MYO1C Protein, myosin IC


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Official Full Name myosin IC
Background This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.
Synonyms MYO1C; myosin IC; unconventional myosin-Ic; myr2; myosin-Ic; myosin I beta; myosin-I beta; nuclear myosin I; NMI; MMIb; MMI-beta; FLJ23903
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MYO1C-4009HCL Recombinant Human MYO1C 293 Cell Lysate HEK293 N/A
    Human MYO1C-5832H Recombinant Human MYO1C Protein, GST-tagged Wheat Germ GST
    Human MYO1C-8037H Recombinant Human MYO1C protein, His & GST-tagged E.coli His/GST
    Mouse MYO1C-10335M Recombinant Mouse MYO1C Protein Mammalian Cell His
    Rat MYO1C-3863R Recombinant Rat MYO1C Protein Mammalian Cell His
    Rat Myo1c-8038R Recombinant Rat Myo1c protein, His-tagged E.coli His
    Chicken MYO1C-1368C Recombinant Chicken MYO1C Mammalian Cell His

    MYO1C involved in several pathways and played different roles in them. We selected most pathways MYO1C participated on our site, such as Fcgamma receptor (FCGR) dependent phagocytosis, Immune System, Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYO1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fcgamma receptor (FCGR) dependent phagocytosis MYO9B; ABI1B; ABI2; ACTR2B; ACTR3; MYO1C; ACTR2; ARPC1A; PPAPDC1B; WIPF3
    Immune System DEFB121; UFL1; ISG20; BAIAP2; EGR1; TNIP2; GBP5; SAMHD1; ASB2; KPNA3
    Innate Immune System BTR30; MYO1C; BTR16; SUGT1; ABI1; CASP2; DUSP3; ACTR2B; DEFB106A; KIR2DS2
    Insulin Signaling SGK2; MYO1C; STXBP3; MAP3K9; INPP4AA; ARHGAP33; REG1A; MAPK4; RHOJ; STXBP2
    Membrane Trafficking CNIH3; CLVS1; CLVS2; SEC23IP; LMAN2L; CNO; SEC22A; TCEAL4; TRAPPC4; CLINT1
    Regulation of actin dynamics for phagocytic cup formation MYO1C; ABI1A; WIPF3; NCKIPSD; ABI1B; MYO9B; WIPF2
    Translocation of GLUT4 to the plasma membrane RAB10; RALAA; RALAB; STXBP3; MYO1C
    Vesicle-mediated transport TRAPPC10; GAK; HIP1RB; SEC23IP; PUM1; TRAPPC1; PICALM; MIA3; PLDN; MYO1C

    MYO1C has several biochemical functions, for example, ATP binding, Ral GTPase binding, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYO1C itself. We selected most functions MYO1C had, and list some proteins which have the same functions with MYO1C. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding RAD50; HYOU1; BMPR2; C10orf2; CASKA; MKI67; MVDA; CDK5; FLT4; ALPK1
    Ral GTPase binding RAB34; EXOC5; FLNA; EXOC4; LSM2; RNF41; PIH1D2; RALBP1; USP33; PRKCH
    actin binding MYLK; TWF1A; PARVA; FSCN1A; LIMCH1A; MYO6; NF2B; SPTAN1; CYFIP1; EPB41L3B
    actin-dependent ATPase activity MYO3A; MYO1C; MYH7; MYH10; MYL6; MYH9; MYO7A; MYO1D
    calmodulin binding SPA17; ITPKB; MYH7; TRPV1; MAPKAPK2; CAMK2G; MYO7A; MYH3; SPHK1; ATP2B1
    motor activity MYO1F; MYO1C; MYO10; MYO5C; KIF18B; MYO1E; DYNLRB1; MYO1A; MYO1EB; MYH15
    protein C-terminus binding PEX26; TOP2B; CDC20; ITGB3BP; ERCC3; SIRT1; SIAH1A; SHANK1; PEX1; CALCOCO1
    protein binding KCNIP2; NR2C2; DUSP2; PPP1R15B; RTN4RL2B; AGO2; FLVCR1; HDAC10; GAB1; IFNAR2
    receptor binding PVRL4; LAMA2; CD200; RSPO3; HAMP; SMARCD3; TNFSF18; ENSA; C3; NPPB

    MYO1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYO1C here. Most of them are supplied by our site. Hope this information will be useful for your research of MYO1C.

    ESR1; ESR2; GIPC1; PTP4A3; CIAO1; EIF4A2; MAP3K3; NEK6; WRAP73; USP20; RIPK3; PHLDA3; IKBKG; POLR1E; PLEKHG3; RIOK3; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

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