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OASL

  • Official Full Name

    2-5-oligoadenylate synthetase-like

  • Overview

    59 kDa 2-5-oligoadenylate synthetase-like protein is an enzyme that in humans is encoded by the OASL gene.
  • Synonyms

    OASL; 2-5-oligoadenylate synthetase-like; 59 kDa 2-5-oligoadenylate synthase-like protein; p59OASL; TRIP14; TRIP-14; p59 OASL; TR-interacting protein 14; thyroid receptor-interacting protein 14; 59 kDa 2-5-oligoadenylate synthetase-like protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • C
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human OASL-521H Recombinant Human OASL Protein, His-tagged E.coli His
Human OASL-3612HCL Recombinant Human OASL 293 Cell Lysate HEK293 N/A
Human OASL-5230H Recombinant Human OASL Protein (Met1-Trp244), N-His tagged E.coli N-His Met1-Trp244
Human OASL-310H Recombinant Human OASL Protein, His-tagged E.coli His Ala2~Trp244
Human OASL-5229H Recombinant Human OASL Protein (Met1-His100), C-His tagged E.coli C-His Met1-His100
Rat OASL-4146R Recombinant Rat OASL Protein Mammalian Cell His
Rat OASL-3808R Recombinant Rat OASL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat OASL-3808R-B Recombinant Rat OASL Protein Pre-coupled Magnetic Beads HEK293
Chicken OASL-6598C Recombinant Chicken OASL Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • OASL Related Articles
  • OASL Related Gene Family

OASL involved in several pathways and played different roles in them. We selected most pathways OASL participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with OASL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine Signaling in Immune systemKPNA3;EIF4EB;TRIM14;IFITM3;NOD1;ADAR;TRIM38;RASGEF1A;ISG20
Immune SystemMICA;FCN2;ASB2;KIF11;LILRA3;TLR10;PANX1B;ABI2;DTX3L
Interferon SignalingTRIM6;IFIT8;OASL;IRF6;TRIM29;IRF2;IFIT14;IRF9;ISG20
Interferon alpha/beta signalingIFIT2;BST2;IFITM2;SAMHD1;IRF4;IRF2;USP18;IFITM3;ISG20
Interferon gamma signalingTRIM31;GBP5;TRIM14;IRF4;TRIM8;TRIM26;TRIM48;TRIM17;GBP6

OASL has several biochemical functions, for example, NOT 2-5-oligoadenylate synthetase activity, ATP binding, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OASL itself. We selected most functions OASL had, and list some proteins which have the same functions with OASL. You can find most of the proteins on our site.

Function Related Protein
NOT 2-5-oligoadenylate synthetase activityOASL;OAS1B;OASL1
ATP bindingABCC12;PSMC3;MAPKAPK2B;MAGI1;GSG2;CHKB;DDX46;CSNK1G2;IKBKE
DNA bindingNR6A1A;INSM2;POLR2J3;NFYAL;MAFA;HIST1H2AA;LASS5;ZNF692;PBX1
double-stranded RNA bindingDHX58;PRKRIP1;RFTN1;SLC3A2;LRRFIP1;IFIH1;OAS1B;HMGB1;DDX58
poly(A) RNA bindingHIST1H1E;STRAP;PDIA4;FYTTD1;ISG20L2;OTUD4;FSCN1;HOXB6;ALDOA
thyroid hormone receptor bindingMED4;TAF7;MED30;NR0B2;TAF11;ZNHIT3;MED17;MED13;GAS2L1

OASL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OASL here. Most of them are supplied by our site. Hope this information will be useful for your research of OASL.

SEZ6L2; CD14; Map9; TMEM63B; Spire2; Klc3; TM9SF4; SORT1

Feng, XB; Huang, J; et al. Identification of interferon-inducible genes as diagnostic biomarker for systemic lupus erythematosus. CLINICAL RHEUMATOLOGY 34:71-79(2015).
Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).
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