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PEX16

  • Official Full Name

    peroxisomal biogenesis factor 16

  • Overview

    The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.
  • Synonyms

    PEX16; peroxisomal biogenesis factor 16; Peroxin 16; Peroxin16; Peroxisomal membrane protein PEX16; PEX 16; peroxin-16; peroxisome biogenesis factor 16;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Arabidopsis thaliana (Mouse-ear cress)
  • Bos taurus (Bovine)
  • Danio rerio (Zebrafish) (Brachydanio rerio)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Xenopus laevis (African clawed frog)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PEX16-3290HCL Recombinant Human PEX16 293 Cell Lysate HEK293 N/A
Human PEX16-3291HCL Recombinant Human PEX16 293 Cell Lysate HEK293 N/A
Mouse PEX16-12649M Recombinant Mouse PEX16 Protein Mammalian Cell His
Mouse Pex16-4797M Recombinant Mouse Pex16 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PEX16-6646M Recombinant Mouse PEX16 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PEX16-6646M-B Recombinant Mouse PEX16 Protein Pre-coupled Magnetic Beads HEK293
Arabidopsis thaliana (Mouse-ear cress) RFL26517AF Recombinant Full Length Arabidopsis Thaliana Peroxisome Biogenesis Protein 16(Pex16) Protein, His-Tagged E.coli expression system His Full Length (1-367)
Bos taurus (Bovine) RFL6682BF Recombinant Full Length Bovine Peroxisomal Membrane Protein Pex16(Pex16) Protein, His-Tagged E.coli expression system His Full Length (1-328)
Danio rerio (Zebrafish) (Brachydanio rerio) RFL24999DF Recombinant Full Length Danio Rerio Peroxisomal Membrane Protein Pex16(Pex16) Protein, His-Tagged E.coli expression system His Full Length (1-335)
Homo sapiens (Human) RFL34512HF Recombinant Full Length Human Peroxisomal Membrane Protein Pex16(Pex16) Protein, His-Tagged E.coli expression system His Full Length (1-336)
Mus musculus (Mouse) RFL28727MF Recombinant Full Length Mouse Peroxisomal Membrane Protein Pex16(Pex16) Protein, His-Tagged E.coli expression system His Full Length (1-336)
Xenopus laevis (African clawed frog) RFL19414XF Recombinant Full Length Xenopus Laevis Peroxisomal Membrane Protein Pex16(Pex16) Protein, His-Tagged E.coli expression system His Full Length (1-340)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL27982XF Recombinant Full Length Xenopus Tropicalis Peroxisomal Membrane Protein Pex16(Pex16) Protein, His-Tagged E.coli expression system His Full Length (1-340)
Zebrafish PEX16-3074Z Recombinant Zebrafish PEX16 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PEX16 Related Articles

PEX16 involved in several pathways and played different roles in them. We selected most pathways PEX16 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEX16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PeroxisomeMPV17L2;HMGCLL1;PEX16;PEX1;DAO.1;ACOX3;NOS2;ACSL1A;PAOX

PEX16 has several biochemical functions, for example, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEX16 itself. We selected most functions PEX16 had, and list some proteins which have the same functions with PEX16. You can find most of the proteins on our site.

Function Related Protein
protein C-terminus bindingTERF2;XRCC6;SLC9A3R2;TOP2B;MIF4GD;DDX1;DLG3;AP2A1;FOXN3
protein bindingDKC1;C4BPB;NME4;PPCDC;GCNT1;PRPF8;P2RY1;NPBWR2;TDG

PEX16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEX16 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEX16.

PEX19; PEX3; PEX14

Liu, JB; Yu, B; et al. Effects of intrauterine growth retardation and maternal folic acid supplementation on hepatic mitochondrial function and gene expression in piglets. ARCHIVES OF ANIMAL NUTRITION 66:357-371(2012).
Nedeau, AE; Gallagher, KA; et al. Elevation of hemopexin-like fragment of matrix metalloproteinase-2 tissue levels inhibits ischemic wound healing and angiogenesis. JOURNAL OF VASCULAR SURGERY 54:1430-1438(2011).
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