oasl
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  • Official Full Name
  • 2-5-oligoadenylate synthetase-like
  • Background
  • 59 kDa 2-5-oligoadenylate synthetase-like protein is an enzyme that in humans is encoded by the OASL gene.
  • Synonyms
  • OASL; 2-5-oligoadenylate synthetase-like; 59 kDa 2-5-oligoadenylate synthase-like protein; p59OASL; TRIP14; TRIP-14; p59 OASL; TR-interacting protein 14; thyroid receptor-interacting protein 14; 59 kDa 2-5-oligoadenylate synthetase-like protein
Cat.#:OASL-310HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human OASL Protein, His-tagged
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Cat.#:OASL-521HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human OASL Protein, His-tagged
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Cat.#:OASL-4146RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat OASL Protein
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Cat.#:OASL-6598CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken OASL
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Cat.#:OASL-3612HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human OASL 293 Cell Lysate
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Involved Pathway

OASL involved in several pathways and played different roles in them. We selected most pathways OASL participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with OASL were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
IFI30; KLB; DUSP1; OASL; TRIM31; TRIM5; CASPB; DPF1; EGR1; SPNA2
Immune System
TXNIP; SIRPB1; CLEC2D; DUSP3B; DEFA3; KLRB1B; TRIM6; CR1; MKRN1; HCST
Interferon Signaling
HERC5; IFI6; IFIT8; GBP4; TRIM26; TRIM10; IFITM3; IFIT2; OASL; IFIT3
Interferon alpha/beta signaling
MX2; SAMHD1; IFITM2; IRF4; IRF9; IFI35; XAF1; IFIT2; IFIT3; ISG20
Interferon gamma signaling
TRIM8; IFI30; TRIM6; TRIM38; GBP2; GBP4; TRIM45; TRIM31; GBP5; TRIM5

Protein Function

OASL has several biochemical functions, for example, NOT 2-5-oligoadenylate synthetase activity, ATP binding, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OASL itself. We selected most functions OASL had, and list some proteins which have the same functions with OASL. You can find most of the proteins on our site.
Function
Related Protein
Function NOT 2-5-oligoadenylate synthetase activity
Related Protein OASL; OAS1B; OASL1
Function ATP binding
Related Protein MYO5B; DDX56; PRKX; LYN; FARSB; UBE2R2; NLRP9B; MTHFD1B; DHX30; SLFN5
Function DNA binding
Related Protein HOXC6B; PARPBP; MCMDC2; ILF3B; LEMD3; ZBED3; RNF4; ELK4; EME2; FOXG1
Function double-stranded RNA binding
Related Protein LRRFIP1; STAU2; DROSHA; ELAVL1; OASL2; RNASEN; AGO1; DDX58; OAS1B; AGO3
Function poly(A) RNA binding
Related Protein POP1; RPS21; SRP54B; PNN; SAFB; TRIM28; DHX32; CPEB2; RSL1D1; DDX54
Function thyroid hormone receptor binding
Related Protein PRMT2; TAF11; OASL; NCOA3; MED13; MED30; MED12; NUP62; MED24; GAS2L1

Interacting Protein

OASL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OASL here. Most of them are supplied by our site. Hope this information will be useful for your research of OASL.
SEZ6L2; CD14; Map9; TMEM63B; Spire2; Klc3; TM9SF4; SORT1

OASL Related Articles

Feng, XB; Huang, J; et al. Identification of interferon-inducible genes as diagnostic biomarker for systemic lupus erythematosus. CLINICAL RHEUMATOLOGY 34:71-79(2015).
Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).

OASL Related Gene Family

Cytokines