ANPEPB,MEP1A.2,MMP14A,MMP2,GM5136
    zinc ion binding TRIM67,HE1B,TAF15,MMP13,RASSF1,CBL,TRIM8,ADAM10,ADAMTS15A,ZDHHC21
    aminopeptidase activity METAP1D,CTSL2,ERAP2,LTA4H,ENPEP,TPP2,TRHDE,CTSH,XPNPEP2,ERAP1
    peptide binding NPFFR1L3,IDE,RNPEP,H2-Q10,HCRTR2,AVPR2L,RPS6KB2,PPYR1,ANPEPB,ANPEP

    Interacting Protein

    LNPEP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LNPEP here. Most of them are supplied by our site. Hope this information will be useful for your research of LNPEP.

    TCF4;REL;FATE1;TNKS2;argS;b3xyc5_sollc;cona_canen;Junb;CANX;HEATR3;TMEM263;GCC1;DROSHA;NDUFA13

    Resources

    Research Area

    References

    • Haralambieva, IH; Oberg, AL; et al. High-Dimensional Gene Expression Profiling Studies in High and Low Responders to Primary Smallpox Vaccination. JOURNAL OF INFECTIOUS DISEASES 206:1512-1520(2012).

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