|Official Full Name||NIMA (never in mitosis gene a)- related kinase 9|
|Background||Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.|
|Synonyms||NEK9; NIMA (never in mitosis gene a)- related kinase 9; serine/threonine-protein kinase Nek9; DKFZp434D0935; MGC16714; Nek8; NERCC; nercc1 kinase; nimA-related kinase 8; NIMA-related kinase Nek8; nimA-related protein kinase 9; never in mitosis A-related k|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
NEK9 involved in several pathways and played different roles in them. We selected most pathways NEK9 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEK9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Activation of NIMA Kinases NEK9, NEK6, NEK7||NEK9; NEK6; NEK7|
|Cell Cycle||TMPO; MCM7; CDC14B; MPEG1.1; NEK2; GMNN; KNTC1; CHEK1; TERF1; MCM3L|
|Cell Cycle, Mitotic||NCAPH; CENPL; CENPI; CDK7; BANF1; DNA2; E2F4; TUBGCP3; MAU2; KIF2A|
|M Phase||GORASP1; KIF2B; NCAPG2; VRK2; ENSAA; ERCC6L; KIF2A; MLF1IP; MAU2; CTDNEP1A|
|Mitotic Prophase||SETB; ENSAB; SMC4; ARPP19A; ARPP19; MASTL; TMEM188; GORASP2; SETA; VRK2|
|Nuclear Envelope Breakdown||CNEP1R1; TMEM188; NEK7; CTDNEP1; NEK6; CTDNEP1B; NEK9; DULLARD; CTDNEP1A|
|Nuclear Pore Complex (NPC) Disassembly||NEK7; NEK9; NEK6|
NEK9 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by NEK9 itself. We selected most functions NEK9 had, and list some proteins which have the same functions with NEK9. You can find most of the proteins on our site.
|ATP binding||SETX; ASCC3; HK2; PFKFB1; ABCD3A; TTN; ADCK1; NEK7; GC2; FAM120B|
|metal ion binding||MAP3K3; SMAP2; PLAGX; REST; NEK8; MUT; KCNIP1B; OSR2; MUL1A; PDE11A|
|protein binding||SARM1; ABCG8; GFOD1; MRPS23; CYP2S1; G6PD; TMEM67; ANXA9; FKBP4; TSPAN6|
|protein kinase binding||JTB; SNAP91; AXIN2; CDC25A; NSF; CDK5; PFKFB2; CHEK2; IL12RB2; PIH1D1|
|protein serine/threonine kinase activity||PIK3CG; STK38L; STK36; CSNK1A1; VRK1; CLK2; TP53RK; GM711; TTK; PRKCI|
NEK9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEK9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEK9.
GABARAPL2; DYNLL1; PLK1; GABARAPL1