|Official Full Name||melanocortin 2 receptor accessory protein|
|Background||This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described.|
|Synonyms||MRAP; melanocortin 2 receptor accessory protein; C21orf61, chromosome 21 open reading frame 61; melanocortin-2 receptor accessory protein; B27; FALP; fat tissue-specific low MW protein; fat cell-specific low molecular weight protein; FGD2; GCCD2; C21orf6|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
MRAP involved in several pathways and played different roles in them. We selected most pathways MRAP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MRAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
MRAP has several biochemical functions, for example, corticotropin hormone receptor binding, protein binding, type 1 melanocortin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRAP itself. We selected most functions MRAP had, and list some proteins which have the same functions with MRAP. You can find most of the proteins on our site.
|corticotropin hormone receptor binding||MRAP; MRAP2|
|protein binding||MATN1; VTN; MRPL40; HENMT1; ZNF511; S100A10; CEACAM6; RAC1; C1QTNF8; EIF3D|
|type 1 melanocortin receptor binding||MRAP; MRAP2; POMC; AGRP2|
|type 3 melanocortin receptor binding||ASIP; POMC; MRAP; MRAP2; a|
|type 4 melanocortin receptor binding||POMC; a; ASIP; MRAP; MRAP2|
|type 5 melanocortin receptor binding||MRAP; MRAP2|
MRAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRAP here. Most of them are supplied by our site. Hope this information will be useful for your research of MRAP.
MRAP2; MC4R; MC5R; MC3R; MC1R