LNPEP Protein, leucyl/cystinyl aminopeptidase

LNPEP

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LNPEP

Official Full Name leucyl/cystinyl aminopeptidase
Background IRAP (also known as LNPEP) was originally described as an insulin-responsive aminopeptidase found in Glut4-containing vesicles. It is essentially always in the same compartments as Glut4 and has identical insulin-stimulated translocation patterns as Glut4 Aminopeptidase, Bacterial leucyl aminopeptidase, EC 3.4.11.10; Aeromonas proteolytica aminopeptidase; EC 3.4.11.1; EC 3.4.11.5; LAP; LAPEP; PEPS; Leucine aminopeptidase; Leucyl aminopeptidase; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase; leucine aminopeptidase 3; leucyl aminopeptidase; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I.
Synonyms LNPEP; leucyl/cystinyl aminopeptidase; leucyl-cystinyl aminopeptidase; CAP; cystinyl aminopeptidase; P LAP; placental leucine aminopeptidase; PLAP; otase; oxytocinase; vasopressinase; AT (4) receptor; angiotensin IV receptor; insulin-regulated aminopeptid; Aeromonas Aminopeptidase; Aminopeptidase protein; Aminopeptidase; Bacterial leucyl aminopeptidase; EC 3.4.11.10; Aeromonas proteolytica aminopeptidase; EC 3.4.11.1; EC 3.4.11.5; LAP; LAPEP; PEPS; Leucine aminopeptidase; Leucyl aminopeptidase; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase; leucine aminopeptidase 3; leucyl peptidase; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I
    • Type:
    • Species :
    • Aeromonas
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Aeromonas Proteolytica
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human LNPEP-29H Recombinant Human LNPEP protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human LNPEP-4705HCL Recombinant Human LNPEP 293 Cell Lysate HEK293 N/A
    Mouse LNPEP-9167M Recombinant Mouse LNPEP Protein Mammalian Cell His
    Rat LNPEP-3430R Recombinant Rat LNPEP Protein Mammalian Cell His
    Zebrafish LNPEP-10022Z Recombinant Zebrafish LNPEP Mammalian Cell His
    Aeromonas Aminopeptidase-86A Recombinant Aeromonas Aminopeptidase Aeromonas Proteolytica N/A

    LNPEP involved in several pathways and played different roles in them. We selected most pathways LNPEP participated on our site, such as Renin-angiotensin system, which may be useful for your reference. Also, other proteins which involved in the same pathway with LNPEP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Renin-angiotensin system KLK1B24; KLK1; LNPEP; ENPEP; NLN; AGTR1B; ATP6AP2; MRGPRD; CMA1; KLK1B8

    LNPEP has several biochemical functions, for example, aminopeptidase activity, metalloaminopeptidase activity, metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LNPEP itself. We selected most functions LNPEP had, and list some proteins which have the same functions with LNPEP. You can find most of the proteins on our site.

    Function Related Protein
    aminopeptidase activity LAP3; RNPEP; BLMH; Npepo; DNPEP; CTSH; CTSL2; LTA4H; METAP2A; NPEPPS
    metalloaminopeptidase activity METAP2A; ANPEPA; METAP2B; ENPEP; TRHDE; RNPEPL1; XPNPEP1; Npepo; LNPEP; RNPEP
    metallopeptidase activity ADAM20; ERAP2; MMP30; DNPEP; C6AST1; NAALADL1; PAPLNB; ADAM28; ACE; GM12824
    peptide binding LNPEP; CCKAR; BDKRB1; NPFFR2; ANPEP; OXTRL; ADNP; GPR37L1; OXTR; H2-Q10
    protein binding PHF16; GM5506; ZNF750; UBAC1; Raet1a; GADD45A; SUPT4H1; COLGALT2; UBXN2B; CHMP4B
    zinc ion binding ADAM8; SHARPIN; RNF26; RNF144B; MMP10; KDM4B; CA5A; KDM4A; APOBEC2B; TET2

    LNPEP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LNPEP here. Most of them are supplied by our site. Hope this information will be useful for your research of LNPEP.

    TCF4; REL; FATE1; TNKS2; argS; b3xyc5_sollc; cona_canen; Junb; CANX; HEATR3; TMEM263; GCC1; DROSHA; NDUFA13

    Haralambieva, IH; Oberg, AL; et al. High-Dimensional Gene Expression Profiling Studies in High and Low Responders to Primary Smallpox Vaccination. JOURNAL OF INFECTIOUS DISEASES 206:1512-1520(2012).

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