pla2g4c
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  • Official Full Name
  • phospholipase A2, group IVC (cytosolic, calcium-independent)
  • Background
  • Cytosolic phospholipase A2 (cPLA2) is a ubiquitously distributed enzyme that catalyzes the hydrolysis of the sn-2 acyl bond of glycerolipids to produce lysophospholipids and release arachidonic acid. cPLA2 has been implicated in diverse cellular responses
  • Synonyms
  • PLA2G4C; phospholipase A2, group IVC (cytosolic, calcium-independent); cytosolic phospholipase A2 gamma; cPLA2 gamma; phospholipase A2 group IVC; CPLA2-gamma; FLJ42247; FLJ44164; DKFZp586C0423
Cat.#:PLA2G4C-1753HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLA2G4C, His-tagged
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Cat.#:PLA2G4C-3140HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PLA2G4C 293 Cell Lysate
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Involved Pathway

PLA2G4C involved in several pathways and played different roles in them. We selected most pathways PLA2G4C participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4C were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycerophospholipid metabolism
LPIN2; PLA2G5; MBOAT2; GPD2; PCYT2; AGPAT9; CDIPT; GPD1B; PCYT1BA; DGKQ
Ether lipid metabolism
GAL3ST1; PAFAH1B1; PLA2G16; PLA2G12A; PLA2G7; PLA2G4C; TMEM86B; PAFAH1B1A; LPCAT1; PPAP2D
Arachidonic acid metabolism
GGT5; CYP4A12A; PTGES3A; PLA2G2A; FAAH2; AKR1C6; GPX8; PLA2G4C; CYP2C9; CYP2C8
Linoleic acid metabolism
PLA2G5; CYP2C19; PLA2G2F; PLA2G4F; CYP2C45; DHRS13L1; CYP2P7; PLA2G2E; CYP2C8; PLA2G2D
alpha-Linolenic acid metabolism
PLA2G2E; PLA2G12A; PLA2G4A; FADS2; PLA2G6; ACOX3; PLA2G4AA; PLA2G3; ACAA1; PLA2G5
Metabolic pathways
PDXP; PLD3; HAL; GKUP; LASS4; A4GALT; NSDHL; ALG5; GATM; PYGL
MAPK signaling pathway
SRF; FGF20B; MAPK12B; STMN1; CACNG7; FGF7; TGFBR1B; FGF8A; ARRB2B; CASP3A
Ras signaling pathway
LOC608458; PIK3CB; RRAS; FGF18; SOS1; PIK3CG; FGF16; BCL2L1; FLT1; CALM1
Phospholipase D signaling pathway
AKT2; RALGDS; Pdgfa&Pdgfb; SHC3; PLD2; PIK3R1; CYTH3; GRM6; LPAR5; PLA2G4F
Vascular smooth muscle contraction
ADRA1BB; MYL6B; MYLK4; ADCY1B; PPP1R14AA; GNA11; MYH11; PRKCG; PRKCBB; RAF1
VEGF signaling pathway
PLCG2; VEGFA; CDC42L2; PPP3CC; PTK2AB; PIK3R3A; HRASA; PIK3R3B; PIK3R5; RAF1A
Platelet activation
MAPK12; FGG; PIK3CG; PRKG1; ITPR3; LYN; PLCB3; MAPK11; TBXA2R; ACTG1
Fc epsilon RI signaling pathway
PIK3CB; MAP2K3; FCER1A; PIK3CA; RAC1; GRB2; IL3; IL4; MAPK10; BTK
Glutamatergic synapse
GRIK1; SLC1A7; PRKACB; GRM5; PLD1; GNAQ; GNG10; GRIA4; GNAO1; GNG7
Serotonergic synapse
GNAS; HTR6; HTR4; NRAS; GNG10; HTR2A; APP; PRKCB; MAOA; CYP2C37
Long-term depression
GRM1; PLCB1; CRH; PPP2R1B; NOS1; PPP2CB; PLA2G4D; RAF1; GRID2; MAPK1
Inflammatory mediator regulation of TRP channels
CYP2J5; ASIC5; PLCB2; BDKRB1; PTGER2; PRKACB; CAMK2D; PPP1CB; PRKCG; HTR2C
GnRH signaling pathway
CAMK2D1; GNRHR1; CAMK2D; PRKCDA; CACNA1DA; CAMK2B1; GNRH3; MAP2K4B; MAPK14A; MAPK8A
Ovarian steroidogenesis
FSHR; STAR; HSD17B1; FSHB; PLA2G4F; LHB; GNAS; INSR; CYP2J6; HSD3B4
Oxytocin signaling pathway
MYLK4; PLCB2; CAMKK1; PRKACA; ROCK2; GNAS; PPP1CB; CACNG7; PLA2G4A; ROCK1
Choline metabolism in cancer
NRAS; RAC1; RPS6KB2; PLD1; RAC2; PLA2G4A; PLA2G4D; WASF1; PIP5K1A; PLA2G4B

Protein Function

PLA2G4C has several biochemical functions, for example, calcium-independent phospholipase A2 activity, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4C itself. We selected most functions PLA2G4C had, and list some proteins which have the same functions with PLA2G4C. You can find most of the proteins on our site.
Function
Related Protein
Function calcium-independent phospholipase A2 activity
Related Protein PLA2G7; PLA2G4C; PNPLA8; PLA2G15
Function phospholipid binding
Related Protein NR5A2; GRK5; FABP1; PRKCI; NR5A1; MTAP1B; ANXA1; PAFAH2; SHC1; PICALMB