nek9
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  • Official Full Name
  • NIMA (never in mitosis gene a)- related kinase 9
  • Background
  • Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
  • Synonyms
  • NEK9; NIMA (never in mitosis gene a)- related kinase 9; serine/threonine-protein kinase Nek9; DKFZp434D0935; MGC16714; Nek8; NERCC; nercc1 kinase; nimA-related kinase 8; NIMA-related kinase Nek8; nimA-related protein kinase 9; never in mitosis A-related k
Cat.#:NEK9-1064Tag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human NEK9 protein, GST-tagged
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Cat.#:NEK9-1064HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human NEK9, GST-tagged
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Cat.#:NEK9-1259HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NEK9, GST-tagged
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Cat.#:NEK9-66HTag:Flag
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human NEK9 protein, Flag-tagged, Biotinylated
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Cat.#:NEK9-3000RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NEK9 Protein, His-tagged
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Cat.#:NEK9-3876HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NEK9 293 Cell Lysate
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Involved Pathway

NEK9 involved in several pathways and played different roles in them. We selected most pathways NEK9 participated on our site, such as Activation of NIMA Kinases NEK9, NEK6, NEK7, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEK9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of NIMA Kinases NEK9, NEK6, NEK7
NEK9; NEK7; NEK6
Cell Cycle
USO1; RBL1; ANAPC7; POT1; RB1; MAD2L2; CTDNEP1B; PCM1; RCC2; GMNN
Cell Cycle, Mitotic
ANKLE2; PDS5A; SKA1; BORA; CEP164; SPC24; CDKN1B; DPF1; B9D2; NEDD1
M Phase
NCAPH; CENPO; CENPE; APITD1; KIF2B; NCAPD3; NEK7; ARPP19A; GORASP2; NUF2
Mitotic Prophase
VRK1; NEK6; ENSAB; NCAPD3; SMC2; ARPP19B; ENSA; CTDNEP1B; SMC4; SET
Nuclear Envelope Breakdown
DULLARD; CTDNEP1; NEK9; CTDNEP1B; CNEP1R1; TMEM188; NEK6; NEK7; CTDNEP1A
Nuclear Pore Complex (NPC) Disassembly
NEK6; NEK9; NEK7

Protein Function

NEK9 has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEK9 itself. We selected most functions NEK9 had, and list some proteins which have the same functions with NEK9. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CLK2; ATP8B3; DHX58; HLCS; CAMK1DB; CKMT1B; ACTA2; DMC1; TOR1A; HSPA12A
Function metal ion binding
Related Protein AOX3; LHX6; NRXN2; PLCH2; NAIP1; Acsm2a; CLEC4M; RBM4B; PLEKHF1; BHLHE22
Function protein binding
Related Protein CREBZF; TAS2R16; SLIRP; LCMT1; COLQ; RSAD2; ALDH1A2; SRMS; GNAQ; MPZL2
Function protein kinase binding
Related Protein CNTLN; IL31RA; PPP1R12B; NCS1; CACNB3; CDH2; FAM83E; PPP1R12A; CDKN2C; NPR1
Function protein serine/threonine kinase activity
Related Protein VRK2; TLK2; SMOK3A; SGK3; BMPR2B; DCLK1A; IRAK3; PRKCA; SRPK3; WNK1

Interacting Protein

NEK9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEK9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEK9.
GABARAPL2; DYNLL1; PLK1; GABARAPL1