Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

NEIL3

  • Official Full Name

    nei endonuclease VIII-like 3 (E. coli)

  • Overview

    NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate;the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA;strand break via the associated lyase reaction (Bandaru et al., 2002 (PubMed 12509226)).
  • Synonyms

    NEIL3; nei endonuclease VIII-like 3 (E. coli); endonuclease 8-like 3; FLJ10858; FPG2; hFPG2; hNEI3; 123; AI449477; BC034753; C85903; DNA glycosylase FPG2; DNA glycosylase hFPG2; DNA glycosylase/AP lyase Neil3; EC 3.2.2.-; EC 4.2.99.18; Endonuclease VIII-like 3; FGP2; MGC27861; MGC36916; nei endonuclease VIII-like 3; Nei like 3 (E. coli); Nei-like protein 3; NEIL3_HUMAN; OTTHUMP00000218810; RGD1310562; NEI3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NEIL3-912H Recombinant Human NEIL3 Mammalian Cell His
Human NEIL3-3880HCL Recombinant Human NEIL3 293 Cell Lysate HEK293 N/A
Human NEIL3-3609H Recombinant Human NEIL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NEIL3-3609H-B Recombinant Human NEIL3 Protein Pre-coupled Magnetic Beads HEK293
Mouse NEIL3-10568M Recombinant Mouse NEIL3 Protein Mammalian Cell His
Mouse NEIL3-6006M Recombinant Mouse NEIL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NEIL3-6006M-B Recombinant Mouse NEIL3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Neil3-1446M Recombinant Mouse Neil3 protein, His & T7-tagged E.coli His/T7 Val2~Val187 (Accession # Q8K203)
Zebrafish NEIL3-1724Z Recombinant Zebrafish NEIL3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NEIL3 involved in several pathways and played different roles in them. We selected most pathways NEIL3 participated on our site, such as Base excision repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEIL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Base excision repairmutY;LIG3;POLE3;PCNA;PNKP;SMUG1;TDG;NEIL3;NEIL2

NEIL3 has several biochemical functions, for example, DNA N-glycosylase activity, DNA-(apurinic or apyrimidinic site) lyase activity, bubble DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEIL3 itself. We selected most functions NEIL3 had, and list some proteins which have the same functions with NEIL3. You can find most of the proteins on our site.

Function Related Protein
DNA N-glycosylase activityOGG1;SMUG1;NTHL1;TDG;NEIL1;NEIL3
DNA-(apurinic or apyrimidinic site) lyase activityHMGA1-RS1;ALKBH1;APEX1;APLF;HMGA1B;NEIL1;NEIL3;NTHL1;HMGA2
bubble DNA bindingHMGB1;RECQL4;BLM;NEIL3;ERCC5;WRN
damaged DNA bindingMGMT;EP300;NEIL1;RAD23A;TP63;TP73;RBBP8;ERCC3;TRP63
double-stranded DNA bindingMCM10;RAD51AP1;HMGB3;HES2;HMGB2;DDX58;TEF;TP53;TP73
single-stranded DNA bindingSSBP4;CDAN1;NEIL3;TSN;RAD51AP1;POLR2GL;OBFC1;HMGB1;NCL
zinc ion bindingPEG10;CRIP2;MAP3K7IP3;IDE;PTPN1;ESR1;MUL1A;ANPEPB;DTX3

NEIL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEIL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEIL3.

TP53; TWIST1; SF3B2; PRPF40A; SLC2A1; RBM25; SMARCA4; Ect2; SFSWAP; NNT; ROCK1; GPATCH4; RSBN1L; BCL7C; HMCES; ENY2; CDKN2AIP; GLTSCR1; SLC25A13

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All NEIL3 Products

Required fields are marked with *

My Review for All NEIL3 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends