• Official Full Name
  • nidogen 2
  • Background
  • Nidogen-2 is a protein that in humans is encoded by the NID2 gene. Basement membranes, which are composed of type IV collagens (see MIM 120130), laminins (see LAMC1; MIM 150290), perlecan (HSPG2; MIM 142461), and nidogen (see NID1; MIM 131390), are thin pericellular protein matrices that control a large number of cellular activities, including adhesion, migration, differentiation, gene expression, and apoptosis.[supplied by OMIM
  • Synonyms
  • Nid2; nidogen2; Ly111; NID-2; AW547149; nidogen-2; entactin-2; osteonidogen2; nidogen 2 (osteonidogen)
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NID2 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NID2 Protein
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Nid2 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NID2 Protein
Source (Host):Species:Human
Product nameRecombinant Human NID2 cell lysate

Involved Pathway

NID2 involved in several pathways and played different roles in them. We selected most pathways NID2 participated on our site, such as Extracellular matrix organization, Laminin interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with NID2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Extracellular matrix organization
LOC100686744; ADAM15; LEPRE1; COL17A1A; HAPLN1; CEACAM1; F11R.2; LAMC3; COL28A1D; MGC174152
Laminin interactions

Protein Function

NID2 has several biochemical functions, for example, calcium ion binding, collagen binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NID2 itself. We selected most functions NID2 had, and list some proteins which have the same functions with NID2. You can find most of the proteins on our site.
Related Protein
Function calcium ion binding
Related Protein EFHA1; CALN1; MYL2; S100A1; PCDHB5; CLEC3B; CDH16; CDH12; PCDH2G2; ITSN2A
Function collagen binding
Related Protein PODN; ITGA9; ABI3BP; SERPINH1B; DDR2; Pdgfa&Pdgfb; SMAD3; GP5; Itga10&Itgb1; ITGA1
Function protein binding
Related Protein TNIK; PARL; ATP5O; BMP1; CPNE6; GTPBP3; BTK; CCDC47; DPH2; DLG4

Interacting Protein

NID2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NID2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NID2.
SKIL; q9wmx2-pro_0000037548

NID2 Related Articles

Britze, A; Birkler, RID; et al. Large-Scale Proteomics Differentiates Cholesteatoma from Surrounding Tissues and Identifies Novel Proteins Related to the Pathogenesis. PLOS ONE 9:-(2014).
Maldonado, L; Brait, M; et al. An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine. ONCOTARGET 5:5218-5233(2014).