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Official Full Name myotubularin related protein 2
Background This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.
Synonyms MTMR2; myotubularin related protein 2; CMT4B; myotubularin-related protein 2; KIAA1073; CMT4B1; MTMR2_HUMAN; OTTHUMP00000204445; OTTHUMP00000204446; OTTHUMP00000204447; OTTHUMP00000204448
    • Species :
    • Chicken
    • Human
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MTMR2-1090H Recombinant Human MTMR2, GST-tagged E.coli GST
    Human MTMR2-4074HCL Recombinant Human MTMR2 293 Cell Lysate HEK293 N/A
    Human MTMR2-4075HCL Recombinant Human MTMR2 293 Cell Lysate HEK293 N/A
    Human MTMR2-5718H Recombinant Human MTMR2 Protein, GST-tagged Wheat Germ GST
    Rhesus Macaque MTMR2-2902R Recombinant Rhesus monkey MTMR2 Protein, His-tagged Mammalian Cell His
    Chicken MTMR2-3338C Recombinant Chicken MTMR2 Mammalian Cell His
    Zebrafish MTMR2-8948Z Recombinant Zebrafish MTMR2 Mammalian Cell His

    MTMR2 involved in several pathways and played different roles in them. We selected most pathways MTMR2 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTMR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Inositol phosphate metabolism NUDT3A; NUDT4; PI4KA; PLCG1; MTMR7A; MINPP1; INPP5J; PIP5K1BA; PIP5K1AA; PIP5K2
    Metabolic pathways HYAL3; HPGDS; COX6A2; POLR2F; CYP2C8; PFKMA; COX5B; PPOX; HMGCLL1; PDXP
    Phosphatidylinositol signaling system PIK3C2B; PIP5K1BB; PTENA; PLCD1B; INPP5D; CALM2; IP6K1; CDS2; MTMR7B; PIP4K2B

    MTMR2 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by MTMR2 itself. We selected most functions MTMR2 had, and list some proteins which have the same functions with MTMR2. You can find most of the proteins on our site.

    Function Related Protein
    phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity MTMR1A; CTDSPL2A; PXYLP1; CTDSPL2B; MTMR8; MTMR1B; PTPRQ; MTM1; MTMR2; SACM1L
    phosphatidylinositol-3-phosphatase activity FIG4; MTMR14; MTMR2; PTEN; MTMR3; MTMR8; MTMR1B; SACM1L; MTMR1; MTM1
    protein binding DROSHA; CBL; TRIM63; HAGH; POLD4; SYVN1; ARFGAP3; HCST; CCR5; ZFYVE9
    protein homodimerization activity MIXL1; BNIP3; FGFR1OP; PVR; SRF; GTF2A2; SDS; GPD1; ZHX3; UNC13A
    protein tyrosine phosphatase activity DUSP4; PTPN13; PTPN23; DUPD1; PGP; DUSP12; PTPRG; PTP4A1; PTPRZ1; DNAJC6
    protein tyrosine/serine/threonine phosphatase activity DUSP3B; CDKN3; DUSP21; PTEN; PTPMT1; SSH2B; CTDSPL2A; SACM1L; MTMR2; SACM1LA

    MTMR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTMR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTMR2.

    NEFL; MTMR12; q7ard3_yerpe; tcaA1; metQ

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