nudt21
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  • Official Full Name
  • nudix (nucleoside diphosphate linked moiety X)-type motif 21
  • Background
  • The protein encoded by this gene is one subunit of a cleavage factor required for 3 RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3 end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.
  • Synonyms
  • NUDT21; nudix (nucleoside diphosphate linked moiety X)-type motif 21; cleavage and polyadenylation specific factor 5, 25 kD subunit , cleavage and polyadenylation specific factor 5, 25 kDa , CPSF5; cleavage and polyadenylation specificity factor subunit
Cat.#:NUDT21-1816HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NUDT21 Protein, GST-tagged
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Cat.#:NUDT21-27532THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT21, His-tagged
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Cat.#:NUDT21-960HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT21, His-tagged
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Cat.#:NUDT21-10972MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NUDT21 Protein
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Cat.#:NUDT21-5051CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NUDT21
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Cat.#:NUDT21-3646HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NUDT21 293 Cell Lysate
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Involved Pathway

NUDT21 involved in several pathways and played different roles in them. We selected most pathways NUDT21 participated on our site, such as Cleavage of Growing Transcript in the Termination Region, Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT21 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cleavage of Growing Transcript in the Termination Region
ZFP473; ZNF473; CSTF2; SRSF11; LSM11; LSM10; CLP1; PAPOLA; U2AF2; CSTF3
Gene Expression
SUZ12B; IGF2BP1; MED23; ZNF584; SUGP1; TARBP2; LAMTOR1; ZNF192; RARAB; ZNF75A
Processing of Capped Intron-Containing Pre-mRNA
RNPS1; SLBP; SNRNP25; NXF1; CSTF3; CSTF1; HNRNPA0A; HNRNPH1; PDCD7; SRSF11
Processing of Capped Intronless Pre-mRNA
LSM10; PAPOLA; ZNF473; LSM11; NUDT21; CSTF2; SLBP; CSTF3; CLP1; ZFP473
Processing of Intronless Pre-mRNAs
CSTF2; PAPOLA; CSTF1; NUDT21; CLP1; CSTF3
RNA Polymerase II Transcription
SRSF11; CSTF2; CCNT2B; THOC4; U2AF2; CSTF1; LSM11; NUDT21; CSTF3; ZNF473
RNA Polymerase II Transcription Termination
LSM11; CSTF1; CSTF2; SLBP; RNPS1; U2AF2; PAPOLA; ZFP473; CLP1; THOC4
mRNA 3-end processing
CSTF2; NUDT21; CSTF3; SFRS3A; CLP1; SRSF11

Protein Function

NUDT21 has several biochemical functions, for example, AU-rich element binding, contributes_to RNA binding, histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT21 itself. We selected most functions NUDT21 had, and list some proteins which have the same functions with NUDT21. You can find most of the proteins on our site.
Function
Related Protein
Function AU-rich element binding
Related Protein HNRNPA0; CPSF5; ZFP36L1; ELAVL3; TIAL1; DND1; ZFP36L3; ELAVL1; ELAVL4; NUDT21
Function contributes_to RNA binding
Related Protein SMX5; NUDT21; CPSF6; LSM7
Function histone deacetylase binding
Related Protein SKOR2; NKX3-1; GCM1; BRMS1; TRAF6; YWHAE; MECP2; TOP2A; MAGEA1; MAPK8
Function hydrolase activity
Related Protein MPPED2; ATP2B3B; PTPN23A; PRSS59.2; Acr; EIF4A1A; CNOT6; KLK1B16; PGCP; PTPN11B
Function mRNA binding
Related Protein CELF1; HNRPLL; FXR2; CSTF3; NCBP2; KHSRP; PTBP2; RPS26; RC3H2; HNRNPAB
Function poly(A) RNA binding
Related Protein MRPL10; ZC3HAV1; CCAR1; EIF3I; CELF2; IFI16; NCBP2; FUS; TRNAU1AP; ATXN2
Function protein binding
Related Protein SHMT2; CDC42BPA; HIST1H2BE; MICALL2; C19orf57; TOP2A; PILRB; DYNC1LI1; TSPAN12; IFT46
Function protein homodimerization activity
Related Protein CTSE; LRP4; DMRTA1; SLC30A8; CRYAB; ZHX3; CD2; GRIK1; HEYL; XCL1

Interacting Protein

NUDT21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT21 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT21.
CPSF7; CPSF6; TRIM27; GOLGA2; RNPS1