LTB
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Official Full Name
lymphotoxin beta (TNF superfamily, member 3)
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Overview
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. -
Synonyms
LTB; lymphotoxin beta (TNF superfamily, member 3); TNFC; lymphotoxin-beta; p33; TNFSF3; LT beta; lymphotoxin beta; tumor necrosis factor C; TNF-C; LT-beta; OTTHUMP00000029185; OTTHUMP00000215145; tumor necrosis factor ligand superfamily member 3;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chimpanzee
- Cynomolgus Monkey
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- Human Cell
- Insect Cell
- Mammalian Cell
- His
- His (Fc)
- Avi
- SUMO
- N
- Strep II
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | LTB-285H | Recombinant Human LTB, StrepII-tagged | Human Cell | Strep II | 49-244, 196 a.a. | |
Mouse | LTB-9344M | Recombinant Mouse LTB Protein | Mammalian Cell | His | ||
Mouse | Ltb-7122M | Recombinant Mouse Ltb protein, His-tagged | E.coli | His | Ile58~Met304 | |
Mouse | LTB-5235M | Recombinant Mouse LTB Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | LTB-5235M-B | Recombinant Mouse LTB Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | Ltb-1750R | Recombinant Rat Ltb Protein, His-tagged | E.coli | N-His | Ala155-Val305 | |
Chimpanzee | LTB-4588C | Recombinant Chimpanzee LTB protein, His-tagged | E.coli | His | 49-244aa | |
Chimpanzee | LTB-4589C | Recombinant Chimpanzee LTB protein, His-SUMO-tagged | E.coli | His-SUMO | 49-244aa | |
Cynomolgus Monkey | LTB-1190C | Recombinant Cynomolgus LTB Protein, His-tagged | Insect Cell | His | ||
Mus musculus (Mouse) | RFL11585MF | Recombinant Full Length Mouse Lymphotoxin-Beta(Ltb) Protein, His-Tagged | E.coli expression system | His | Full Length (1-306) | |
Rhesus Macaque | LTB-2590R | Recombinant Rhesus monkey LTB Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | LTB-2410R | Recombinant Rhesus Macaque LTB Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | LTB-2410R-B | Recombinant Rhesus Macaque LTB Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
- LTB Related Articles
- LTB Related Research Area
LTB involved in several pathways and played different roles in them. We selected most pathways LTB participated on our site, such as Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Rheumatoid arthritis, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cytokine-cytokine receptor interaction | ACKR3B;VEGFC;CCL20B;PLEKHO2;IL11;TNFRSF14;KITLGB;CXCL9;LTB |
NF-kappa B signaling pathway | GADD45B;LTA;CCL13;ATM;Bcl2a1b;TNFRSF11A;IKBKB;LY96;Ccl21c |
Rheumatoid arthritis | IL6;HLA-DMB;TNF;CCL3L3;IFNG;ATP6V1E2;Il23a; Il12b;ITGB2L;CXCL1 |
LTB has several biochemical functions, for example, cytokine activity, receptor binding, tumor necrosis factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LTB itself. We selected most functions LTB had, and list some proteins which have the same functions with LTB. You can find most of the proteins on our site.
Function | Related Protein |
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cytokine activity | IL36G;WNT1;TNFSF13;IL17F;CSF1B;TNFSF9;NODAL;TNFSF12;HMGB1A |
receptor binding | FZD8;FASLG;TNFSF18;HFE;DIAPH1;SMAGP;IAPP;ABL1;TIGIT |
tumor necrosis factor receptor binding | BRE;TNFSF13B;CASP8;LTB;FADD;TRADD;TNFSF13;TNFSF10L3;TNFSF8 |
LTB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTB here. Most of them are supplied by our site. Hope this information will be useful for your research of LTB.
TNFSF14; galK; q7ch26_yerpe; isdC; rapA
- Q&As
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