mis12
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  • Official Full Name
  • MIS12, MIND kinetochore complex component, homolog (S. pombe)
  • Background
  • Protein MIS12 homolog is a protein that in humans is encoded by the MIS12 gene.
  • Synonyms
  • MIS12; MIS12, MIND kinetochore complex component, homolog (S. pombe); MIS12, MIND kinetochore complex component, homolog (yeast); protein MIS12 homolog; hMIS12; KNTC2AP; MGC2488; MTW1; homolog of yeast Mis12; MIND kinetochore complex component, homolog (yeast); MIS12 homolog (yeast); MIS12 homolog; MIS12 MIND kinetochore complex component homolog (yeast); MTW 1; 2510025F08Rik
Cat.#:MIS12-5354HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MIS12 Protein, GST-tagged
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Cat.#:MIS12-7228HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MIS12, His-tagged
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Cat.#:MIS12-889HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MIS12, His-tagged
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Cat.#:MIS12-3691RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MIS12 Protein
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Cat.#:MIS12-2775RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MIS12 Protein, His-tagged
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Cat.#:MIS12-3469CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MIS12
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Cat.#:MIS12-4308HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MIS12 293 Cell Lysate
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Involved Pathway

MIS12 involved in several pathways and played different roles in them. We selected most pathways MIS12 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with MIS12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
CENPJ; SGOL2; WAPAL; KIF2A; TUBG1; HAUS2; CEP290; CDC7; TUBGCP4; YWHAQ
Cell Cycle, Mitotic
TUBGCP4; CENPN; KIF20A; PLK4; CDK6; CENPO; FGFR1OP; CENPL; NUMA1; CDKN2D
M Phase
RCC2; STAG1; SMC2; ZWINT; CENPL; ARPP19; CENPC1; SPC24; APITD1; NDEL1
Mitotic Anaphase
CDCA5; PANE1; INCENP; ZWILCH; NDEL1B; ITGB3BP; CENPI; VRK2; WAPAL; NSL1
Mitotic Metaphase and Anaphase
CENPK; ANKLE2; MLF1IP; ITGB3BP; CCDC99; PMF1; SKA1; ERCC6L; ZWILCH; CENPO
Mitotic Prometaphase
SGOL2; PANE1; NCAPD2; NSL1; AHCTF1; NDC80; SKA2; SPDL1; MIS12; CENPN
RHO GTPase Effectors
CDCA8; CLIP1; ERCC6L; TAX1BP3; ACTR2B; CCDC99; NF2A; SKA2; PMF1; RHOGA
RHO GTPases Activate Formins
ZW10; DSN1; CLIP1; ZWINT; RHOC; RCC2; FMNL1; ZWILCH; MKL1B; KNTC1

Protein Function

MIS12 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MIS12 itself. We selected most functions MIS12 had, and list some proteins which have the same functions with MIS12. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein AGAP2; FBL; SESN2; ZWINT; MFAP4; HPSE; IFT172; RND2; PDE9A; NEFM

Interacting Protein

MIS12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MIS12 here. Most of them are supplied by our site. Hope this information will be useful for your research of MIS12.
PMF1; ZWINT; NDC80; SPC24