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MARK3

  • Official Full Name

    MAP/microtubule affinity-regulating kinase 3

  • Overview

    Microtubule associated proteins regulate the stability of microtubules and control processes such as cell polarity/differentiation, neurite outgrowth, cell division and organelle trafficking. The MARK (MAP/microtubule affinity-regulating kinases) family (
  • Synonyms

    MARK3; MAP/microtubule affinity-regulating kinase 3; CTAK1; KP78; EMK-2; C-TAK1; ELKL motif kinase 2; protein kinase STK10; ser/Thr protein kinase PAR-1; cdc25C-associated protein kinase 1; serine/threonine-protein kinase p78; PAR1A; Par-1a;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MARK3-5450H Recombinant Human MAP/Microtubule Affinity-Regulating Kinase 3, GST-His-tagged Sf9 Insect Cell GST/His
Human MARK3-26831TH Recombinant Human MARK3 N/A
Human MARK3-979H Recombinant Human MARK3, His & GST tagged Insect Cell His/GST
Human MARK3-349H Recombinant Human MARK3, GST-tagged, Active Sf9 Insect Cell GST
Human MARK3-733H Recombinant Human MARK3 Protein, His-tagged E.coli His
Human MARK3-582HCL Recombinant Human MARK3 cell lysate Insect Cell N/A
Human MARK3-4278H Recombinant Human MARK3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MARK3-548H Recombinant Human MARK3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human MARK3-7349HF Active Recombinant Full Length Human MARK3 Protein, GST-tagged Insect (sf21) GST 1-729
Mouse MARK3-9569M Recombinant Mouse MARK3 Protein Mammalian Cell His
Mouse Mark3-3961M Recombinant Mouse Mark3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse MARK3-5374M Recombinant Mouse MARK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MARK3-5374M-B Recombinant Mouse MARK3 Protein Pre-coupled Magnetic Beads HEK293
Rat MARK3-3590R Recombinant Rat MARK3 Protein Mammalian Cell His
Rat MARK3-3246R Recombinant Rat MARK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MARK3-3246R-B Recombinant Rat MARK3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MARK3-10257Z Recombinant Zebrafish MARK3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MARK3 Related Research Area

MARK3 involved in several pathways and played different roles in them. We selected most pathways MARK3 participated on our site, such as ARMS-mediated activation, Axon guidance, Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MARK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ARMS-mediated activationCRK;PTPRA;CSF2RB;KIDINS220B;PEA15;CNKSR1;NEFLB;RASGEF1A;FGF10B
Axon guidanceSRGAP3;NRAS;NCK2;NEFLB;PAK2;SPRED2;EPHA2;CDK5;RND1
Cytokine Signaling in Immune systemIRF6;CSK;PAQR3B;FRS2B;SPTBN2;SPNA2;OASL;NRG3;NRG2A
DAP12 interactionsCLEC5A;TREM1;HBEGF;SIGLEC15;ADRBK1;SIRPB1;PEA15;FRS2;RASGRP1
DAP12 signalingLCP2A;IL17RD;MARK3;FGFR1B;AGO2;PEA15A;FRS2B;FGF10B;CNKSR1
Developmental BiologyAP2B1;MYL12A;SPTBN1;HIF3A;CD24;SALL4;FGF8B;CEBPA;EFNA3B
Downstream signal transductionFGFR1B;SPTA1;DUSP10;DUSP2;FRS2B;DUSP9;THEM4;DAB2IPB;SPNA1
Downstream signaling of activated FGFR1MARK3;SPTA1;PEA15;DUSP9;KBTBD7;WDR83;PAQR3A;RASGEF1A;PAQR3B

MARK3 has several biochemical functions, for example, ATP binding, protein binding, protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MARK3 itself. We selected most functions MARK3 had, and list some proteins which have the same functions with MARK3. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMYHC4;STRADB;HSPA4L;PRKACG;MAPK12;DHX58;RET;RAD50;ERBB4A
protein bindingPPM1F;NOTCH4;GSTZ1;RNF4;SLC22A6;IRF7;PPP5C;EXOSC5;KCND2
protein serine/threonine kinase activityRIOK2;TSSK6;CDK1;TLK1B;NLK2;IRAK2;CLK2;MAPK12A;CLK3

MARK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARK3.

YWHAZ; YWHAB; YWHAG

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