nup35
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  • Official Full Name
  • nucleoporin 35kDa
  • Background
  • This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is part of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.
  • Synonyms
  • NUP35; nucleoporin 35kDa; nucleoporin NUP53; MP44; 35 kDa nucleoporin; Mitotic phosphoprotein 44; MP 44; NP 44; NP44; Nuclear pore complex protein 53kDa; Nuclear pore complex protein Nup 53; Nuclear pore complex protein Nup53; Nuclear pore protein NUP 53; Nuclear pore protein NUP53; Nucleoporin 53kDa; Nucleoporin Nup 35; Nucleoporin NUP 53; Nucleoporin Nup35; NUP 35; Nup 53; MP-44; NUP53
Cat.#:NUP35-1979HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human NUP35 Protein, MYC/DDK-tagged
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Cat.#:NUP35-1486HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUP35 protein, His & T7-tagged
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Cat.#:NUP35-10995MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NUP35 Protein
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Cat.#:NUP35-4127RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NUP35 Protein
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Cat.#:NUP35-3137RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NUP35 Protein, His-tagged
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Cat.#:NUP35-10420ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NUP35
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Cat.#:NUP35-1231HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human NUP35 cell lysate
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Involved Pathway

NUP35 involved in several pathways and played different roles in them. We selected most pathways NUP35 participated on our site, such as Antiviral mechanism by IFN-stimulated genes, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP35 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Antiviral mechanism by IFN-stimulated genes
JAK1; IFIT8; EIF4A1; DPF1; EIF4A2; KPNA4; IFIT10; KPNA5; ARIH1; NUP50
Cell Cycle
NEDD1; MCM4; ACD; FZR1A; ESCO1; TEX15; KIF2C; BLZF1; WAPAL; CENPH
Cell Cycle, Mitotic
SKA2; CENPI; BLZF1; SKA1; SPC25; NCAPD3; CDCA8; MCPH1; CSNK2A2; CEP164
Cellular response to heat stress
RPS19BP1; DNAJC7; HSBP1; DNAJC2; BAG3; HSPA7; HSBP1A; C11orf73; NUPL2; DNAJB6
Cellular responses to stress
IGFBP7; MOV10; MAP1LC3B; AGO1; GABARAPL2; NUP35; DYNLL2A; KDM6B; EHMT2; DNAJC2
Cytokine Signaling in Immune system
PELI3; IRAK3; SPTBN1; IRF9; PRLRB; GBP5; TRIM3; CRKL; SPTB; TNFSF13B
Disease
KPNA5; CCDC167; KREMEN2; MTRR; RNF43; ACAN; RBP1; TNKS; AP2M1; NMT1
Export of Viral Ribonucleoproteins from Nucleus
DPF1; NUP35; NUPL2; NUP50

Protein Function

NUP35 has several biochemical functions, for example, nucleocytoplasmic transporter activity, phospholipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP35 itself. We selected most functions NUP35 had, and list some proteins which have the same functions with NUP35. You can find most of the proteins on our site.
Function
Related Protein
Function nucleocytoplasmic transporter activity
Related Protein NUP107; NUP160; NUP54; RBM22; XPO1; UPF3A; NUP214; NUPL1; TPR; TPRB
Function phospholipid binding
Related Protein APOA1; BAIAP2L2; ARHGAP44; HIP1RB; SDPR; LRBA; SEC14L2; SPTBN2; PSD4; ABCA1
Function protein binding
Related Protein VASH1; LARP7; ISL1; CYTIP; KCND2; NFATC4; POLR1B; C1orf182; DDR2; NTRK1
Function single-stranded DNA binding
Related Protein MCM4; PEO1; IGHMBP2; PMS1; RPA4; MCM7; SSBP4; ERCC4; PURA; SSBP3

Interacting Protein

NUP35 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP35 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP35.
KCTD9; saicar; PKM; AHCTF1; v-bcl-2; Kifc5b; NUP153; NUP107; UBE2I; Ube2i; KPNB1; Nup98; Nup214; Nup107; Rcc1; SEH1L; Nup155; NUPL1

NUP35 Related Articles

Eisenhardt, N; Redolfi, J; et al. Interaction of Nup53 with Ndc1 and Nup155 is required for nuclear pore complex assembly. JOURNAL OF CELL SCIENCE 127:908-921(2014).
Vollmer, B; Schooley, A; et al. Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly. EMBO JOURNAL 31:4072-4084(2012).