MED9
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Official Full Name
mediator complex subunit 9
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Overview
The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17. -
Synonyms
MED9; mediator complex subunit 9; mediator of RNA polymerase II transcription, subunit 9 homolog (S. cerevisiae); mediator of RNA polymerase II transcription subunit 9; FLJ10193; MED25; Mediator subunit 25; MGC138234; mediator of RNA polymerase II transcription, subunit 9 homolog;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
MED9 involved in several pathways and played different roles in them. We selected most pathways MED9 participated on our site, such as Developmental Biology, Fatty acid, triacylglycerol, and ketone body metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | MED9;KIF4;CEBPB;SPTB;DCC;EFNA1;FGF18B;FRS2A;FOXH1 |
| Fatty acid, triacylglycerol, and ketone body metabolism | MED16;AGT;TIAM2;MED29;CTGF;PLIN2;AGPAT6;ACOT11;MED15 |
| Metabolism | KIAA1199;ACOT9.1;CERS4A;PHOSPHO1;CYP3A7-CYP3AP1;AFMID;MED20;OAZ2;NUDT11 |
| Metabolism of lipids and lipoproteins | DHCR24;CYP8B2;MED25;CYP4B1;CETP;ARSJ;MED23;CPNE6;CERS4A |
| PPARA activates gene expression | G0S2;MED20;MED9;GLIPR1;MED21;MED26;CTGF;MED29;MED8 |
| Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | G0S2;MED16;MED19;ANKRD1;MED6;CDK19;GRHL1;MED23;MED7 |
| Transcriptional regulation of white adipocyte differentiation | MED29;EGR2;MED22;MED18;MED9;CDK19;NR2F2;MED19;EBF1 |
MED9 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MED9 itself. We selected most functions MED9 had, and list some proteins which have the same functions with MED9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription cofactor activity | MED26;MED14;MED31;MED13;MED12;MED10;NKX2;MED4;MED13L |
| protein binding | FAM167A;ZNF136;ZNF263;MAP3K3;PPARG;ANXA6;SH3GL3;EPN1;GTF3C3 |
MED9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED9 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED9.
MED4; CDK8; MED10; MED21
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