pdia6
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  • Official Full Name
  • protein disulfide isomerase family A, member 6
  • Background
  • Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that;catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in;folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 (PubMed 7590364)).
  • Synonyms
  • PDIA6; protein disulfide isomerase family A, member 6; protein disulfide isomerase associated 6 , thioredoxin domain containing 7 (protein disulfide isomerase) , TXNDC7; protein disulfide-isomerase A6; ERp5; P5; protein disulfide isomerase related protein; Endoplasmic reticulum protein 5; Protein disulfide isomerase A6; Protein disulfide isomerase associated 6; Protein disulfide isomerase family A member 6; Protein disulfide isomerase P5; Thioredoxin domain containing 7 (protein disulfide isomerase); Thioredoxin domain containing protein 7; TXNDC7; ER protein 5; thioredoxin domain-containing protein 7; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein
Cat.#:PDIA6-2856HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDIA6, His-tagged
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Cat.#:PDIA6-118HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDIA6, MYC/DDK-tagged
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Cat.#:PDIA6-124HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDIA6, His-tagged
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Cat.#:PDIA6-1618HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDIA6, GST-tagged
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Cat.#:PDIA6-22HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDIA6 protein, His-tagged
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Cat.#:PDIA6-29136THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDIA6, His-tagged
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Cat.#:PDIA6-4347RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PDIA6 Protein
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Cat.#:PDIA6-3359RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PDIA6 Protein, His-tagged
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Cat.#:PDIA6-3330HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDIA6 293 Cell Lysate
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Involved Pathway

PDIA6 involved in several pathways and played different roles in them. We selected most pathways PDIA6 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDIA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
IRE1alpha activates chaperones
TPP1; CXXC1; CTDSP2; SEC63; ADD1; DDX11; SERP1; HYOU1; KLHDC3; KDELR3
Metabolism of proteins
RAB27A; IGF2B; TMED10; HDGF; SPON1B; HYOU1; IGFBP1A; SEC23IP; NAPB; IGFBP6A
Protein processing in endoplasmic reticulum
STT3B; HSPA4L; CALR3B; UBE2J2; SEC23B; DNAJC5GA; WFS1; CAPN2L; HSP26; RRBP1A
Unfolded Protein Response (UPR)
C19orf10; SERP1; PDIA6; YIF1A; DDX11; SEC63; ASNA1; KLHDC3; WIPI1; HYOU1
XBP1(S) activates chaperone genes
HYOU1; KLHDC3; FKBP14; TPP1; YIF1A; DDX11; SEC63; KDELR3; CTDSP2; WIPI1

Protein Function

PDIA6 has several biochemical functions, for example, protein binding, protein disulfide isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDIA6 itself. We selected most functions PDIA6 had, and list some proteins which have the same functions with PDIA6. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein H3F3B; APOE; CLDN8; SSX5; CNTF; H2AFX; TRMT61B; HSPB9; TRAPPC2L; PROC
Function protein disulfide isomerase activity
Related Protein PDIA2; TMX3; TXNDC11; PDIA6; ERO1L; GLRX2; PIGK; PDIA5; QSOX1; P4HB

Interacting Protein

PDIA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDIA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDIA6.
PRDX4; gag-pol; ganglioside_gm1; NME2; IKBKE; Bles03; TNFRSF14; PRKAB1; TRAF6; Dnajb9; CASP8; Dnajc10; Dnajb11; q81k28_bacan; q99ib8-pro_0000045599; ATP13A2; q9wmx2-pro_0000037550; gd3