| Official Full Name | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| Background | Cytosolic phospholipase A2 (cPLA2) is a ubiquitously distributed enzyme that catalyzes the hydrolysis of the sn-2 acyl bond of glycerolipids to produce lysophospholipids and release arachidonic acid. cPLA2 has been implicated in diverse cellular responses |
| Synonyms | PLA2G4C; phospholipase A2, group IVC (cytosolic, calcium-independent); cytosolic phospholipase A2 gamma; cPLA2 gamma; phospholipase A2 group IVC; CPLA2-gamma; FLJ42247; FLJ44164; DKFZp586C0423 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
PLA2G4C involved in several pathways and played different roles in them. We selected most pathways PLA2G4C participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerophospholipid metabolism | AGPAT5; LPCAT3; PLA2G12A; GPAT2; PCYT1AA; LPIN3; PCYT1BB; GPD2; PCYT1AB; PNPLA6 |
| Ether lipid metabolism | PLB1; PLA2G2E; PLA2G12A; GAL3ST1; PAFAH1B2; PPAP2C; LPCAT1; CHPT1; PLD4; PPAP2CB |
| Arachidonic acid metabolism | GPX2; PLA2G2D; CYP4F18; CYP1A2; ALOX5; CYP4A12A; PLA2G4A; TBXAS1; PTGESL; PTGS2A |
| Linoleic acid metabolism | CYP2J5; CYP3A65; ALOX15; CYP2C9; PLA2G4D; CYP2C37; CYP2C8; CYP2C70; PLA2G4AA; CYP2C50 |
| alpha-Linolenic acid metabolism | PLA2G2E; PLA2G2D; ACOX1; PLA2G4C; PLA2G2F; PLA2G5; PLA2G6; PLA2G12A; PLA2G4F; PLA2G1B |
| Metabolic pathways | Ckmm; PIGV; PFKMB; POLR3GLB; CYP3A5; ATP5IB; POC1B-GALNT4; ATP5C1; C1GALT1B; LPCAT2 |
| MAPK signaling pathway | FLNC; TAOK2; PPP3CB; CACNG4; RAP1A; HRASB; FOS; SRFA; MAP4K1; FGF18A |
| Ras signaling pathway | EFNA4; CALM1; FGF10; GNG8; PLA2G4D; CALM2; PAK1; PLA2G2F; RASAL1; NFKB1 |
| Phospholipase D signaling pathway | MAP2K2; PDGFD; INSR; PPAP2B; AGPAT4; SPHK1; FCER1G; SHC4; GRM5; GRB2 |
| Vascular smooth muscle contraction | CALM4; CALD1; PLA2G2E; MYL6; PLA2G5; PPP1R14AA; CALM1; PRKACBB; GNAS; MLCK2 |
| VEGF signaling pathway | PPP3CA; PIK3R3B; RAC1A; PRKCBA; HSPB1; BADB; PIK3CB; MAPK13; PTGS2B; PPP3CC |
| Platelet activation | ITGA2; PIK3CB; VAMP8; VWF; MAPK13; MAPK1; LYN; PTGS1; RAP1A; PLA2G4D |
| Fc epsilon RI signaling pathway | MS4A2; PIK3CD; PLA2G4F; GAB2; MAP2K3; PIK3CA; FCER1G; PLCG1; AKT1; PDPK1 |
| Glutamatergic synapse | GRM3; TRPC1; DLGAP1; GRM7; SLC1A3; HOMER2; GRIK4; PPP3CA; GNB2; GRIN2A |
| Serotonergic synapse | SLC18A1; HTR1F; SLC6A4; CYP2J5; CYP2C54; HTR4; CYP2J6; HRAS; GNG7; PLCB3 |
| Long-term depression | GUCY1A3; MAPK1; CRH; IGF1; PLA2G4A; NRAS; PRKCA; CRHR1; GNA13; PLCB2 |
| Inflammatory mediator regulation of TRP channels | PTGER2; PLCB2; TRPA1; KLK1B4; PIK3R1; PLCB4; PLCG1; CYP2C55; Adcy4; PRKCG |
| GnRH signaling pathway | PRKCBB; LHB; GNRHR; MAPK9; PLA2G4D; GNRHR2; SOS1; LHBETA1; MAP3K4; CACNA1D |
| Ovarian steroidogenesis | PRKACA; PRKACG; INS2; HSD17B7; FSHB; PLA2G4D; HSD17B2; INS; INS1; IGF1R |
| Oxytocin signaling pathway | PRKAA2; PIK3CB; CACNA2D1; PRKACG; PRKAB2; KCNJ14; CACNG6; Adcy4; ROCK1; CACNA2D4 |
| Choline metabolism in cancer | HRAS; SOS1; PDGFRB; MAPK3; GPCPD1; WASF1; CHKB; PDGFC; PIK3CG; SLC22A1 |
PLA2G4C has several biochemical functions, for example, calcium-independent phospholipase A2 activity, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4C itself. We selected most functions PLA2G4C had, and list some proteins which have the same functions with PLA2G4C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium-independent phospholipase A2 activity | PNPLA8; PLA2G15; PLA2G7; PLA2G4C |
| phospholipid binding | NBEA; SPTBN1; PLA2G7; LRBA; BPIFC; STAP1; GOT2; HIP1RB; Defa4; NOXO1 |
PLA2G4C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G4C here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G4C.
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