med9
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  • Official Full Name
  • mediator complex subunit 9
  • Background
  • The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
  • Synonyms
  • MED9; mediator complex subunit 9; mediator of RNA polymerase II transcription, subunit 9 homolog (S. cerevisiae); mediator of RNA polymerase II transcription subunit 9; FLJ10193; MED25; Mediator subunit 25; MGC138234; mediator of RNA polymerase II transcription, subunit 9 homolog
Cat.#:MED9-4463HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MED9 Protein, GST-tagged
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Cat.#:MED9-9708MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MED9 Protein
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Cat.#:MED9-2728RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MED9 Protein, His-tagged
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Cat.#:MED9-5016CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MED9
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Cat.#:MED9-4377HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MED9 293 Cell Lysate
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Involved Pathway

MED9 involved in several pathways and played different roles in them. We selected most pathways MED9 participated on our site, such as Developmental Biology, Fatty acid, triacylglycerol, and ketone body metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED9 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Developmental Biology
INSM1B; MED31; HIF3A; MYL12A; COL4A3; AP2M1; FGF8B; EPHA2A; CAP1; CFC1
Fatty acid, triacylglycerol, and ketone body metabolism
HELZ2; AGPAT6; MED23; MED22; PPARGC1B; ACSF3; MED16; APOA5; ACSF2; STIL
Metabolism
MED18; CEPT1; CETP; GLRX; ACMSD; MED25; CYP8B2; ADH8B; AWAT2; SGMS2
Metabolism of lipids and lipoproteins
CYP24A1; ALOX5AP; CYP2N13; CPNE3; FABP12; DHCR24; CYP2Y3; APOC2; MED8; LBR
PPARA activates gene expression
APOA5; MED22; G0S2; MED26; MED9; MED18; CDK19; MED15; MED16; ANKRD1
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
MED29; MED26; MED22; CTGF; MED19; CDK19; MED18; MED9; GLIPR1; MTF1
Transcriptional regulation of white adipocyte differentiation
EBF1; NR2F2; CDK19; MED22; EGR2; MED29; MED18; MED9; MED21; MED19

Protein Function

MED9 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MED9 itself. We selected most functions MED9 had, and list some proteins which have the same functions with MED9. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II transcription cofactor activity
Related Protein MED10; RBM14; MED19; MED7; MED21; MED22; NKX2; MED4; MED13L; TP53BP1
Function protein binding
Related Protein HACL1; COPS7A; ERCC5; GAPDHS; CRB3; PDZD7; NLGN4Y; EIF2S3; MDFIC; NAALADL2

Interacting Protein

MED9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED9 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED9.
MED4; CDK8; MED10; MED21