|Official Full Name||mediator complex subunit 30|
|Background||The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010]|
|Synonyms||MED30; mediator complex subunit 30; MED30S; THRAP6; TRAP25; mediator of RNA polymerase II transcription subunit 30; TRAP/Mediator complex component TRAP25; thyroid hormone receptor associated protein 6; thyroid hormone receptor-associated protein 6; putative mediator of RNA polymerase II transcription subunit 30; thyroid hormone receptor-associated protein complex 25 kDa component;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
MED30 involved in several pathways and played different roles in them. We selected most pathways MED30 participated on our site, such as Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Thyroid hormone signaling pathway||ITGAV; ATP1B3; KAT2B; HDAC2; HRAS; MED4; WNT4; NOTCH2; DIO3; MED27|
MED30 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MED30 itself. We selected most functions MED30 had, and list some proteins which have the same functions with MED30. You can find most of the proteins on our site.
|RNA polymerase II transcription cofactor activity||MED7; CRSP7; MED19; MED24; MED26; MED21; MED10; MED13L; MED17; MED9|
|ligand-dependent nuclear receptor transcription coactivator activity||MED17; PUS1; LRP2BP; ZMIZ2; RBM14; KDM1A; ENY2; SMARCD3; TSG101; CCDC62|
|protein binding||EFCAB12; FAM110A; NSF; SGK1; BAHD1; ZNF433; SPG7; MIF; SEC24A; FGF3|
|receptor activity||LYVE1; RET; ADIPOR1B; CD200; VPREB1; GRIA4B; Pla2r1; ITGB1A; MED16; IL10RB|
|thyroid hormone receptor binding||OASL; MED13; NR0B2; NCOR1; NCOA3; TRIP6; MED17; MED16; TAF11; PRMT2|
|transcription cofactor activity||POU2AF1; MAX; NRG1; BTG1; LDB1B; PHF21A; ZNF212; MED30; TFB2M; SLC26A3|
|vitamin D receptor binding||TAF11; MED30; MED16; MED24; SNW1; RUNX2B; TAF7; MED4; RXRA; MED1|
MED30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED30 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED30.
MED10; KRTAP10-9; DOCK8; CDK19; MED19; CDK8; MED9; MED26; PTBP3