Recombinant Human MYO1C Protein, GST-tagged

• Cat.No.: MYO1C-5832H
• Product Overview: Human MYO1C full-length ORF ( NP_203693.2, 1 a.a. - 1028 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 144.3 kDa
• AA Sequence: MESALTARDRVGVQDFVLLENFTSE AAFIENLRRRFRENLIYTYIGPVLV SVNPYRDLQIYSRQHMERYRGVSFY EVPPHLFAVADTVYRALRTERRDQA VMISGESGAGKTEATKRLLQFYAET CPAPERGGAVRDRLLQSNPVLEAFG NAKTLRNDNSSRFGKYMDVQFDFKG APVGGHILSYLLEKSRVVHQNHGER NFHIFYQLLEGGEEETLRRLGLERN PQSYLYLVKGQCAKVSSINDKSDWK VVRKALTVIDFTEDEVEDLLSIVAS VLHLGNIHFAANEESNAQVTTENQL KYLTRLLSVEGSTLREALTHRKIIA KGEELLSPLNLEQAAYARDALAKAV YSRTFTWLVGKINRSLASKDVESPS WRSTTVLGLLDIYGFEVFQHNSFEQ FCINYCNEKLQQLFIELTLKSEQEE YEAEGIAWEPVQYFNNKIICDLVEE KFKGIISILDEECLRPGEATDLTFL EKLEDTVKHHPHFLTHKLADQRTRK SLGRGEFRLLHYAGEVTYSVTGFLD KNNDLLFRNLKETMCSSKNPIMSQC FDRSELSDKKRPETVATQFKMSLLQ LVEILQSKEPAYVRCIKPNDAKQPG RFDEVLIRHQVKYLGLLENLRVRRA GFAYRRKYEAFLQRYKSLCPETWPT WAGRPQDGVAVLVRHLGYKPEEYKM GRTKIFIRFPKTLFATEDALEVRRQ SLATKIQAAWRGFHWRQKFLRVKRS AICIQSWWRGTLGRRKAAKRKWAAQ TIRRLIRGFILRHAPRCPENAFFLD HVRTSFLLNLRRQLPRNVLDTSWPT PPPALREASELLRELCIKNMVWKYC RSISPEWKQQLQQKAVASEIFKGKK DNYPQSVPRLFISTRLGTDEISPRV LQALGSEPIQYAVPVVKYDRKGYKP RSRQLLLTPNAVVIVEDAKVKQRID YANLTGISVSSLSDSLFVLHVQRAD NKQKGDVVLQSDHVIETLTKTALSA NRVNSININQGSITFAGGPGRDGTI DFTPGSELLITKAKNGHLAVVAPRL NSR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MYO1C myosin IC [ Homo sapiens ]
• Official Symbol: MYO1C
• Synonyms: MYO1C; myosin IC; unconventional myosin-Ic; myr2; myosin-Ic; myosin I beta; myosin-I beta; nuclear myosin I; NMI; MMIb; MMI-beta; FLJ23903
• Gene ID: 4641
• mRNA Refseq: NM_001080779
• Protein Refseq: NP_001074248
• MIM: 606538
• UniProt ID: O00159