PLA2G4C

  • Official Full Name

    phospholipase A2, group IVC (cytosolic, calcium-independent)
  • Overview

    Cytosolic phospholipase A2 (cPLA2) is a ubiquitously distributed enzyme that catalyzes the hydrolysis of the sn-2 acyl bond of glycerolipids to produce lysophospholipids and release arachidonic acid. cPLA2 has been implicated in diverse cellular responses
  • Synonyms

    PLA2G4C;phospholipase A2, group IVC (cytosolic, calcium-independent);cytosolic phospholipase A2 gamma;cPLA2 gamma;phospholipase A2 group IVC;CPLA2-gamma;FLJ42247;FLJ44164;DKFZp586C0423
Cat.# Product name Source (Host) Species Tag Protein Length Price
PLA2G4C-1753H Recombinant Human PLA2G4C, His-tagged E.coli Human His 190-541aa
PLA2G4C-3140HCL Recombinant Human PLA2G4C 293 Cell Lysate HEK293 Human Non

    Involved Pathway

    PLA2G4C involved in several pathways and played different roles in them. We selected most pathways PLA2G4C participated on our site, such as Glycerophospholipid metabolism,Ether lipid metabolism,Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism CYP2J2,PTGS2B,FAAH2A,TBXAS1,PLA2G2E,AWAT2,CYP1B1,ALOX12B,PLA2G12B,CBR2
    Platelet activation GNAS,RHOA,TBXA2R,Adcy4,PIK3CB,RAP1A,MAPK13,ITGA2,ROCK1,P2RY1
    Fc epsilon RI signaling pathway PLA2G4A,PIK3CB,PLCG2,MAPK1,PLCG1,PIK3CD,MAPK9,IL4,MAPK13,MAP2K3
    Serotonergic synapse HTR4,GNB4,CYP2D10,GNG5,PTGS1,CYP2D9,HTR1F,PRKACG,PLCB2,GNAI1
    alpha-Linolenic acid metabolism PLA2G2F,PLA2G3,ACAA1A,ACOX3,PLA2G2E,PLA2G12B,PLA2G4A,PLA2G12A,PLA2G2D,FADS2
    GnRH signaling pathway FSHB,PLA2G4A,CALM1A,MAP2K7,PLA2G4AA,PRKCB,HBEGFA,CALML5,ITPR1,CACNA1DA
    Glycerophospholipid metabolism LYCAT,LCAT,CRLS1,CEPT1,GPD1A,PCYT1BB,CDS1,AGPAT5,CHKA,ETNK2
    MAPK signaling pathway FGF5,FGF17,MAP2K2A,FGF6,MAP2K7,DUSP8A,MAP4K3,FGF13,PPP3CA,FGF10
    Inflammatory mediator regulation of TRP channels CALM1,TRPM8,PIK3CB,PTGER4,ACCN5,NTRK1,CYP2J2,CYP2C37,CYP2J6,PLCB1

    Protein Function

    PLA2G4C has several biochemical functions, for example, calcium-independent phospholipase A2 activity,phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4C itself. We selected most functions PLA2G4C had, and list some proteins which have the same functions with PLA2G4C. You can find most of the proteins on our site.

    Function Related Protein
    phospholipid binding ABCA1,APOEB,CPS1,SYT14,PLA2G2A,DGKA,APOM,AGAP1,Defa4,GOT2
    calcium-independent phospholipase A2 activity PLA2G15,PLA2G7,PNPLA8

    Interacting Protein

    PLA2G4C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G4C here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G4C.

    Resources

    References

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