myh7b
Share
  • Official Full Name
  • myosin, heavy chain 7B, cardiac muscle, beta
  • Background
  • Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of other eukaryotic motility processes. They are responsible for actin-based motility. The term was originally used to describe a group of similar ATPases found in striated and smooth muscle cells. Following the discovery by Pollard and Korn of enzymes with myosin-like function in Acanthamoeba castellanii, a large number of divergent myosin genes have been discovered throughout eukaryotes. Thus, although myosin was originally thought to be restricted to muscle cells (hence, "myo"), there is no single "myosin" but rather a huge superfamily of genes whose protein products share the basic properties of actin binding, ATP hydrolysis (ATPase enzyme activity), and force transduction. Virtually all eukaryotic cells contain myosin isoforms. Some isoforms have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. The structure and function of myosin is strongly conserved across species, to the extent that rabbit muscle myosin II will bind to actin from an amoeba.
  • Synonyms
  • MYH7B; myosin, heavy chain 7B, cardiac muscle, beta; SM2, SSMHC; myosin heavy chain; myosin, heavy polypeptide 7B, cardiac muscle, beta; myosin-7B; slow myosin 2
Cat.#:MYH7B-1481HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYH7B protein, His & GST-tagged
+Inquiry
Cat.#:MYH7B-960HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human MYH7B
+Inquiry
Cat.#:MYH7B-6156CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MYH7B
+Inquiry

Involved Pathway

MYH7B involved in several pathways and played different roles in them. We selected most pathways MYH7B participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYH7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Tight junction
ACTB; PRKCB; VMHC; RAB3B; ACTB2; CSNK2A2A; CASKA; KRAS; OCLNA; CLDN10

Protein Function

MYH7B has several biochemical functions, for example, ATP binding, actin binding, motor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYH7B itself. We selected most functions MYH7B had, and list some proteins which have the same functions with MYH7B. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PAK2A; MB21D1; KIF2B; ACTR2B; MYH8; AKT2L; UBA6; GUCY2E; TXK; ACSM5
Function actin binding
Related Protein LCP1; MYHC4; SPTAN1; INPPL1; ACTN4; CYFIP1; WASF1; DSTN; VCL; MKL1
Function motor activity
Related Protein SMYHC1; MYHZ1.1; DYNLL2; MYHC4; MYH9A; MYL6B; MYO5C; DCTN2; CGNB; KIF1C
Function protein binding
Related Protein RBPMS2B; RABGGTB; BACH1; KRT17; PARD6B; TDGF1; FSTL3; GHR; ACTA1; TRAF5

Interacting Protein

MYH7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYH7B here. Most of them are supplied by our site. Hope this information will be useful for your research of MYH7B.
SMYD1; TNS2; SRRM1; b4e0q1_human; KPNA4; PDCD6; FXR1; NCBP2; CACNA2D1; RBBP5; MRPS27; ESR2; PGAM5; SEC62; POLDIP3; POLDIP3; COPS7B; BCLAF1