ndn
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  • Official Full Name
  • Ndn necdin
  • Background
  • This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed;exclusively from the paternal allele. Studies in mouse suggest that the protein encoded by this gene may suppress;growth in postmitotic neurons.
  • Synonyms
  • NDN; necdin; Peg6; AI528698;
Cat.#:NDN-30373THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human NDN
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Cat.#:NDN-10498MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NDN Protein
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Cat.#:NDN-2966RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NDN Protein, His-tagged
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Cat.#:NDN-3934HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human NDN 293 Cell Lysate
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Involved Pathway

NDN involved in several pathways and played different roles in them. We selected most pathways NDN participated on our site, such as Adipogenesis, p75(NTR)-mediated signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adipogenesis
CISD1; EGR2B; GADD45A; HMGA1; FRZB; CDKN1A; PLIN2; EBF1; AGPAT2; HMGA1-RS1
p75(NTR)-mediated signaling
PRDM4; BEX1; NDN; RTN4R; OMG; MAGEH1; RTN4; ZNF274

Protein Function

NDN has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, gamma-tubulin binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NDN itself. We selected most functions NDN had, and list some proteins which have the same functions with NDN. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein PATZ1; TBX15; SREBF2; TCF3; FOXD1; RBPJB; HELT; ZFP639; PAX5; NFIA
Function gamma-tubulin binding
Related Protein WASH; CEP57L1; TUBGCP5; BLOC1S2A; PIFO; NME2; DIXDC1; FEZ1; RACGAP1; BLOC1S2
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein GLI2; BCL11B; YBX1; PATZ1; HNF4A; TBX20; NFIA; MEF2B; PPARA; CEBPG

Interacting Protein

NDN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDN here. Most of them are supplied by our site. Hope this information will be useful for your research of NDN.
NCL; TMEM33; SEC61A1; RPS11; TRIM28; GOLGA4; EID3; EID2; EID2B; CERS2; NSMCE4A; MPP6; DHCR7; SRPRB; AUP1; EID1; EGFR; ARSE