pla2g4c
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  • Official Full Name
  • phospholipase A2, group IVC (cytosolic, calcium-independent)
  • Background
  • Cytosolic phospholipase A2 (cPLA2) is a ubiquitously distributed enzyme that catalyzes the hydrolysis of the sn-2 acyl bond of glycerolipids to produce lysophospholipids and release arachidonic acid. cPLA2 has been implicated in diverse cellular responses
  • Synonyms
  • PLA2G4C; phospholipase A2, group IVC (cytosolic, calcium-independent); cytosolic phospholipase A2 gamma; cPLA2 gamma; phospholipase A2 group IVC; CPLA2-gamma; FLJ42247; FLJ44164; DKFZp586C0423
Cat.#:PLA2G4C-1753HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLA2G4C, His-tagged
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Cat.#:PLA2G4C-3140HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PLA2G4C 293 Cell Lysate
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Involved Pathway

PLA2G4C involved in several pathways and played different roles in them. We selected most pathways PLA2G4C participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycerophospholipid metabolism
CHPT1; LCLAT1; PPAP2D; ADPRM; ETNPPL; CDIPT; PLA2G1B; LYPLA2; CHATA; AGPAT5
Ether lipid metabolism
PLA2G4B; AGPS; PLB1; PAFAH2; PPAP2A; GAL3ST1; PLA2G10; GAL3ST1A; PLA2G3; PLA2G4A
Arachidonic acid metabolism
CYP2C8; CYP1B1; CYP2B19; CYP2P9; PLA2G4A; AWAT1; CYP2C54; ALOX8; CYP2AD6; GGT5A
Linoleic acid metabolism
PLA2G2D; PLA2G4A; PLA2G12B; CYP2P10; PLA2G2E; CYP2P6; CYP2C50; PLA2G4C; CYP2J2; PLA2G12A
alpha-Linolenic acid metabolism
PLA2G12B; ACOX1; PLA2G2E; PLA2G4F; PLA2G3; FADS2; PLA2G4A; ACOX3; PLA2G1B; PLA2G6
Metabolic pathways
MOGS; PCYT2; GK; NAT2; BDH2; NAPRT; NDUFS8B; MT-ND4; ACLYA; ADSS
MAPK signaling pathway
MAPK11; AKT2; NLK2; MAPK1; TGFB1A; CDC42L2; ELK1; MECOM; FGF13A; RRAS
Ras signaling pathway
FGFR3; CALML5; PLA2G4D; RASAL2; CALM2; PLD2; PIK3R3; AKT1; GNG11; GNG13
Phospholipase D signaling pathway
INS1; GRM2; DGKZ; CYTH2; SHC2; PPAP2C; AKT1; PIK3R5; GRM6; IL-8
Vascular smooth muscle contraction
ITPR3; MYL6; ROCK2B; MAP2K2B; PRKCBA; KCNMA1A; PLA2G2D; NPR1A; PLA2G2E; CALM
VEGF signaling pathway
PLA2G4F; PIK3R2; MAPK14A; MAPK14B; PPP3R1; NRAS; PTGS2A; PIK3CD; AKT1; MAPK3
Platelet activation
PRKACA; MAPK13; ROCK2; ITPR1; AKT2; TBXAS1; APBB1IP; Adcy4; F2RL3; MYL12A
Fc epsilon RI signaling pathway
GM-CSF; FCER1G; MAP2K7; PLCG2; VAV1; IL5; TNF; RAF1; AKT1; PLA2G4A
Glutamatergic synapse
SHANK2; GNG10; GNG8; PPP3R1; PRKCG; SLC1A2; GRIK4; GNG5; GRIN2B; SLC38A2
Serotonergic synapse
MAOB; CYP2J5; KRAS; TRPC1; ALOX12B; GNAO1; HTR4; HTR2B; GNB2; GNG13
Long-term depression
GNAQ; GUCY1A3; MAP2K1; PLCB4; GNA12; GNAI2; PLCB1; RAF1; ARAF; ITPR3
Inflammatory mediator regulation of TRP channels
PRKCB; MAPK10; ACCN5; PRKCD; MAPK9; PIK3CG; PTGER2; CYP2J5; ALOX12; MAPK8
GnRH signaling pathway
CDC42; LHBETA1; PRKCD; PRKACG; ELK1; GNRH2; MAP2K4B; PRKACAB; MAP3K1; CALM2
Ovarian steroidogenesis
LDLR; PLA2G4A; GNAS; FSHR; CYP2J5; GDF9; HSD3B1; HSD3B6; HSD3B2; HSD17B2
Oxytocin signaling pathway
PLA2G4C; PRKAG2; CACNG6; GNAI2; PIK3R2; CACNG4; ROCK1; MYLK; GNAS; PPP1R12B
Choline metabolism in cancer
PPAP2B; SLC22A2; WASF2; PIK3CD; SOS1; KRAS; PDGFC; RAC2; SLC22A1; PIK3R2

Protein Function

PLA2G4C has several biochemical functions, for example, calcium-independent phospholipase A2 activity, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4C itself. We selected most functions PLA2G4C had, and list some proteins which have the same functions with PLA2G4C. You can find most of the proteins on our site.
Function
Related Protein
Function calcium-independent phospholipase A2 activity
Related Protein PLA2G15; PLA2G7; PNPLA8; PLA2G4C
Function phospholipid binding
Related Protein APOA1; F10; ANXA9; PAFAH2; NBEAA; GOT2; STAP1; SHC1; APOEB; PLA2G2A