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PLA2G4C

Official Full Name

phospholipase A2, group IVC (cytosolic, calcium-independent)
Overview

Cytosolic phospholipase A2 (cPLA2) is a ubiquitously distributed enzyme that catalyzes the hydrolysis of the sn-2 acyl bond of glycerolipids to produce lysophospholipids and release arachidonic acid. cPLA2 has been implicated in diverse cellular responses
Synonyms

PLA2G4C; phospholipase A2, group IVC (cytosolic, calcium-independent); cytosolic phospholipase A2 gamma; cPLA2 gamma; phospholipase A2 group IVC; CPLA2-gamma; FLJ42247; FLJ44164; DKFZp586C0423;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PLA2G4C-1753H	Recombinant Human PLA2G4C, His-tagged	E.coli	His	190-541aa	$319 / 25ug
Human	PLA2G4C-3140HCL	Recombinant Human PLA2G4C 293 Cell Lysate	HEK293	N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PLA2G4C involved in several pathways and played different roles in them. We selected most pathways PLA2G4C participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycerophospholipid metabolism	CEPT1B;PLA2G10;LPCAT2;PLA2G3;PLA2G5;DGKB;CHAT;PPAP2C;AGPAT9L
Ether lipid metabolism	ENPP6;PAFAH1B1A;PLA2G4D;PLA2G1B;PLA2G2D;PAFAH1B1B;PLA2G7;CHPT1;PLA2G6
Arachidonic acid metabolism	PTGS1;CBR3;PLA2G16;HPGDS;PTGS2B;GPX1A;PLA2G2A;AWAT2;PLA2G4AA
Linoleic acid metabolism	CYP2C45;DHRS13L1;PLA2G2A;CYP2C50;PLA2G4C;PLA2G2F;PLA2G4AA;PLA2G10;CYP2C9
alpha-Linolenic acid metabolism	FADS2;PLA2G3;PLA2G4F;PLA2G4D;PLA2G4A;ACAA1A;ACOX3;PLA2G6;PLA2G1B
Metabolic pathways	POLR3GLB;ST6GALNAC1;NOS2B;ME3;R05D11.9;PAPSS2;GCNT4;Acsm2a;PFKL
MAPK signaling pathway	MAPK13;FGF10A;FGFR1;PAK2A;FGF11A;FGF20B;PTPN7;TRAF2;MAPK8IP2
Ras signaling pathway	PIK3R3;FLT1;ANGPT1;SHC1;PLA2G2F;PLA2G6;GNG3;PAK6;RASA1
Phospholipase D signaling pathway	SHC3;CXCR1;RHOA;KIT;AGTR1A;PTK2B;INS1;PLA2G4F;GRM6
Vascular smooth muscle contraction	CACNA1DA;MYLK4;GNAQ;GNA15.4;PRKCHA;MYL9B;PRKACG;CALM3B;CALM2B
VEGF signaling pathway	CDC42L;CASP9;PRKCBA;NOS3;NFATC2;RAC3B;PRKCG;PIK3R5;VEGFAA
Platelet activation	PRKG2;PLCB2;F2RL3;VAMP8;FGA;GNAI3;PLA2G4F;ITGB1;PIK3CB
Fc epsilon RI signaling pathway	VAV1;MAP2K1;LAT;PIK3CA;GAB2;IL3;RAC1;PLA2G4F;GM-CSF
Glutamatergic synapse	PRKACA;GNAI2;GRIN2A;MAPK3;GNB3;HOMER2;SHANK2;GNG10;SLC1A7
Serotonergic synapse	HTR1F;Casp3;GNB2;GABRB3;GNAI2;CYP2C70;PLA2G4C;ALOX5;PTGS1
Long-term depression	BRAF;LYN;GNA12;ITPR3;PPP2R1A;PRKG1;ITPR1;GNAS;PLCB1
Inflammatory mediator regulation of TRP channels	ITPR3;HRH1;MAPK11;CYP2C54;PRKACG;MAPK9;ACCN5;CAMK2G;PIK3R3
GnRH signaling pathway	RAF1A;PRKCDA;MAPK14B;PLCB4;MAP3K1;CALM3;PRKACB;PLA2G4AA;CAMK2G
Ovarian steroidogenesis	SCARB1;GNAS;HSD3B5;LHCGR;HSD17B1;HSD3B2;HSD3B6;CYP2J5;HSD17B7
Oxytocin signaling pathway	PRKACG;MYL6;PPP3R2;MAPK3;CAMK1;MAPK1;PPP3CC;GUCY1B3;PRKAA2
Choline metabolism in cancer	PDGFA;SLC22A3;HRAS;PIK3CB;MAPK9;PLA2G4C;RALGDS;PDGFRB;MAPK8

PLA2G4C has several biochemical functions, for example, calcium-independent phospholipase A2 activity, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4C itself. We selected most functions PLA2G4C had, and list some proteins which have the same functions with PLA2G4C. You can find most of the proteins on our site.

Function	Related Protein
calcium-independent phospholipase A2 activity	PLA2G7;PNPLA8;PLA2G15;PLA2G4C
phospholipid binding	PREX1;F3;ARHGAP26;PICALMB;AMPH;APOEA;FABP1;CPS1;Defa4

PLA2G4C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G4C here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G4C.