pkd2l1
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  • Official Full Name
  • polycystic kidney disease 2-like 1
  • Background
  • This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane;domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in;cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two;transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • PKD2L1; polycystic kidney disease 2-like 1; PKD2L, PKDL; polycystic kidney disease 2-like 1 protein; PCL; transient receptor potential cation channel; subfamily P; member 3; TRPP3; B830002B15; BC046386; PK2L1; PK2L1_HUMAN; PKD2L; PKDL; Polycystic kidney disease 2 like 1 protein; Polycystin L; Polycystin-2 homolog; Polycystin-2L1; Polycystin-L; Polycystin-L1; transient receptor potential cation channel, subfamily P, member 3
Cat.#:PKD2L1-1739HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PKD2L1, GST-tagged
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Cat.#:PKD2L1-12861MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PKD2L1 Protein
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Protein Function

PKD2L1 has several biochemical functions, for example, alpha-actinin binding, calcium activated cation channel activity, calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PKD2L1 itself. We selected most functions PKD2L1 had, and list some proteins which have the same functions with PKD2L1. You can find most of the proteins on our site.
Function
Related Protein
Function alpha-actinin binding
Related Protein ADORA2A; RARA; KCNN2; MYOT; XIRP2; DAG1; PKD2L1; KCNA5; PPARG; MAGI1
Function calcium activated cation channel activity
Related Protein TMEM63C; TRPM4A; TRPM4; CATSPER1; CALHM1; TRPM5; CATSPER2; ANO10; TRPM4C; ANO6
Function calcium channel activity
Related Protein TRPV1; CACNA1C; PSEN1; TRPM8; TRPM4; MCU; CACNG2A; TRPC4B; GRIN2B; TRPC3
Function calcium ion binding
Related Protein CRP; PCDH1G22; GALNT3; NOTCH2; SYT6; CAMKK2; DSC2L; S100P; SYT3; ANXA2B
Function calcium-activated potassium channel activity
Related Protein KCNMB3; KCNN1A; KCNMB2; KCNT1; KCNMA1; HPN; KCNMA1A; KCNMB4; KCNMB1; KCNN1
Function cation channel activity
Related Protein TRPC1; TRPV2; ASIC3; FAM26D; GRIN2C; ASIC4A; ACCN3; PKD1; FAM38A; TRPM1A
Function contributes_to cation transmembrane transporter activity
Related Protein PKD1L3; PKD2L1
Function cytoskeletal protein binding
Related Protein DES; PKD2L1; PTPN4A; MYPN; EPB41B; B4GALT1; EPB4.1L4A; ALDOC; ANXA2A; CORO1A
Function identical protein binding
Related Protein PKD2; GRB2; MPZL2B; RASSF1; SSNA1; BRAP; VPS4B; P2RX6; HCN2; NFKB1
Function muscle alpha-actinin binding
Related Protein PKD2L1; TTN; NRAP; PALLD; MYPN; PKD2; LDB3; PDLIM2
Function protein binding
Related Protein RPS19; TRAP1; LRR1; MYOCD; CDC40; HTR3E; PAPD4; FKBP3; EGF; CENPT
Function sodium channel activity
Related Protein ASIC1A; PKD2L1; SLC4A11; SCN4AA; SCN8AB; SCN11A; ASIC4A; SCN8AA; SCNN1G; ASIC1B
Function contributes_to sour taste receptor activity
Related Protein PKD1L3; PKD2L1

Interacting Protein

PKD2L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKD2L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PKD2L1.
PKD1L3