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Official Full Name melanocortin 2 receptor accessory protein
Background This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described.
Synonyms MRAP; melanocortin 2 receptor accessory protein; C21orf61, chromosome 21 open reading frame 61; melanocortin-2 receptor accessory protein; B27; FALP; fat tissue-specific low MW protein; fat cell-specific low molecular weight protein; FGD2; GCCD2; C21orf6
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MRAP-1436H Recombinant Human MRAP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Mrap-4133M Recombinant Mouse Mrap Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human MRAP-1131HCL Recombinant Human MRAP cell lysate N/A
    Human MRAP-5530H Recombinant Human MRAP Protein, GST-tagged Wheat Germ GST
    Human MRAP-683H Recombinant Human MRAP Protein, Fc-tagged HEK293 Fc
    Mouse MRAP-10009M Recombinant Mouse MRAP Protein Mammalian Cell His

    MRAP involved in several pathways and played different roles in them. We selected most pathways MRAP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MRAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    MRAP has several biochemical functions, for example, corticotropin hormone receptor binding, protein binding, type 1 melanocortin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRAP itself. We selected most functions MRAP had, and list some proteins which have the same functions with MRAP. You can find most of the proteins on our site.

    Function Related Protein
    corticotropin hormone receptor binding MRAP; MRAP2
    protein binding MATN1; VTN; MRPL40; HENMT1; ZNF511; S100A10; CEACAM6; RAC1; C1QTNF8; EIF3D
    type 1 melanocortin receptor binding MRAP; MRAP2; POMC; AGRP2
    type 3 melanocortin receptor binding ASIP; POMC; MRAP; MRAP2; a
    type 4 melanocortin receptor binding POMC; a; ASIP; MRAP; MRAP2
    type 5 melanocortin receptor binding MRAP; MRAP2

    MRAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRAP here. Most of them are supplied by our site. Hope this information will be useful for your research of MRAP.

    MRAP2; MC4R; MC5R; MC3R; MC1R

    Johnson, SR; Swinton, JR; et al. Prognostic factors for survival in scleroderma associated pulmonary arterial hypertension. JOURNAL OF RHEUMATOLOGY 35:1584-1590(2008).
    Sebag, JA; Hinkle, PM; et al. Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104:20244-20249(2007).

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