pla2g4c
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  • Official Full Name
  • phospholipase A2, group IVC (cytosolic, calcium-independent)
  • Background
  • Cytosolic phospholipase A2 (cPLA2) is a ubiquitously distributed enzyme that catalyzes the hydrolysis of the sn-2 acyl bond of glycerolipids to produce lysophospholipids and release arachidonic acid. cPLA2 has been implicated in diverse cellular responses
  • Synonyms
  • PLA2G4C; phospholipase A2, group IVC (cytosolic, calcium-independent); cytosolic phospholipase A2 gamma; cPLA2 gamma; phospholipase A2 group IVC; CPLA2-gamma; FLJ42247; FLJ44164; DKFZp586C0423
Cat.#:PLA2G4C-1753HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLA2G4C, His-tagged
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Cat.#:PLA2G4C-3140HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PLA2G4C 293 Cell Lysate
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Involved Pathway

PLA2G4C involved in several pathways and played different roles in them. We selected most pathways PLA2G4C participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4C were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycerophospholipid metabolism
PNPLA7; DGKQ; PLA2G4D; LPCAT3; LPCAT1; EPT1; ETNK1; GPD1; GPD2; PCYT1AB
Ether lipid metabolism
PLA2G4F; PAFAH1B1A; CEPT1; PAFAH1B2; PLA2G4D; PLA2G4C; LPCAT1; PLA2G2F; PLA2G4A; TMEM86B
Arachidonic acid metabolism
CYP2C9; TBXAS1; CYP4F14; CYP2V1; GPX6; CYP2C8; PLA2G4D; CYP2C70; PTGES; CYP2C38
Linoleic acid metabolism
CYP2J5; PLA2G1B; PLA2G2F; ALOX15; PLA2G12A; CYP2J6; CYP3A41A; CYP2P6; CYP2C19; CYP2P10
alpha-Linolenic acid metabolism
PLA2G4AA; PLA2G2A; PLA2G2F; FADS2; PLA2G12A; PLA2G4D; PLA2G4F; PLA2G6; ACOX3; PLA2G2D
Metabolic pathways
CYP19A1A; UGT1AB; PLCD1B; GFPT1; FUT9A; NDUFV2; UGT5G1; DHFRL1; NDUFB6; ITPKA
MAPK signaling pathway
GRB2; HSPA2; FGF7; RAC1A; MAP3K12; ARR3A; DDIT3; MEF2CB; TRAF2; PAK2B
Ras signaling pathway
HGF; RGL1; TEK; RRAS2; PDGFRA; PLA2G2E; GNG2; PRKCB; PLA2G3; PLA1A
Phospholipase D signaling pathway
RALB; RALGDS; PDGFB; PTGFR; PDGFD; GRM2; MTOR; INS2; FCER1A; HRAS
Vascular smooth muscle contraction
ACTA2; PLCB4; PLA2G5; CACNA1SB; MAP2K2; CACNA1SA; MAPK3; PLA2G10; ARHGEF12; MYH11
VEGF signaling pathway
CDC42L; CDC42; PTGS2; AKT2L; HRAS; PIK3CA; PLA2G4D; PPP3CA; PLA2G4C; PRKCBA
Platelet activation
PLA2G4C; FGG; PRKCZ; AKT2; PLA2G4D; PPP1CC; PIK3R3; PRKACA; STIM1; MAPK1
Fc epsilon RI signaling pathway
PIK3CB; SYK; MAPK8; PLA2G4C; PLCG1; MAP2K4; PIK3R3; IL4; GM-CSF; MAP2K6
Glutamatergic synapse
PLA2G4F; MAPK3; GNAO1; GRIA2; SHANK3; PPP3R1; PPP3CB; SHANK1; GNB3; PRKCG
Serotonergic synapse
GNG11; GNAI3; GNG5; GNG7; ALOX15; PLA2G4D; CYP2C54; NRAS; ALOX5; ARAF
Long-term depression
NRAS; GNA12; NOS1; PRKG1; PPP2R1A; PLCB1; CRHR1; GNAQ; GNAZ; PLA2G4D
Inflammatory mediator regulation of TRP channels
CYP2C55; PLCB3; PRKCE; PLCB4; IL1B; TRPV3; MAPK8; TRPV1; IGF1; PLCB2
GnRH signaling pathway
CAMK2D; PRKACAA; MAP2K6; LHB; HRASB; GNRHR4; CALM; ATF4; MAPK9; GNRHR2
Ovarian steroidogenesis
HSD17B1; CYP2J5; FSHB; STAR; LDLR; HSD3B4; BMP15; BMP6; AKR1C3; INS
Oxytocin signaling pathway
MEF2C; ROCK1; MYLK; CALM2; PRKACB; CAMK2B; MYLK3; KRAS; PRKCA; NFATC2
Choline metabolism in cancer
GRB2; PDGFB; PCYT1A; GPCPD1; MTOR; PIK3CD; RAF1; DGKE; WAS; WASF2

Protein Function

PLA2G4C has several biochemical functions, for example, calcium-independent phospholipase A2 activity, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4C itself. We selected most functions PLA2G4C had, and list some proteins which have the same functions with PLA2G4C. You can find most of the proteins on our site.
Function
Related Protein
Function calcium-independent phospholipase A2 activity
Related Protein PLA2G4C; PLA2G15; PNPLA8; PLA2G7
Function phospholipid binding
Related Protein F3; MYOF; PLA2G4C; SMURF1; PICALMA; CPS1; SDPR; GOT2; TEC; BPIFC