lyve1
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  • Official Full Name
  • lymphatic vessel endothelial hyaluronan receptor 1
  • Background
  • Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
  • Synonyms
  • LYVE1; lymphatic vessel endothelial hyaluronan receptor 1; Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik; lymphatic vessel endothelial hyaluronic acid receptor 1; extra cellular link domain-containing 1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial HA receptor-1; extracellular link domain-containing protein 1; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; HAR
Cat.#:LYVE1-48HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LYVE1, GST-tagged
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Cat.#:LYVE1-28659THTag:Fc
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LYVE1, Fc-tagged
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Cat.#:LYVE1-5070HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Lymphatic Vessel Endothelial Hyaluronan Receptor 1, His-tagge
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Cat.#:Lyve1-5071MTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Lymphatic Vessel Endothelial Hyaluronan Receptor 1
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Cat.#:Lyve1-7388MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Lyve1, Fc tagged
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Cat.#:LYVE1-4404CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LYVE1
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Cat.#:LYVE1-5072HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Lymphatic Vessel Endothelial Hyaluronan Receptor 1
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Cat.#:LYVE1-47HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human LYVE1, His-tagged
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Cat.#:LYVE1-156HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LYVE1
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Cat.#:LYVE1-906HTag:N/A
Source (Host):High-5 insect cellsSpecies:Human
Product nameRecombinant Human Lymphatic Vessel Endothelial Hyaluronan Receptor 1
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Cat.#:LYVE1-907HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Lymphatic Vessel Endothelial Hyaluronan Receptor 1, His-tagged
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Cat.#:Lyve1-87MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Lyve1, His-tagged
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Cat.#:LYVE1-1937HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human LYVE1 cell lysate
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Cat.#:LYVE1-1452MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse LYVE1 cell lysate
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Involved Pathway

LYVE1 involved in several pathways and played different roles in them. We selected most pathways LYVE1 participated on our site, such as Glycosaminoglycan metabolism, Hyaluronan metabolism, Hyaluronan uptake and degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LYVE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosaminoglycan metabolism
GPC1A; HS3ST6; SLC35B2; OMD; FMODA; B3GNT3; ST3GAL3A; GLB1L; GPC5A; MAPK1IP1L
Hyaluronan metabolism
HAS3; KIAA1199; LYVE1; CHP; HAS1; STAB2
Hyaluronan uptake and degradation
STAB2; LYVE1; CHP
Metabolism
DBH; PNP5B; PDK4; ADH8A; PDP2; MED15; ALDH9A1A.2; SLC5A4; Sult2a2; NUDT5
Metabolism of carbohydrates
GYG1B; DSEL; CHST14; SLC5A9; GCKR; NHLRC1; HPSE; HAS1; GLB1L; KIAA1199

Protein Function

LYVE1 has several biochemical functions, for example, hyaluronic acid binding, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LYVE1 itself. We selected most functions LYVE1 had, and list some proteins which have the same functions with LYVE1. You can find most of the proteins on our site.
Function
Related Protein
Function hyaluronic acid binding
Related Protein STAB2; C1QBP; VCAN; CD44; IMPG2; HYAL2; HAPLN2; LYVE1; HAPLN1A; HAPLN3
Function protein binding
Related Protein ZFP488; ARMC2; BAZ2B; PLDN; KRT1; TLE1; TDGF1; HNRNPR; TRIM15; FAM153C
Function receptor activity
Related Protein CLEC4E; AMFR; VMN1R44; ATRN; CD200R2; KLRG1; MED17; OGFRL1; PVRL3; GUCY1B3
Function transmembrane signaling receptor activity
Related Protein CD72; FZD8B; MRC1; OR4F29; NRXN3; FZD1; GIPR; CD300C; TLR5; DCC

Interacting Protein

LYVE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LYVE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LYVE1.
KRTAP10-8

LYVE1 Related Articles

Park, SM; Angel, CE; et al. Mapping the Distinctive Populations of Lymphatic Endothelial Cells in Different Zones of Human Lymph Nodes. PLOS ONE 9:-(2014).
Davis, JM; Hyjek, E; et al. Lymphatic Endothelial Differentiation in Pulmonary Lymphangioleiomyomatosis Cells. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 61:580-590(2013).